Self-reported health-related quality of life predicts survival for patients with advanced gastric cancer treated with first-line chemotherapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-03

AUTHORS

Se Hoon Park, Moon Sook Cho, Young Saing Kim, Junshik Hong, Eunmi Nam, Jinny Park, Eun Kyung Cho, Dong Bok Shin, Jae Hoon Lee, Woon Kee Lee

ABSTRACT

PURPOSE: To determine whether patients' self-reported quality-of-life (QOL) parameters could predict survival for patients with advanced gastric cancer (AGC) treated with first-line chemotherapy, we performed this analysis based on the data obtained from 254 patients enrolled in three consecutive prospective randomized trials at a single institution. METHODS: Consenting patients with AGC received first-line chemotherapy as specified in the protocols. QOL was assessed at baseline using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaires. Baseline univariate and multivariate analyses were performed on the QOL data and the recognized clinical predictors for survival. RESULTS: Of 254 patients, 164 completed the QOL questionnaire at baseline. All patients received fluorouracil-containing first-line chemotherapy for AGC. With 88% observed deaths and a reported median survival of 9.5 months [95% confidence interval (CI) 8.8-10.2 months], there were no significant differences in survival between patients with or without QOL data. The final Cox multivariate model revealed four prognostic factors: age [hazard ratio (HR) 2.08, 95% CI 1.32-3.33, P = 0.002], bone metastasis (HR 2.70, 95% CI 1.30-5.56, P = 0.008), hemoglobin (HR 0.58, 95% CI 0.37-0.92, P = 0.020), and social functioning (HR 0.40, 95% CI 0.23-0.64, P = 0.001). When adjusting for clinical parameters, social functioning was an independently significant prognostic factor for longer survival. CONCLUSION: Baseline social functioning, along with age, presence of bone metastasis, and baseline hemoglobin level, independently predicts survival of AGC patients treated with first-line chemotherapy. QOL assessment should be routinely included to provide useful prognostic information concerning AGC patients. More... »

PAGES

207-214

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11136-008-9307-8

DOI

http://dx.doi.org/10.1007/s11136-008-9307-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007645248

