Ferrocene-modified amino acids: synthesis and in vivo bioeffects on hippocampus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-01

AUTHORS

А. N. Rodionov, L. V. Snegur, А. А. Simenel, Yu. V. Dobryakova, V. А. Markevich

ABSTRACT

A method for the ferrocene modification of amino acids of natural and synthetic origin has been developed. In the in vivo studies, the hippocampal electrical activity under the action of ferrocenyl(phenylpyrazolyl)glycine (1) was assessed. A meaningful rise (up to 25% compared to the control) in the response amplitudes of the focal potentials of the hippocampal region СА1 after intraperitoneal administration of compound 1 at the dose of 2.0 mg kg–1 was established More... »

PAGES

136-142

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11172-017-1711-1

DOI

http://dx.doi.org/10.1007/s11172-017-1711-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090324958


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0305", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Organic Chemistry", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation", 
          "id": "http://www.grid.ac/institutes/grid.431939.5", 
          "name": [
            "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodionov", 
        "givenName": "\u0410. N.", 
        "id": "sg:person.016212142456.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016212142456.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation", 
          "id": "http://www.grid.ac/institutes/grid.431939.5", 
          "name": [
            "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Snegur", 
        "givenName": "L. V.", 
        "id": "sg:person.015074743157.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015074743157.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation", 
          "id": "http://www.grid.ac/institutes/grid.431939.5", 
          "name": [
            "A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Simenel", 
        "givenName": "\u0410. \u0410.", 
        "id": "sg:person.014345475757.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014345475757.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5\u0410 ul. Butlerova, 117485, Moscow, Russian Federation", 
          "id": "http://www.grid.ac/institutes/grid.418743.d", 
          "name": [
            "Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5\u0410 ul. Butlerova, 117485, Moscow, Russian Federation"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dobryakova", 
        "givenName": "Yu. V.", 
        "id": "sg:person.01105463763.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105463763.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5\u0410 ul. Butlerova, 117485, Moscow, Russian Federation", 
          "id": "http://www.grid.ac/institutes/grid.418743.d", 
          "name": [
            "Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5\u0410 ul. Butlerova, 117485, Moscow, Russian Federation"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Markevich", 
        "givenName": "V. \u0410.", 
        "id": "sg:person.01274622374.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274622374.20"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11172-010-0093-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035706545", 
          "https://doi.org/10.1007/s11172-010-0093-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10904-004-2371-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020107004", 
          "https://doi.org/10.1007/s10904-004-2371-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10904-004-2380-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027368196", 
          "https://doi.org/10.1007/s10904-004-2380-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/bter:86:1:73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024611544", 
          "https://doi.org/10.1385/bter:86:1:73"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11172-014-0756-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005295323", 
          "https://doi.org/10.1007/s11172-014-0756-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00901345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006310632", 
          "https://doi.org/10.1007/bf00901345"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11172-014-0390-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003271293", 
          "https://doi.org/10.1007/s11172-014-0390-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00771574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001437732", 
          "https://doi.org/10.1007/bf00771574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11172-010-0377-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030181574", 
          "https://doi.org/10.1007/s11172-010-0377-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/361031a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042608618", 
          "https://doi.org/10.1038/361031a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11172-013-0298-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052926095", 
          "https://doi.org/10.1007/s11172-013-0298-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11172-014-0736-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043870335", 
          "https://doi.org/10.1007/s11172-014-0736-y"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-01", 
    "datePublishedReg": "2017-01-01", 
    "description": "A method for the ferrocene modification of amino acids of natural and synthetic origin has been developed. In the in vivo studies, the hippocampal electrical activity under the action of ferrocenyl(phenylpyrazolyl)glycine (1) was assessed. A meaningful rise (up to 25% compared to the control) in the response amplitudes of the focal potentials of the hippocampal region \u0421\u04101 after intraperitoneal administration of compound 1 at the dose of 2.0 mg kg\u20131 was established", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11172-017-1711-1", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1022309", 
        "issn": [
          "1066-5285", 
          "1573-9171"
        ], 
        "name": "Russian Chemical Bulletin", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "66"
      }
    ], 
    "keywords": [
      "hippocampal electrical activity", 
      "intraperitoneal administration", 
      "focal potentials", 
      "hippocampal region", 
      "vivo studies", 
      "electrical activity", 
      "meaningful rise", 
      "response amplitude", 
      "amino acids", 
      "hippocampus", 
      "administration", 
      "dose", 
      "acid", 
      "synthetic origin", 
      "activity", 
      "study", 
      "action", 
      "bioeffects", 
      "vivo bioeffects", 
      "compound 1", 
      "ferrocene modification", 
      "potential", 
      "origin", 
      "rise", 
      "amplitude", 
      "modification", 
      "region", 
      "method", 
      "synthesis", 
      "ferrocene"
    ], 
    "name": "Ferrocene-modified amino acids: synthesis and in vivo bioeffects on hippocampus", 
    "pagination": "136-142", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1090324958"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11172-017-1711-1"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11172-017-1711-1", 
      "https://app.dimensions.ai/details/publication/pub.1090324958"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_747.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11172-017-1711-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11172-017-1711-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11172-017-1711-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11172-017-1711-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11172-017-1711-1'


