Evolution of early eukaryotic cells: genomes, proteomes, and compartments View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-01

AUTHORS

Lawrence Bogorad

ABSTRACT

Eukaryotes arose from an endosymbiotic association of an alpha-proteobacterium-like organism (the ancestor of mitochondria) with a host cell (lacking mitochondria or plastids). Plants arose by the addition of a cyanobacterium-like endosymbiont (the ancestor of plastids) to the two-member association. Each member of the association brought a unique internal environment and a unique genome. Analyses of recently acquired genomic sequences with newly developed algorithms have revealed (a) that the number of endosymbiont genes that remain in eukaryotic cells-principally in the nucleus-is surprisingly large, (b) that protein products of a large number of genes (or their descendents) that entered the association in the genome of the host are now directed to an organelle derived from an endosymbiont, and (c) that protein products of genes traceable to endosymbiont genomes are directed to the nucleo-cytoplasmic compartment. Consideration of these remarkable findings has led to the present suggestion that contemporary eukaryotic cells evolved through continual chance relocation and testing of genes as well as combinations of gene products and biochemical processes in each unique cell compartment derived from a member of the eukaryotic association. Most of these events occurred during about 300 million years, or so, before contemporary forms of eukaryotic cells appear in the fossil record; they continue today. More... »

PAGES

11-21

References to SciGraph publications

  • 2000-12. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana in NATURE
  • 1991-10. Evolution of the Rubisco operon from prokaryotes to algae: Structure and analysis of the rbcS gene of the brown alga Pylaiella littoralis in PLANT MOLECULAR BIOLOGY
  • 1998-03. Molecular biology of gibberellin synthesis in PLANTA
  • 1992-12. Plastid DNA sequence homologies in the tobacco nuclear genome in MOLECULAR GENETICS AND GENOMICS
  • 1998-04. Air synthetase in cowpea nodules: a single gene product targeted to two organelles? in PLANT MOLECULAR BIOLOGY
  • 1998-09. Two birds with one stone: genes that encode products targeted to two or more compartments in PLANT MOLECULAR BIOLOGY
  • 1990-07. Escape of DNA from mitochondria to the nucleus in Saccharomyces cerevisiae in NATURE
  • 2003-05. Mitochondrial gene history and mRNA localization: is there a correlation? in NATURE REVIEWS GENETICS
  • 2003-03. Direct measurement of the transfer rate of chloroplast DNA into the nucleus in NATURE
  • 2001-07. Morphological and ecological complexity in early eukaryotic ecosystems in NATURE
  • 2001-10. An overview of the genome of Nostoc punctiforme, a multicellular, symbiotic cyanobacterium in PHOTOSYNTHESIS RESEARCH
  • 1981-05. Genetic and biochemical implications of the endosymbiotic origin of the chloroplast in JOURNAL OF MOLECULAR EVOLUTION
  • 1990-12. The genetic code in mitochondria and chloroplasts in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 1997-05. An ancestral mitochondrial DNA resembling a eubacterial genome in miniature in NATURE
  • 1984-01. Homologies between nuclear and plastid DNA in spinach in THEORETICAL AND APPLIED GENETICS
  • 1999-07. Identification and characterization of T3/T7 bacteriophage-like RNA polymerase sequences in wheat in PLANT MOLECULAR BIOLOGY
  • 1997-01. The mitochondrial genome of Arabidopsis thaliana contains 57 genes in 366,924 nucleotides in NATURE GENETICS
  • 1983-01. Rearranged mitochondrial genes in the yeast nuclear genome in NATURE
  • 2001-06. The origin and early evolution of mitochondria in GENOME BIOLOGY
  • 1982-10. Mitochondrial and chloroplast genomes of maize have a 12-kilobase DNA sequence in common in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11120-007-9236-3

    DOI

    http://dx.doi.org/10.1007/s11120-007-9236-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000846232