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18224458


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Age Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Combined Chemotherapy Protocols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hemoglobins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Predictive Value of Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proportional Hazards Models", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Randomized Controlled Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Self Concept", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Social Support", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stomach Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Analysis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Se Hoon", 
        "id": "sg:person.012654263241.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012654263241.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cho", 
        "givenName": "Moon Sook", 
        "id": "sg:person.01260255220.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260255220.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Young Saing", 
        "id": "sg:person.01106642133.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106642133.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hong", 
        "givenName": "Junshik", 
        "id": "sg:person.0650207572.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650207572.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nam", 
        "givenName": "Eunmi", 
        "id": "sg:person.0741076517.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741076517.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Jinny", 
        "id": "sg:person.01046204050.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046204050.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cho", 
        "givenName": "Eun Kyung", 
        "id": "sg:person.0712435216.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712435216.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shin", 
        "givenName": "Dong Bok", 
        "id": "sg:person.010163403132.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010163403132.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Jae Hoon", 
        "id": "sg:person.011413516720.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011413516720.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Department of General Surgery, Gachon University Gil Medical Center, 405-760, Incheon, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Woon Kee", 
        "id": "sg:person.01147667720.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147667720.26"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1023/a:1026442201191", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001531261", 
          "https://doi.org/10.1023/a:1026442201191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(00)00144-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003694839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-005-0027-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005170759", 
          "https://doi.org/10.1007/s00280-005-0027-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-005-0027-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005170759", 
          "https://doi.org/10.1007/s00280-005-0027-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200602000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007298427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200602000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007298427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200602000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007298427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200602000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007298427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.02.527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019698641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdm502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020399494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdl501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024102838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-007-0561-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025593323", 
          "https://doi.org/10.1007/s00280-007-0561-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-007-0561-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025593323", 
          "https://doi.org/10.1007/s00280-007-0561-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(97)00049-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026168412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.49.2.227", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026260259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1995.114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030614602", 
          "https://doi.org/10.1038/bjc.1995.114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1995.114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030614602", 
          "https://doi.org/10.1038/bjc.1995.114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lungcan.2003.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034746885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6690085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040193852", 
          "https://doi.org/10.1038/sj.bjc.6690085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6690085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040193852", 
          "https://doi.org/10.1038/sj.bjc.6690085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.9-suppl_2-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044476568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.08.154", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044799628"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:qure.0000021692.81214.70", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049431077", 
          "https://doi.org/10.1023/b:qure.0000021692.81214.70"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1023/a:1008243606668", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056302730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/85.5.365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059818446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4143/crt.2002.34.2.77", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072255393"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074484285", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.3-3-171", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074484285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1992.10.12.1833", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076577641"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-03", 
    "datePublishedReg": "2008-03-01", 
    "description": "PURPOSE: To determine whether patients' self-reported quality-of-life (QOL) parameters could predict survival for patients with advanced gastric cancer (AGC) treated with first-line chemotherapy, we performed this analysis based on the data obtained from 254 patients enrolled in three consecutive prospective randomized trials at a single institution.\nMETHODS: Consenting patients with AGC received first-line chemotherapy as specified in the protocols. QOL was assessed at baseline using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaires. Baseline univariate and multivariate analyses were performed on the QOL data and the recognized clinical predictors for survival.\nRESULTS: Of 254 patients, 164 completed the QOL questionnaire at baseline. All patients received fluorouracil-containing first-line chemotherapy for AGC. With 88% observed deaths and a reported median survival of 9.5 months [95% confidence interval (CI) 8.8-10.2 months], there were no significant differences in survival between patients with or without QOL data. The final Cox multivariate model revealed four prognostic factors: age [hazard ratio (HR) 2.08, 95% CI 1.32-3.33, P = 0.002], bone metastasis (HR 2.70, 95% CI 1.30-5.56, P = 0.008), hemoglobin (HR 0.58, 95% CI 0.37-0.92, P = 0.020), and social functioning (HR 0.40, 95% CI 0.23-0.64, P = 0.001). When adjusting for clinical parameters, social functioning was an independently significant prognostic factor for longer survival.\nCONCLUSION: Baseline social functioning, along with age, presence of bone metastasis, and baseline hemoglobin level, independently predicts survival of AGC patients treated with first-line chemotherapy. QOL assessment should be routinely included to provide useful prognostic information concerning AGC patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11136-008-9307-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1102620", 
        "issn": [
          "0962-9343", 
          "1573-2649"
        ], 
        "name": "Quality of Life Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "17"
      }
    ], 
    "name": "Self-reported health-related quality of life predicts survival for patients with advanced gastric cancer treated with first-line chemotherapy", 
    "pagination": "207-214", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "246a9c77888c70cab4c410fbde879fc75cf7d46bd2687b982eef97f21a130c18"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18224458"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9210257"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11136-008-9307-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1007645248"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11136-008-9307-8", 
      "https://app.dimensions.ai/details/publication/pub.1007645248"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:44", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000520.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11136-008-9307-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11136-008-9307-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11136-008-9307-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11136-008-9307-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11136-008-9307-8'


 

This table displays all metadata directly associated to this object as RDF triples.

