Skin manifestations of Cushing’s syndrome View Full Text


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Article Info

DATE

2016-09

AUTHORS

Constantine A. Stratakis

ABSTRACT

Among the most common diagnostic manifestations of Cushing's syndrome (CS) are those involving the skin; they include violaceous striae, facial acne, hirsutism, acanthosis nigricans (AN), fungal infections, hyperpigmentation (Hp) and easy bruisability. Fortunately, most resolve within a year or two after cure of CS, although light-colored striae can persist for years depending on the age of the patients. AN, Hp, and bruisability usually resolve within months after cure in almost all ages. Facial plethora (along with acne and other facial skin changes) is a typical sign of CS that is due to increased perfusion. It resolves immediately after curative therapy of CS. Typically, the severity of the manifestations does not correlate with the biochemical indices of the disease, pointing to age, gender, genetic and skin-type differences that determine the cutaneous manifestations of CS. More... »

PAGES

283-286

References to SciGraph publications

  • 2016-09. Flushing in (neuro)endocrinology in REVIEWS IN ENDOCRINE AND METABOLIC DISORDERS
  • 1996-03. Glucocorticoid receptor localization in human epidermal cells in ARCHIVES OF DERMATOLOGICAL RESEARCH
  • 1995-10. Suppression of Keratinocyte Growth Factor Expression by Glucocorticoids In Vitro and During Wound Healing in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11154-016-9399-3

    DOI

    http://dx.doi.org/10.1007/s11154-016-9399-3

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27943005


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