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17912611


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biological Evolution", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Compartmentation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Eukaryotic Cells", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mitochondria", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proteome", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Harvard University", 
              "id": "https://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Department of Molecular and Cellular Biology, The Biological Laboratories, Harvard University, 16 Divinity Ave., 02138, Cambridge, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bogorad", 
            "givenName": "Lawrence", 
            "id": "sg:person.01154236031.60", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154236031.60"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1104/pp.103.032003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000776585"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/embo-reports/kvd086", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000905854"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0378-1119(02)00583-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004163049"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.970902", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004289431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.82.13.4443", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004353114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/301296a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005454057", 
              "https://doi.org/10.1038/301296a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.172390399", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005897801"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/mcp.m300030-mcp200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006352293"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m108575200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006818593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1013840025518", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006974179", 
              "https://doi.org/10.1023/a:1013840025518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0061(20000930)17:3<170::aid-yea25>3.0.co;2-v", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007616658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/dnares/3.3.109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009801344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1005969830314", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010398448", 
              "https://doi.org/10.1023/a:1005969830314"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1522-2683(20001001)21:16<3488::aid-elps3488>3.0.co;2-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010401766"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.pp.44.060193.000305", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010626952"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng0197-57", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011416439", 
              "https://doi.org/10.1038/ng0197-57"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.091110398", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012808822"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.95.12.6854", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014187443"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0167-4889(01)00145-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014978162"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35083562", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015469787", 
              "https://doi.org/10.1038/35083562"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35083562", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015469787", 
              "https://doi.org/10.1038/35083562"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.69.12.3779", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016347421"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1110/ps.8.5.978", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016649968"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1104/pp.120.3.637", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017166797"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.87.12.4576", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018027137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2001-2-6-reviews1018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018462500", 
              "https://doi.org/10.1186/gb-2001-2-6-reviews1018"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01435", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018672005", 
              "https://doi.org/10.1038/nature01435"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0968-0004(00)01684-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019006411"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.13.3.383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019037936"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01936921", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021129020", 
              "https://doi.org/10.1007/bf01936921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01936921", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021129020", 
              "https://doi.org/10.1007/bf01936921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1438-4221(00)80081-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021130382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.082112499", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021476192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/27.8.1767", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021785320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/pcp/pcf041", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022307901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m101140200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023274516"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/pcp/pcf103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023655581"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s004250050274", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024176857", 
              "https://doi.org/10.1007/s004250050274"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0959-437x(99)00020-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024571395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01733906", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026255204", 
              "https://doi.org/10.1007/bf01733906"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01733906", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026255204", 
              "https://doi.org/10.1007/bf01733906"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.240454797", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027097891"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/jmbi.2000.3903", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028412590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1666/0094-8373(2000)026<0386:bpngns>2.0.co;2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031626580"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/346376a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032323056", 
              "https://doi.org/10.1038/346376a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.pp.46.060195.003001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032491556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2787(72)90115-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032678369"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2787(72)90115-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032678369"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1369-5274(99)00013-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032812001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0962-8924(00)89016-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035972670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1063", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037293922", 
              "https://doi.org/10.1038/nrg1063"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1063", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037293922", 