284 TRIPLES      21 PREDICATES      71 URIs      41 LITERALS      29 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11136-008-9307-8 schema:about N0e86b92eda6e405c95dd08125beeda50
2 N13f19f24b18442cca36031b539abde52
3 N2ed0f267f1d543db8429cbba67a4427d
4 N3d006d8a1bbf46d4beda9595995e509b
5 N497a4e1844744d7cae99f73e0d5dca05
6 N5aaeb453ce3b44348437356cb6f4b118
7 N5d2fdc10a9ca49a1a0e035e708686c9d
8 N629206e49f584e98921b70b8aa764acd
9 N6901a5c3ada94014a7cc81532fb6c3f5
10 N70feeddbda42442daf3503ff9580a62e
11 N74ce3a29fccf4ef684755c3207b33f7b
12 N7dfab8e78b294b4b9ef7dabfefcddfdc
13 N8487edd9081e45dc89f506d536284374
14 N8781a83c8caa461bb92d2d6597dd5d8b
15 N930ae525b23549f0960b2e8e4f2a2f39
16 Na303e71b5b3e428f8fa3bb868bacfeb4
17 Na533d8e3e0704b9f95ff28ebe7d35cfc
18 Na8983f7235ed4a518ae0bca52365e945
19 Nb39944c695314ea28d750dd9e70f24f6
20 Nd937fbc592934a62a515fb2346f2b499
21 anzsrc-for:11
22 anzsrc-for:1112
23 schema:author Nad20856b29614dd7b3c98384c3659b06
24 schema:citation sg:pub.10.1007/s00280-005-0027-2
25 sg:pub.10.1007/s00280-007-0561-1
26 sg:pub.10.1023/a:1026442201191
27 sg:pub.10.1023/b:qure.0000021692.81214.70
28 sg:pub.10.1038/bjc.1995.114
29 sg:pub.10.1038/sj.bjc.6690085
30 https://app.dimensions.ai/details/publication/pub.1074484285
31 https://doi.org/10.1016/j.lungcan.2003.09.001
32 https://doi.org/10.1016/s0959-8049(00)00144-1
33 https://doi.org/10.1016/s0959-8049(97)00049-x
34 https://doi.org/10.1023/a:1008243606668
35 https://doi.org/10.1093/annonc/mdl501
36 https://doi.org/10.1093/annonc/mdm502
37 https://doi.org/10.1093/jnci/85.5.365
38 https://doi.org/10.1097/00001813-200602000-00015
39 https://doi.org/10.1136/gut.49.2.227
40 https://doi.org/10.1200/jco.1992.10.12.1833
41 https://doi.org/10.1200/jco.2004.08.154
42 https://doi.org/10.1200/jco.2005.02.527
43 https://doi.org/10.1634/theoncologist.3-3-171
44 https://doi.org/10.1634/theoncologist.9-suppl_2-9
45 https://doi.org/10.4143/crt.2002.34.2.77
46 schema:datePublished 2008-03
47 schema:datePublishedReg 2008-03-01
48 schema:description PURPOSE: To determine whether patients' self-reported quality-of-life (QOL) parameters could predict survival for patients with advanced gastric cancer (AGC) treated with first-line chemotherapy, we performed this analysis based on the data obtained from 254 patients enrolled in three consecutive prospective randomized trials at a single institution. METHODS: Consenting patients with AGC received first-line chemotherapy as specified in the protocols. QOL was assessed at baseline using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaires. Baseline univariate and multivariate analyses were performed on the QOL data and the recognized clinical predictors for survival. RESULTS: Of 254 patients, 164 completed the QOL questionnaire at baseline. All patients received fluorouracil-containing first-line chemotherapy for AGC. With 88% observed deaths and a reported median survival of 9.5 months [95% confidence interval (CI) 8.8-10.2 months], there were no significant differences in survival between patients with or without QOL data. The final Cox multivariate model revealed four prognostic factors: age [hazard ratio (HR) 2.08, 95% CI 1.32-3.33, P = 0.002], bone metastasis (HR 2.70, 95% CI 1.30-5.56, P = 0.008), hemoglobin (HR 0.58, 95% CI 0.37-0.92, P = 0.020), and social functioning (HR 0.40, 95% CI 0.23-0.64, P = 0.001). When adjusting for clinical parameters, social functioning was an independently significant prognostic factor for longer survival. CONCLUSION: Baseline social functioning, along with age, presence of bone metastasis, and baseline hemoglobin level, independently predicts survival of AGC patients treated with first-line chemotherapy. QOL assessment should be routinely included to provide useful prognostic information concerning AGC patients.
49 schema:genre research_article
50 schema:inLanguage en
51 schema:isAccessibleForFree false
52 schema:isPartOf N19a8d00beb6e4fd4829ec27004c2f26d
53 N266d9c40f31842eab2fd7533fa89175d
54 sg:journal.1102620
55 schema:name Self-reported health-related quality of life predicts survival for patients with advanced gastric cancer treated with first-line chemotherapy
56 schema:pagination 207-214
57 schema:productId N01e53accd1a24162a03dea6141a9612d
58 N2b47e3256f3b4fd68a182ca9c27b86c6
59 N7abe5d49b83e48688c674329ae679d00
60 N8b0f10b21ba34fef8b8cf1a7b7cbc254
61 N91f2c2cb86c54facaf7b70d866cedb0a
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007645248
63 https://doi.org/10.1007/s11136-008-9307-8
64 schema:sdDatePublished 2019-04-10T16:44
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher Nedc533e5ce0a486e96cfe97e00d46bc0
67 schema:url http://link.springer.com/10.1007%2Fs11136-008-9307-8
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N01e53accd1a24162a03dea6141a9612d schema:name dimensions_id
72 schema:value pub.1007645248
73 rdf:type schema:PropertyValue
74 N0e86b92eda6e405c95dd08125beeda50 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Male
76 rdf:type schema:DefinedTerm
77 N13f19f24b18442cca36031b539abde52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Social Support
79 rdf:type schema:DefinedTerm
80 N19a8d00beb6e4fd4829ec27004c2f26d schema:issueNumber 2
81 rdf:type schema:PublicationIssue
82 N266d9c40f31842eab2fd7533fa89175d schema:volumeNumber 17
