Metal polyacrylates, ferrocene derivatives, and polysuccinimide as potential antitumor drugs View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-05

AUTHORS

L. A. Ostrovskaya, S. D. Varfolomeev, M. G. Voronkov, D. B. Korman, N. V. Bluchterova, M. M. Fomina, V. A. Rikova, V. M. Goldberg, K. A. Abzaeva, L. V. Zhilitskaya, L. V. Snegur, A. A. Simenel, S. I. Zykova

ABSTRACT

Compounds belonging to three novel groups of oncological drugs (metal polyacrylates, ferrocene derivatives, and polysuccinimide) showed antitumor activity. The most efficient compounds, viz., gold polyacrylate (auracryl), 2-[(1-ferrocenylethyl)sulfanyl]pyrimidine (LS-17), and polysuccinimide, inhibit the growth of murine solid tumors by 70–95% and are recommended for further thorough preclinical studies of their antitumor properties and mechanisms of action. More... »

PAGES

1211-1217

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11172-014-0575-x

DOI

http://dx.doi.org/10.1007/s11172-014-0575-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005877113


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