Synthesis of β-d-galactopyranosylamine derivatives with the terminal amino group in the spacer as mono-, di-, and trivalent ligands of galectins View Full Text


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Article Info

DATE

2008-11

AUTHORS

L. M. Likhosherstov, O. S. Novikova, G. V. Mokrov

ABSTRACT

Glycoclusters were obtained by N-alkylation of N-glycyl-β-d-galactopyranosylamine with N-chloroacetyl derivatives of β-d-galactopyranosylamine and N,N″-iminodiacetyl-di-β-d-galactopyranosylamine. The glycoclusters with two and three galactopyranosylamine residues and the monovalent ligand N-diglycyl-β-d-galactopyranosylamine with an amino group in the spacer are suitable for subsequent conjugation with carboxyl-containing physiologically active compounds.

PAGES

2418

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11172-008-0345-8

DOI

http://dx.doi.org/10.1007/s11172-008-0345-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029695729


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