83 rdf:type schema:PublicationVolume
84 N2b47e3256f3b4fd68a182ca9c27b86c6 schema:name doi
85 schema:value 10.1007/s11136-008-9307-8
86 rdf:type schema:PropertyValue
87 N2ed0f267f1d543db8429cbba67a4427d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Aged
89 rdf:type schema:DefinedTerm
90 N2ed5e5301ec34815b7fdfcc44d161b27 rdf:first sg:person.01106642133.41
91 rdf:rest N63cd8d1e4e864b5c9d64dcfb3589f9e8
92 N3d006d8a1bbf46d4beda9595995e509b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Survival Analysis
94 rdf:type schema:DefinedTerm
95 N3d56d80889a04628a4a9ff297bed3593 rdf:first sg:person.01046204050.38
96 rdf:rest Nb617a6e0322e43edab4d9bb18a1d5a28
97 N497a4e1844744d7cae99f73e0d5dca05 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Self Concept
99 rdf:type schema:DefinedTerm
100 N577e47f1fb0840278381a5564b879b6d rdf:first sg:person.010163403132.03
101 rdf:rest Nae6265a0a8034532ba12c75e6a9b8e01
102 N5aaeb453ce3b44348437356cb6f4b118 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Humans
104 rdf:type schema:DefinedTerm
105 N5d2fdc10a9ca49a1a0e035e708686c9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Antineoplastic Combined Chemotherapy Protocols
107 rdf:type schema:DefinedTerm
108 N629206e49f584e98921b70b8aa764acd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Middle Aged
110 rdf:type schema:DefinedTerm
111 N63cd8d1e4e864b5c9d64dcfb3589f9e8 rdf:first sg:person.0650207572.80
112 rdf:rest Nde2dddd70c1f419c81d1622930661785
113 N6901a5c3ada94014a7cc81532fb6c3f5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Proportional Hazards Models
115 rdf:type schema:DefinedTerm
116 N6ad9338caa384089b18bc5e63392ac71 rdf:first sg:person.01147667720.26
117 rdf:rest rdf:nil
118 N70feeddbda42442daf3503ff9580a62e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Stomach Neoplasms
120 rdf:type schema:DefinedTerm
121 N74ce3a29fccf4ef684755c3207b33f7b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Quality of Life
123 rdf:type schema:DefinedTerm
124 N78f1fe003db646a0a9b03c24bdc7a407 rdf:first sg:person.01260255220.32
125 rdf:rest N2ed5e5301ec34815b7fdfcc44d161b27
126 N7abe5d49b83e48688c674329ae679d00 schema:name nlm_unique_id
127 schema:value 9210257
128 rdf:type schema:PropertyValue
129 N7dfab8e78b294b4b9ef7dabfefcddfdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Predictive Value of Tests
131 rdf:type schema:DefinedTerm
132 N8487edd9081e45dc89f506d536284374 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Female
134 rdf:type schema:DefinedTerm
135 N8781a83c8caa461bb92d2d6597dd5d8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Hemoglobins
137 rdf:type schema:DefinedTerm
138 N8b0f10b21ba34fef8b8cf1a7b7cbc254 schema:name pubmed_id
139 schema:value 18224458
140 rdf:type schema:PropertyValue
141 N91f2c2cb86c54facaf7b70d866cedb0a schema:name readcube_id
142 schema:value 246a9c77888c70cab4c410fbde879fc75cf7d46bd2687b982eef97f21a130c18
143 rdf:type schema:PropertyValue
144 N930ae525b23549f0960b2e8e4f2a2f39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Randomized Controlled Trials as Topic
146 rdf:type schema:DefinedTerm
147 Na303e71b5b3e428f8fa3bb868bacfeb4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Bone Neoplasms
149 rdf:type schema:DefinedTerm
150 Na533d8e3e0704b9f95ff28ebe7d35cfc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Cohort Studies
152 rdf:type schema:DefinedTerm
153 Na8983f7235ed4a518ae0bca52365e945 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Age Factors
155 rdf:type schema:DefinedTerm
156 Nad20856b29614dd7b3c98384c3659b06 rdf:first sg:person.012654263241.34
157 rdf:rest N78f1fe003db646a0a9b03c24bdc7a407
158 Nae6265a0a8034532ba12c75e6a9b8e01 rdf:first sg:person.011413516720.37
159 rdf:rest N6ad9338caa384089b18bc5e63392ac71
160 Nb39944c695314ea28d750dd9e70f24f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Prognosis
162 rdf:type schema:DefinedTerm
163 Nb617a6e0322e43edab4d9bb18a1d5a28 rdf:first sg:person.0712435216.04
164 rdf:rest N577e47f1fb0840278381a5564b879b6d
165 Nd937fbc592934a62a515fb2346f2b499 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Adult
167 rdf:type schema:DefinedTerm
168 Nde2dddd70c1f419c81d1622930661785 rdf:first sg:person.0741076517.89
169 rdf:rest N3d56d80889a04628a4a9ff297bed3593
170 Nedc533e5ce0a486e96cfe97e00d46bc0 schema:name Springer Nature - SN SciGraph project
171 rdf:type schema:Organization
172 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
173 schema:name Medical and Health Sciences
174 rdf:type schema:DefinedTerm
175 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
176 schema:name Oncology and Carcinogenesis
177 rdf:type schema:DefinedTerm
178 sg:journal.1102620 schema:issn 0962-9343
179 1573-2649
180 schema:name Quality of Life Research
181 rdf:type schema:Periodical
182 sg:person.010163403132.03 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
183 schema:familyName Shin
184 schema:givenName Dong Bok
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010163403132.03
186 rdf:type schema:Person
187 sg:person.01046204050.38 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
188 schema:familyName Park
189 schema:givenName Jinny
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046204050.38
191 rdf:type schema:Person
192 sg:person.01106642133.41 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
193 schema:familyName Kim