              "https://doi.org/10.1038/nrg1063"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.182432999", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038426679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.5.4.465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038916219"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0167-4889(01)00146-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039201702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1521-1878(199910)21:10<871::aid-bies10>3.0.co;2-q", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039459013"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1006081903354", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039500136", 
              "https://doi.org/10.1023/a:1006081903354"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1432-1033.2003.03359.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039603218"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.004341", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039794832"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1360-1385(00)01574-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040272305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/387493a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041368656", 
              "https://doi.org/10.1038/387493a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.12.3.319", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043948548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2787(72)90217-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044275474"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2787(72)90217-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044275474"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35048692", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044298669", 
              "https://doi.org/10.1038/35048692"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35048692", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044298669", 
              "https://doi.org/10.1038/35048692"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00037066", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044412866", 
              "https://doi.org/10.1007/bf00037066"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00037066", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044412866", 
              "https://doi.org/10.1007/bf00037066"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1430924100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046073389"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/mcp.m100007-mcp200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046354618"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1733211100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046953903"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.2135385100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048715878"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1087361", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048921070"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1360-1385(00)01737-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048989599"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.220399497", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049047277"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.010483", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049622688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00317055", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050626259", 
              "https://doi.org/10.1007/bf00317055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00317055", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050626259", 
              "https://doi.org/10.1007/bf00317055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1006203928189", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051554110", 
              "https://doi.org/10.1023/a:1006203928189"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/299698a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053116149", 
              "https://doi.org/10.1038/299698a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/jmbi.1994.1415", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053744672"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1083523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062448023"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1138359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062455188"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.174.4010.707", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062503827"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2307/3869726", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070467704"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2307/3870939", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070468771"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00279648", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075681108", 
              "https://doi.org/10.1007/bf00279648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1986.tb04464.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077183847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1142/9789812813046_0002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1088778914"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1142/9789812813046_0003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1088778915"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2008-01", 
        "datePublishedReg": "2008-01-01", 
        "description": "Eukaryotes arose from an endosymbiotic association of an alpha-proteobacterium-like organism (the ancestor of mitochondria) with a host cell (lacking mitochondria or plastids). Plants arose by the addition of a cyanobacterium-like endosymbiont (the ancestor of plastids) to the two-member association. Each member of the association brought a unique internal environment and a unique genome. Analyses of recently acquired genomic sequences with newly developed algorithms have revealed (a) that the number of endosymbiont genes that remain in eukaryotic cells-principally in the nucleus-is surprisingly large, (b) that protein products of a large number of genes (or their descendents) that entered the association in the genome of the host are now directed to an organelle derived from an endosymbiont, and (c) that protein products of genes traceable to endosymbiont genomes are directed to the nucleo-cytoplasmic compartment. Consideration of these remarkable findings has led to the present suggestion that contemporary eukaryotic cells evolved through continual chance relocation and testing of genes as well as combinations of gene products and biochemical processes in each unique cell compartment derived from a member of the eukaryotic association. Most of these events occurred during about 300 million years, or so, before contemporary forms of eukaryotic cells appear in the fossil record; they continue today.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s11120-007-9236-3", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1022986", 
            "issn": [
              "0166-8595", 
              "1573-5079"
            ], 
            "name": "Photosynthesis Research", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "95"
          }
        ], 
        "name": "Evolution of early eukaryotic cells: genomes, proteomes, and compartments", 
        "pagination": "11-21", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "0407c9d0036e9c1d60a0b821784b85a1a9656bb360318b1edc227be67301156c"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "17912611"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "100954728"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s11120-007-9236-3"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1000846232"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s11120-007-9236-3", 
          "https://app.dimensions.ai/details/publication/pub.1000846232"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T00:17", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000519.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs11120-007-9236-3"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11120-007-9236-3'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11120-007-9236-3'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11120-007-9236-3'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11120-007-9236-3'


