Effect of Diet Supplemented with Quinoa Seeds on Oxidative Status in Plasma and Selected Tissues of High Fructose-Fed Rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-06

AUTHORS

Pawel Pasko, Henryk Barton, Pawel Zagrodzki, Aleksandra Izewska, Miroslaw Krosniak, Malgorzata Gawlik, Maciej Gawlik, Shela Gorinstein

ABSTRACT

Oxidative stress plays an important role as a mediator of damage produced by fructose metabolism. This work was designed to investigate the effect of diet supplemented with quinoa seeds on oxidative stress in plasma, heart, kidney, liver, spleen, lung, testis and pancreas of fructose administered rats. Fructose administration (310 g/kg fodder for 5 weeks) caused oxidative stress that was manifested by the increase in plasma malondialdehyde (MDA) (p<0.05), and by the non-significant changes in the enzymatic antioxidant potential in plasma and most of tissues. Co-administration of quinoa seeds (310 g/kg fodder) maintained normal activities of some enzymes. It also influenced the oxidative stress as was evidenced by decreasing MDA in plasma, and decreasing the activities of antioxidant enzymes (erythrocyte superoxide dismutase - eSOD, catalase -CAT, plasma glutathione peroxidase - pGPX). These findings demonstrate that quinoa seeds can act as a moderate protective agent against potential of fructose-induced changes in rats by reducing lipid peroxidation and by enhancing the antioxidant capacity of blood (plasma) and heart, kidney, testis, lung and pancreas. More... »

PAGES

146-151

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11130-010-0164-6

DOI

http://dx.doi.org/10.1007/s11130-010-0164-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007337061

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20354792


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