194 schema:givenName Young Saing
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106642133.41
196 rdf:type schema:Person
197 sg:person.011413516720.37 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
198 schema:familyName Lee
199 schema:givenName Jae Hoon
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011413516720.37
201 rdf:type schema:Person
202 sg:person.01147667720.26 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
203 schema:familyName Lee
204 schema:givenName Woon Kee
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147667720.26
206 rdf:type schema:Person
207 sg:person.01260255220.32 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
208 schema:familyName Cho
209 schema:givenName Moon Sook
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260255220.32
211 rdf:type schema:Person
212 sg:person.012654263241.34 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
213 schema:familyName Park
214 schema:givenName Se Hoon
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012654263241.34
216 rdf:type schema:Person
217 sg:person.0650207572.80 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
218 schema:familyName Hong
219 schema:givenName Junshik
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650207572.80
221 rdf:type schema:Person
222 sg:person.0712435216.04 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
223 schema:familyName Cho
224 schema:givenName Eun Kyung
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712435216.04
226 rdf:type schema:Person
227 sg:person.0741076517.89 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
228 schema:familyName Nam
229 schema:givenName Eunmi
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741076517.89
231 rdf:type schema:Person
232 sg:pub.10.1007/s00280-005-0027-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005170759
233 https://doi.org/10.1007/s00280-005-0027-2
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/s00280-007-0561-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025593323
236 https://doi.org/10.1007/s00280-007-0561-1
237 rdf:type schema:CreativeWork
238 sg:pub.10.1023/a:1026442201191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001531261
239 https://doi.org/10.1023/a:1026442201191
240 rdf:type schema:CreativeWork
241 sg:pub.10.1023/b:qure.0000021692.81214.70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049431077
242 https://doi.org/10.1023/b:qure.0000021692.81214.70
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/bjc.1995.114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030614602
245 https://doi.org/10.1038/bjc.1995.114
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/sj.bjc.6690085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040193852
248 https://doi.org/10.1038/sj.bjc.6690085
249 rdf:type schema:CreativeWork
250 https://app.dimensions.ai/details/publication/pub.1074484285 schema:CreativeWork
251 https://doi.org/10.1016/j.lungcan.2003.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034746885
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/s0959-8049(00)00144-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003694839
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/s0959-8049(97)00049-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026168412
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1023/a:1008243606668 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056302730
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1093/annonc/mdl501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024102838
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1093/annonc/mdm502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020399494
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1093/jnci/85.5.365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059818446
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1097/00001813-200602000-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007298427
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1136/gut.49.2.227 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026260259
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1200/jco.1992.10.12.1833 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076577641
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1200/jco.2004.08.154 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044799628
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1200/jco.2005.02.527 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019698641
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1634/theoncologist.3-3-171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074484285
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1634/theoncologist.9-suppl_2-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044476568
278 rdf:type schema:CreativeWork
279 https://doi.org/10.4143/crt.2002.34.2.77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072255393
280 rdf:type schema:CreativeWork
281 https://www.grid.ac/institutes/grid.411653.4 schema:alternateName Gachon University Gil Medical Center
282 schema:name Department of General Surgery, Gachon University Gil Medical Center, 405-760, Incheon, Korea
283 Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, 405-760, Incheon, Korea
284 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...