 

This table displays all metadata directly associated to this object as RDF triples.

166 TRIPLES      21 PREDICATES      67 URIs      47 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11172-017-1711-1 schema:about anzsrc-for:03
2 anzsrc-for:0305
3 schema:author N98702537863743628b485e35daa8d453
4 schema:citation sg:pub.10.1007/bf00771574
5 sg:pub.10.1007/bf00901345
6 sg:pub.10.1007/s10904-004-2371-9
7 sg:pub.10.1007/s10904-004-2380-8
8 sg:pub.10.1007/s11172-010-0093-4
9 sg:pub.10.1007/s11172-010-0377-8
10 sg:pub.10.1007/s11172-013-0298-4
11 sg:pub.10.1007/s11172-014-0390-4
12 sg:pub.10.1007/s11172-014-0736-y
13 sg:pub.10.1007/s11172-014-0756-7
14 sg:pub.10.1038/361031a0
15 sg:pub.10.1385/bter:86:1:73
16 schema:datePublished 2017-01
17 schema:datePublishedReg 2017-01-01
18 schema:description A method for the ferrocene modification of amino acids of natural and synthetic origin has been developed. In the in vivo studies, the hippocampal electrical activity under the action of ferrocenyl(phenylpyrazolyl)glycine (1) was assessed. A meaningful rise (up to 25% compared to the control) in the response amplitudes of the focal potentials of the hippocampal region СА1 after intraperitoneal administration of compound 1 at the dose of 2.0 mg kg–1 was established
19 schema:genre article
20 schema:isAccessibleForFree false
21 schema:isPartOf N7507efcb9d7d48a2bffb4e3616ff1e49
22 Nab239f64b174428faf53fb39ec05f658
23 sg:journal.1022309
24 schema:keywords acid
25 action
26 activity
27 administration
28 amino acids
29 amplitude
30 bioeffects
31 compound 1
32 dose
33 electrical activity
34 ferrocene
35 ferrocene modification
36 focal potentials
37 hippocampal electrical activity
38 hippocampal region
39 hippocampus
40 intraperitoneal administration
41 meaningful rise
42 method
43 modification
44 origin
45 potential
46 region
47 response amplitude
48 rise
49 study
50 synthesis
51 synthetic origin
52 vivo bioeffects
53 vivo studies
54 schema:name Ferrocene-modified amino acids: synthesis and in vivo bioeffects on hippocampus
55 schema:pagination 136-142
56 schema:productId N32d3a27dbee347a087be50bba1437802
57 N33b70c5bc0d84c8a96ee477945f48702
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090324958
59 https://doi.org/10.1007/s11172-017-1711-1
60 schema:sdDatePublished 2022-09-02T16:00
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher Naa5237fe2758432891b48512d759967e
63 schema:url https://doi.org/10.1007/s11172-017-1711-1
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N09230a95cb5e44debd71b7b1a9423f72 rdf:first sg:person.01274622374.20
68 rdf:rest rdf:nil
69 N32d3a27dbee347a087be50bba1437802 schema:name dimensions_id
70 schema:value pub.1090324958
71 rdf:type schema:PropertyValue
72 N33b70c5bc0d84c8a96ee477945f48702 schema:name doi
73 schema:value 10.1007/s11172-017-1711-1
74 rdf:type schema:PropertyValue
75 N7507efcb9d7d48a2bffb4e3616ff1e49 schema:volumeNumber 66
76 rdf:type schema:PublicationVolume
77 N98702537863743628b485e35daa8d453 rdf:first sg:person.016212142456.86
78 rdf:rest Nbf26c2c8c7674a44979eb1e86b064582
79 Na6977cacb365484ab6f39bf47b6d01b5 rdf:first sg:person.014345475757.92
80 rdf:rest Ned386f3408f4471e821ee084cadf6fab
81 Naa5237fe2758432891b48512d759967e schema:name Springer Nature - SN SciGraph project
82 rdf:type schema:Organization
83 Nab239f64b174428faf53fb39ec05f658 schema:issueNumber 1
84 rdf:type schema:PublicationIssue
85 Nbf26c2c8c7674a44979eb1e86b064582 rdf:first sg:person.015074743157.37
86 rdf:rest Na6977cacb365484ab6f39bf47b6d01b5
87 Ned386f3408f4471e821ee084cadf6fab rdf:first sg:person.01105463763.55
88 rdf:rest N09230a95cb5e44debd71b7b1a9423f72
89 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
90 schema:name Chemical Sciences
91 rdf:type schema:DefinedTerm
92 anzsrc-for:0305 schema:inDefinedTermSet anzsrc-for:
93 schema:name Organic Chemistry
94 rdf:type schema:DefinedTerm
95 sg:journal.1022309 schema:issn 1066-5285
