Quantifying clinical change: discrepancies between patients’ and providers’ perspectives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-09

AUTHORS

Rachel P. Dreyer, Philip G. Jones, Shelby Kutty, John A. Spertus

ABSTRACT

PURPOSE: Interpreting the clinical significance of changes in patient-reported outcomes (PROs) is critically important. The most commonly used approach is to anchor mean changes on PRO scores against a global assessment of change. Whether the assessor of global change should be patients or their physicians is unknown. We compared patients' and physicians' assessments of change over time to examine which was more aligned with patients' changes in PRO measures. METHODS: A total of 459 chronic heart failure patients aged >30 years were enrolled from 13 US centers. Data were obtained by medical record abstraction, physical assessments, and patient interviews at a baseline clinic visit and 6 weeks later. Health status was measured with the disease-specific Kansas City Cardiomyopathy Questionnaire (KCCQ), and both patients and physicians completed a validated 15-level global assessment of change, ranging from large deterioration to large improvement. RESULTS: There was substantial variation between physicians/patients' global assessment of clinical change (weighted kappa = 0.36, 95 % CI 0.28, 0.43). Overall, physician assessments were more strongly correlated with change on the KCCQ summary score than were patients' assessments (physician R = 0.37, patient R = 0.29). CONCLUSION: There was substantial variation between patients' and physicians' global assessment of 6-week change in heart failure status. Physician assessments of the importance of clinical changes were more strongly associated with changes in all domains of patient-reported health status, as assessed by the KCCQ, and may provide a more consistent method for defining the clinical importance of changes in patients' health status. More... »

PAGES

2213-2220

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11136-016-1267-9

DOI

http://dx.doi.org/10.1007/s11136-016-1267-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043341982

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26995561


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