     

    This table displays all metadata directly associated to this object as RDF triples.

    360 TRIPLES      21 PREDICATES      117 URIs      28 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s11120-007-9236-3 schema:about N19934514a227433283be3f2b6e859c38
    2 N29de03984d1046af999a4bb7e62dc0d0
    3 N33a0560a0f8b49aa864ee1f93c8048b3
    4 N50302df719b14a42a0890bc362175990
    5 N7173ad0670ca465d9be71dca42b7c5e0
    6 Nd243e2450ceb42318425b5bb00bc5e18
    7 Nef8bd9a292b8410a9b026b18945f4d21
    8 anzsrc-for:06
    9 anzsrc-for:0604
    10 schema:author N117b3ad667c8424cbdb0059d0d051114
    11 schema:citation sg:pub.10.1007/bf00037066
    12 sg:pub.10.1007/bf00279648
    13 sg:pub.10.1007/bf00317055
    14 sg:pub.10.1007/bf01733906
    15 sg:pub.10.1007/bf01936921
    16 sg:pub.10.1007/s004250050274
    17 sg:pub.10.1023/a:1005969830314
    18 sg:pub.10.1023/a:1006081903354
    19 sg:pub.10.1023/a:1006203928189
    20 sg:pub.10.1023/a:1013840025518
    21 sg:pub.10.1038/299698a0
    22 sg:pub.10.1038/301296a0
    23 sg:pub.10.1038/346376a0
    24 sg:pub.10.1038/35048692
    25 sg:pub.10.1038/35083562
    26 sg:pub.10.1038/387493a0
    27 sg:pub.10.1038/nature01435
    28 sg:pub.10.1038/ng0197-57
    29 sg:pub.10.1038/nrg1063
    30 sg:pub.10.1186/gb-2001-2-6-reviews1018
    31 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<871::aid-bies10>3.0.co;2-q
    32 https://doi.org/10.1002/1097-0061(20000930)17:3<170::aid-yea25>3.0.co;2-v
    33 https://doi.org/10.1002/1522-2683(20001001)21:16<3488::aid-elps3488>3.0.co;2-3
    34 https://doi.org/10.1002/j.1460-2075.1986.tb04464.x
    35 https://doi.org/10.1006/jmbi.1994.1415
    36 https://doi.org/10.1006/jmbi.2000.3903
    37 https://doi.org/10.1016/0005-2787(72)90115-3
    38 https://doi.org/10.1016/0005-2787(72)90217-1
    39 https://doi.org/10.1016/s0167-4889(01)00145-8
    40 https://doi.org/10.1016/s0167-4889(01)00146-x
    41 https://doi.org/10.1016/s0378-1119(02)00583-8
    42 https://doi.org/10.1016/s0959-437x(99)00020-9
    43 https://doi.org/10.1016/s0962-8924(00)89016-9
    44 https://doi.org/10.1016/s0968-0004(00)01684-4
    45 https://doi.org/10.1016/s1360-1385(00)01574-0
    46 https://doi.org/10.1016/s1360-1385(00)01737-4
    47 https://doi.org/10.1016/s1369-5274(99)00013-2
    48 https://doi.org/10.1016/s1438-4221(00)80081-8
    49 https://doi.org/10.1046/j.1432-1033.2003.03359.x
    50 https://doi.org/10.1073/pnas.082112499
    51 https://doi.org/10.1073/pnas.091110398
    52 https://doi.org/10.1073/pnas.1430924100
    53 https://doi.org/10.1073/pnas.172390399
    54 https://doi.org/10.1073/pnas.1733211100
    55 https://doi.org/10.1073/pnas.182432999
    56 https://doi.org/10.1073/pnas.2135385100
    57 https://doi.org/10.1073/pnas.220399497
    58 https://doi.org/10.1073/pnas.240454797
    59 https://doi.org/10.1073/pnas.69.12.3779
    60 https://doi.org/10.1073/pnas.82.13.4443
    61 https://doi.org/10.1073/pnas.87.12.4576
    62 https://doi.org/10.1073/pnas.95.12.6854
    63 https://doi.org/10.1074/jbc.m101140200
    64 https://doi.org/10.1074/jbc.m108575200
    65 https://doi.org/10.1074/mcp.m100007-mcp200
    66 https://doi.org/10.1074/mcp.m300030-mcp200
    67 https://doi.org/10.1083/jcb.13.3.383
    68 https://doi.org/10.1093/dnares/3.3.109
    69 https://doi.org/10.1093/embo-reports/kvd086
    70 https://doi.org/10.1093/nar/27.8.1767
    71 https://doi.org/10.1093/pcp/pcf041
    72 https://doi.org/10.1093/pcp/pcf103
    73 https://doi.org/10.1101/gad.970902
    74 https://doi.org/10.1104/pp.103.032003
    75 https://doi.org/10.1104/pp.120.3.637
    76 https://doi.org/10.1105/tpc.004341
    77 https://doi.org/10.1105/tpc.010483
    78 https://doi.org/10.1105/tpc.12.3.319
    79 https://doi.org/10.1105/tpc.5.4.465
    80 https://doi.org/10.1110/ps.8.5.978
    81 https://doi.org/10.1126/science.1083523
    82 https://doi.org/10.1126/science.1087361
    83 https://doi.org/10.1126/science.1138359
    84 https://doi.org/10.1126/science.174.4010.707
    85 https://doi.org/10.1142/9789812813046_0002
    86 https://doi.org/10.1142/9789812813046_0003
    87 https://doi.org/10.1146/annurev.pp.44.060193.000305
    88 https://doi.org/10.1146/annurev.pp.46.060195.003001
    89 https://doi.org/10.1666/0094-8373(2000)026<0386:bpngns>2.0.co;2
    90 https://doi.org/10.2307/3869726
    91 https://doi.org/10.2307/3870939
    92 schema:datePublished 2008-01
    93 schema:datePublishedReg 2008-01-01
    94 schema:description Eukaryotes arose from an endosymbiotic association of an alpha-proteobacterium-like organism (the ancestor of mitochondria) with a host cell (lacking mitochondria or plastids). Plants arose by the addition of a cyanobacterium-like endosymbiont (the ancestor of plastids) to the two-member association. Each member of the association brought a unique internal environment and a unique genome. Analyses of recently acquired genomic sequences with newly developed algorithms have revealed (a) that the number of endosymbiont genes that remain in eukaryotic cells-principally in the nucleus-is surprisingly large, (b) that protein products of a large number of genes (or their descendents) that entered the association in the genome of the host are now directed to an organelle derived from an endosymbiont, and (c) that protein products of genes traceable to endosymbiont genomes are directed to the nucleo-cytoplasmic compartment. Consideration of these remarkable findings has led to the present suggestion that contemporary eukaryotic cells evolved through continual chance relocation and testing of genes as well as combinations of gene products and biochemical processes in each unique cell compartment derived from a member of the eukaryotic association. Most of these events occurred during about 300 million years, or so, before contemporary forms of eukaryotic cells appear in the fossil record; they continue today.