96 1573-9171
97 schema:name Russian Chemical Bulletin
98 schema:publisher Springer Nature
99 rdf:type schema:Periodical
100 sg:person.01105463763.55 schema:affiliation grid-institutes:grid.418743.d
101 schema:familyName Dobryakova
102 schema:givenName Yu. V.
103 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105463763.55
104 rdf:type schema:Person
105 sg:person.01274622374.20 schema:affiliation grid-institutes:grid.418743.d
106 schema:familyName Markevich
107 schema:givenName V. А.
108 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274622374.20
109 rdf:type schema:Person
110 sg:person.014345475757.92 schema:affiliation grid-institutes:grid.431939.5
111 schema:familyName Simenel
112 schema:givenName А. А.
113 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014345475757.92
114 rdf:type schema:Person
115 sg:person.015074743157.37 schema:affiliation grid-institutes:grid.431939.5
116 schema:familyName Snegur
117 schema:givenName L. V.
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015074743157.37
119 rdf:type schema:Person
120 sg:person.016212142456.86 schema:affiliation grid-institutes:grid.431939.5
121 schema:familyName Rodionov
122 schema:givenName А. N.
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016212142456.86
124 rdf:type schema:Person
125 sg:pub.10.1007/bf00771574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001437732
126 https://doi.org/10.1007/bf00771574
127 rdf:type schema:CreativeWork
128 sg:pub.10.1007/bf00901345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006310632
129 https://doi.org/10.1007/bf00901345
130 rdf:type schema:CreativeWork
131 sg:pub.10.1007/s10904-004-2371-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020107004
132 https://doi.org/10.1007/s10904-004-2371-9
133 rdf:type schema:CreativeWork
134 sg:pub.10.1007/s10904-004-2380-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027368196
135 https://doi.org/10.1007/s10904-004-2380-8
136 rdf:type schema:CreativeWork
137 sg:pub.10.1007/s11172-010-0093-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035706545
138 https://doi.org/10.1007/s11172-010-0093-4
139 rdf:type schema:CreativeWork
140 sg:pub.10.1007/s11172-010-0377-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030181574
141 https://doi.org/10.1007/s11172-010-0377-8
142 rdf:type schema:CreativeWork
143 sg:pub.10.1007/s11172-013-0298-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052926095
144 https://doi.org/10.1007/s11172-013-0298-4
145 rdf:type schema:CreativeWork
146 sg:pub.10.1007/s11172-014-0390-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003271293
147 https://doi.org/10.1007/s11172-014-0390-4
148 rdf:type schema:CreativeWork
149 sg:pub.10.1007/s11172-014-0736-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1043870335
150 https://doi.org/10.1007/s11172-014-0736-y
151 rdf:type schema:CreativeWork
152 sg:pub.10.1007/s11172-014-0756-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005295323
153 https://doi.org/10.1007/s11172-014-0756-7
154 rdf:type schema:CreativeWork
155 sg:pub.10.1038/361031a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042608618
156 https://doi.org/10.1038/361031a0
157 rdf:type schema:CreativeWork
158 sg:pub.10.1385/bter:86:1:73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024611544
159 https://doi.org/10.1385/bter:86:1:73
160 rdf:type schema:CreativeWork
161 grid-institutes:grid.418743.d schema:alternateName Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5А ul. Butlerova, 117485, Moscow, Russian Federation
162 schema:name Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, 5А ul. Butlerova, 117485, Moscow, Russian Federation
163 rdf:type schema:Organization
164 grid-institutes:grid.431939.5 schema:alternateName A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation
165 schema:name A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation
166 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...