    95 schema:genre research_article
    96 schema:inLanguage en
    97 schema:isAccessibleForFree false
    98 schema:isPartOf N20e3f515221d4714a26a827fb66f2b59
    99 Nda1e7017d57441838576cb7d678ebc3d
    100 sg:journal.1022986
    101 schema:name Evolution of early eukaryotic cells: genomes, proteomes, and compartments
    102 schema:pagination 11-21
    103 schema:productId N05ff61d91ee1460482501371438372e3
    104 N8e9d216bdece4dd58487ef6715dc4e1c
    105 N92554075a197446bab649e39211ac28a
    106 Nd3595a9b27804732a8c43ac9a60c0570
    107 Nda64ab1eed544770ba2d045efd7d57ca
    108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000846232
    109 https://doi.org/10.1007/s11120-007-9236-3
    110 schema:sdDatePublished 2019-04-11T00:17
    111 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    112 schema:sdPublisher N71d2597a0826448ab857b955e023ea6c
    113 schema:url http://link.springer.com/10.1007%2Fs11120-007-9236-3
    114 sgo:license sg:explorer/license/
    115 sgo:sdDataset articles
    116 rdf:type schema:ScholarlyArticle
    117 N05ff61d91ee1460482501371438372e3 schema:name dimensions_id
    118 schema:value pub.1000846232
    119 rdf:type schema:PropertyValue
    120 N117b3ad667c8424cbdb0059d0d051114 rdf:first sg:person.01154236031.60
    121 rdf:rest rdf:nil
    122 N19934514a227433283be3f2b6e859c38 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Biological Evolution
    124 rdf:type schema:DefinedTerm
    125 N20e3f515221d4714a26a827fb66f2b59 schema:issueNumber 1
    126 rdf:type schema:PublicationIssue
    127 N29de03984d1046af999a4bb7e62dc0d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Genome
    129 rdf:type schema:DefinedTerm
    130 N33a0560a0f8b49aa864ee1f93c8048b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    131 schema:name Mitochondria
    132 rdf:type schema:DefinedTerm
    133 N50302df719b14a42a0890bc362175990 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Eukaryotic Cells
    135 rdf:type schema:DefinedTerm
    136 N7173ad0670ca465d9be71dca42b7c5e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Animals
    138 rdf:type schema:DefinedTerm
    139 N71d2597a0826448ab857b955e023ea6c schema:name Springer Nature - SN SciGraph project
    140 rdf:type schema:Organization
    141 N8e9d216bdece4dd58487ef6715dc4e1c schema:name doi
    142 schema:value 10.1007/s11120-007-9236-3
    143 rdf:type schema:PropertyValue
    144 N92554075a197446bab649e39211ac28a schema:name readcube_id
    145 schema:value 0407c9d0036e9c1d60a0b821784b85a1a9656bb360318b1edc227be67301156c
    146 rdf:type schema:PropertyValue
    147 Nd243e2450ceb42318425b5bb00bc5e18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Proteome
    149 rdf:type schema:DefinedTerm
    150 Nd3595a9b27804732a8c43ac9a60c0570 schema:name pubmed_id
    151 schema:value 17912611
    152 rdf:type schema:PropertyValue
    153 Nda1e7017d57441838576cb7d678ebc3d schema:volumeNumber 95
    154 rdf:type schema:PublicationVolume
    155 Nda64ab1eed544770ba2d045efd7d57ca schema:name nlm_unique_id
    156 schema:value 100954728
    157 rdf:type schema:PropertyValue
    158 Nef8bd9a292b8410a9b026b18945f4d21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    159 schema:name Cell Compartmentation
    160 rdf:type schema:DefinedTerm
    161 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    162 schema:name Biological Sciences
    163 rdf:type schema:DefinedTerm
    164 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    165 schema:name Genetics
    166 rdf:type schema:DefinedTerm
    167 sg:journal.1022986 schema:issn 0166-8595
    168 1573-5079
    169 schema:name Photosynthesis Research
    170 rdf:type schema:Periodical
    171 sg:person.01154236031.60 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
    172 schema:familyName Bogorad
    173 schema:givenName Lawrence
    174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154236031.60
    175 rdf:type schema:Person
    176 sg:pub.10.1007/bf00037066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044412866
    177 https://doi.org/10.1007/bf00037066
    178 rdf:type schema:CreativeWork
    179 sg:pub.10.1007/bf00279648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075681108
    180 https://doi.org/10.1007/bf00279648
    181 rdf:type schema:CreativeWork
    182 sg:pub.10.1007/bf00317055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050626259
    183 https://doi.org/10.1007/bf00317055
    184 rdf:type schema:CreativeWork
    185 sg:pub.10.1007/bf01733906 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026255204
    186 https://doi.org/10.1007/bf01733906
    187 rdf:type schema:CreativeWork
    188 sg:pub.10.1007/bf01936921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021129020
    189 https://doi.org/10.1007/bf01936921
    190 rdf:type schema:CreativeWork
    191 sg:pub.10.1007/s004250050274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024176857
    192 https://doi.org/10.1007/s004250050274
    193 rdf:type schema:CreativeWork
    194 sg:pub.10.1023/a:1005969830314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010398448
    195 https://doi.org/10.1023/a:1005969830314
    196 rdf:type schema:CreativeWork
    197 sg:pub.10.1023/a:1006081903354 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039500136
    198 https://doi.org/10.1023/a:1006081903354
    199 rdf:type schema:CreativeWork
    200 sg:pub.10.1023/a:1006203928189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051554110
    201 https://doi.org/10.1023/a:1006203928189
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1023/a:1013840025518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006974179
    204 https://doi.org/10.1023/a:1013840025518
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1038/299698a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053116149
    207 https://doi.org/10.1038/299698a0
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1038/301296a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005454057
    210 https://doi.org/10.1038/301296a0
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/346376a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032323056
    213 https://doi.org/10.1038/346376a0
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1038/35048692 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044298669
    216 https://doi.org/10.1038/35048692
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1038/35083562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015469787
    219 https://doi.org/10.1038/35083562
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1038/387493a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041368656
    222 https://doi.org/10.1038/387493a0
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1038/nature01435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018672005
    225 https://doi.org/10.1038/nature01435
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1038/ng0197-57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011416439
    228 https://doi.org/10.1038/ng0197-57
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.1038/nrg1063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037293922
    231 https://doi.org/10.1038/nrg1063
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1186/gb-2001-2-6-reviews1018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018462500
    234 https://doi.org/10.1186/gb-2001-2-6-reviews1018
    235 rdf:type schema:CreativeWork
    236 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<871::aid-bies10>3.0.co;2-q schema:sameAs https://app.dimensions.ai/details/publication/pub.1039459013
    237 rdf:type schema:CreativeWork
    238 https://doi.org/10.1002/1097-0061(20000930)17:3<170::aid-yea25>3.0.co;2-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1007616658
    239 rdf:type schema:CreativeWork
    240 https://doi.org/10.1002/1522-2683(20001001)21:16<3488::aid-elps3488>3.0.co;2-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010401766
    241 rdf:type schema:CreativeWork
    242 https://doi.org/10.1002/j.1460-2075.1986.tb04464.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1077183847
    243 rdf:type schema:CreativeWork
    244 https://doi.org/10.1006/jmbi.1994.1415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053744672
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1006/jmbi.2000.3903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028412590
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1016/0005-2787(72)90115-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032678369
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1016/0005-2787(72)90217-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044275474
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1016/s0167-4889(01)00145-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014978162
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1016/s0167-4889(01)00146-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039201702
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1016/s0378-1119(02)00583-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004163049
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1016/s0959-437x(99)00020-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024571395
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.1016/s0962-8924(00)89016-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035972670
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.1016/s0968-0004(00)01684-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019006411
    263 rdf:type schema:CreativeWork
    264 https://doi.org/10.1016/s1360-1385(00)01574-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040272305
    265 rdf:type schema:CreativeWork
    266 https://doi.org/10.1016/s1360-1385(00)01737-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048989599
    267 rdf:type schema:CreativeWork
    268 https://doi.org/10.1016/s1369-5274(99)00013-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032812001
    269 rdf:type schema:CreativeWork
    270 https://doi.org/10.1016/s1438-4221(00)80081-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021130382
    271 rdf:type schema:CreativeWork
    272 https://doi.org/10.1046/j.1432-1033.2003.03359.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039603218
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1073/pnas.082112499 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021476192
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1073/pnas.091110398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012808822
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1073/pnas.1430924100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046073389
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.1073/pnas.172390399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005897801
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.1073/pnas.1733211100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046953903
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.1073/pnas.182432999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038426679
    285 rdf:type schema:CreativeWork
    286 https://doi.org/10.1073/pnas.2135385100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048715878
    287 rdf:type schema:CreativeWork
    288 https://doi.org/10.1073/pnas.220399497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049047277
    289 rdf:type schema:CreativeWork
    290 https://doi.org/10.1073/pnas.240454797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027097891
    291 rdf:type schema:CreativeWork
    292 https://doi.org/10.1073/pnas.69.12.3779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016347421
    293 rdf:type schema:CreativeWork
    294 https://doi.org/10.1073/pnas.82.13.4443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004353114
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.1073/pnas.87.12.4576 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018027137
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1073/pnas.95.12.6854 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014187443
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.1074/jbc.m101140200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023274516
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.1074/jbc.m108575200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006818593
    303 rdf:type schema:CreativeWork
    304 https://doi.org/10.1074/mcp.m100007-mcp200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046354618
    305 rdf:type schema:CreativeWork
    306 https://doi.org/10.1074/mcp.m300030-mcp200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006352293
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1083/jcb.13.3.383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019037936
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1093/dnares/3.3.109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009801344
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1093/embo-reports/kvd086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000905854
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1093/nar/27.8.1767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021785320
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1093/pcp/pcf041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022307901
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1093/pcp/pcf103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023655581
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1101/gad.970902 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004289431
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1104/pp.103.032003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000776585
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1104/pp.120.3.637 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017166797
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1105/tpc.004341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039794832
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.1105/tpc.010483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049622688
    329 rdf:type schema:CreativeWork
    330 https://doi.org/10.1105/tpc.12.3.319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043948548
    331 rdf:type schema:CreativeWork
    332 https://doi.org/10.1105/tpc.5.4.465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038916219
    333 rdf:type schema:CreativeWork
    334 https://doi.org/10.1110/ps.8.5.978 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016649968
    335 rdf:type schema:CreativeWork
    336 https://doi.org/10.1126/science.1083523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062448023
    337 rdf:type schema:CreativeWork
    338 https://doi.org/10.1126/science.1087361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048921070
    339 rdf:type schema:CreativeWork
    340 https://doi.org/10.1126/science.1138359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062455188
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1126/science.174.4010.707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062503827
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1142/9789812813046_0002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1088778914
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1142/9789812813046_0003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1088778915
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1146/annurev.pp.44.060193.000305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010626952
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1146/annurev.pp.46.060195.003001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032491556
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1666/0094-8373(2000)026<0386:bpngns>2.0.co;2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031626580
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.2307/3869726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070467704
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.2307/3870939 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070468771
    357 rdf:type schema:CreativeWork
    358 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
    359 schema:name Department of Molecular and Cellular Biology, The Biological Laboratories, Harvard University, 16 Divinity Ave., 02138, Cambridge, MA, USA
    360 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...