Positive regulation of rice RING E3 ligase OsHIR1 in arsenic and cadmium uptakes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-07

AUTHORS

Sung Don Lim, Jin Gyu Hwang, A. Reum Han, Yong Chan Park, Chanhui Lee, Yong Sik Ok, Cheol Seong Jang

ABSTRACT

The metalloid arsenic (As) and the heavy metal cadmium (Cd) are ubiquitously found at low concentrations in the earth. High concentrations of these elements in the soil and crops are severely dangerous to human health. We attempted to retrieve the RING E3 ubiquitin ligase gene for regulating As and Cd uptakes via the ubiquitin 26S proteasome system. Semi-quantitative reverse transcription polymerase chain reaction was conducted for a total of 47 Oryza sativa RING finger protein (OsRFP) genes to assess their expression patterns when exposed to As and Cd treatments. We identified one gene Oryza sativa heavy metal induced RING E3 ligase 1 (OsHIR1), which was significantly upregulated with both treatments. A yeast hybrid screen and a bimolecular fluorescence complementation assay showed that OsHIR1 clearly interacts with 5 substrate proteins, including tonoplast intrinsic protein 4;1 (OsTIP4;1) in the plasma membrane. In addition, OsHIR1 strongly degraded the protein level of OsTIP4;1 via the ubiquitin 26S proteasome system. Heterogeneous overexpression of OsHIR1 in Arabidopsis exhibited As- and Cd-insensitive phenotypes and resulted in decreased As and Cd accumulation in the shoots and roots, relative to the control. Herein, we report the novel finding that the OsHIR1 E3 ligase positively regulates OsTIP4;1 related to As and Cd uptakes. More... »

PAGES

365-379

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11103-014-0190-0

DOI

http://dx.doi.org/10.1007/s11103-014-0190-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053327510

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24664473


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arsenic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cadmium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Enzymologic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oryza", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Soil", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcriptome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ubiquitin-Protein Ligases", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lim", 
        "givenName": "Sung Don", 
        "id": "sg:person.01060653671.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060653671.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hwang", 
        "givenName": "Jin Gyu", 
        "id": "sg:person.01013074746.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013074746.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Han", 
        "givenName": "A. Reum", 
        "id": "sg:person.01015763360.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015763360.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Yong Chan", 
        "id": "sg:person.0773465727.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773465727.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyung Hee University", 
          "id": "https://www.grid.ac/institutes/grid.289247.2", 
          "name": [
            "Department of Plant Environmental New Resources, KyungHee University, 446-701, Yongin, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Chanhui", 
        "id": "sg:person.01156754607.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156754607.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Department of Biological Environment, Kangwon National University, 200-701, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ok", 
        "givenName": "Yong Sik", 
        "id": "sg:person.01360453633.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360453633.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kangwon National University", 
          "id": "https://www.grid.ac/institutes/grid.412010.6", 
          "name": [
            "Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jang", 
        "givenName": "Cheol Seong", 
        "id": "sg:person.0774561065.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774561065.60"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.semcdb.2012.01.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000712098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2011.04665.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001156143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11103-009-9576-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003207874", 
          "https://doi.org/10.1007/s11103-009-9576-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11103-009-9576-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003207874", 
          "https://doi.org/10.1007/s11103-009-9576-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1469-8137.2003.00655.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003729595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1026298032009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003902907", 
          "https://doi.org/10.1023/a:1026298032009"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/pce.12138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004114631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/dnares/dst011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004428714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/pcp/pci172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005931501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1109127108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006106452"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bc20040133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007245112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bc20040133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007245112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/07853890310016324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008238857"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tplants.2004.07.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009906456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/pcp/pch202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010441240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.107.057380", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012231878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.arplant.59.032607.092734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012295811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1013964107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013509562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.cellbio.19.110701.154617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016222049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1072896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019045153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.arplant.55.031903.141801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019175008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2007.03212.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022119873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8137.2008.02716.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025319328"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pbi.2009.05.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025859026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jxb/ert143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027889262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2009.04109.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033819071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2009.04109.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033819071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.111.180893", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034333020"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11103-011-9775-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035204019", 
          "https://doi.org/10.1007/s11103-011-9775-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.106.041871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036111940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60761-987-1_18", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036490089", 
          "https://doi.org/10.1007/978-1-60761-987-1_18"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60761-987-1_18", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036490089", 
          "https://doi.org/10.1007/978-1-60761-987-1_18"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0802361105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037637133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2006.97", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037952183", 
          "https://doi.org/10.1038/nprot.2006.97"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2006.97", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037952183", 
          "https://doi.org/10.1038/nprot.2006.97"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.104.052423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041630038"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.108.061994", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042113877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047635483", 
          "https://doi.org/10.1038/nrm2688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047635483", 
          "https://doi.org/10.1038/nrm2688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biochi.2006.07.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047669187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jplph.2008.05.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050679502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pbi.2011.07.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051052998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.106.048488", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052662461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkm259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053546100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es070627i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055500521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es070627i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055500521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es802412r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055515533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es802412r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055515533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es802612a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055515603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/es802612a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055515603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1072375", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062446603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/psb.5.6.11425", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072309313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083370018", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-07", 
    "datePublishedReg": "2014-07-01", 
    "description": "The metalloid arsenic (As) and the heavy metal cadmium (Cd) are ubiquitously found at low concentrations in the earth. High concentrations of these elements in the soil and crops are severely dangerous to human health. We attempted to retrieve the RING E3 ubiquitin\u00a0ligase gene for regulating As and Cd uptakes via the ubiquitin 26S proteasome system. Semi-quantitative reverse transcription polymerase chain reaction was conducted for a total of 47 Oryza sativa RING finger protein (OsRFP) genes to assess their expression patterns when exposed to As and Cd treatments. We identified one gene Oryza sativa heavy metal induced RING E3 ligase 1 (OsHIR1), which was significantly upregulated with both treatments. A yeast hybrid screen and a bimolecular fluorescence complementation assay showed that OsHIR1 clearly interacts with 5 substrate proteins, including tonoplast intrinsic protein 4;1 (OsTIP4;1) in the plasma membrane. In addition, OsHIR1 strongly degraded the protein level of OsTIP4;1 via the ubiquitin 26S proteasome system. Heterogeneous overexpression of OsHIR1 in Arabidopsis exhibited As- and Cd-insensitive phenotypes and resulted in decreased As and Cd accumulation in the shoots and roots, relative to the control. Herein, we report the novel finding that the OsHIR1 E3 ligase positively regulates OsTIP4;1 related to As and Cd uptakes. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11103-014-0190-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.7481940", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1101246", 
        "issn": [
          "0167-4412", 
          "1573-5028"
        ], 
        "name": "Plant Molecular Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4-5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "85"
      }
    ], 
    "name": "Positive regulation of rice RING E3 ligase OsHIR1 in arsenic and cadmium uptakes", 
    "pagination": "365-379", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "fe021a764d4ea4f75d84ff6ec9b9555233275904a2e79dd3dc697589e015ece6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24664473"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9106343"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11103-014-0190-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053327510"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11103-014-0190-0", 
      "https://app.dimensions.ai/details/publication/pub.1053327510"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T15:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000524.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11103-014-0190-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11103-014-0190-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11103-014-0190-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11103-014-0190-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11103-014-0190-0'


 

This table displays all metadata directly associated to this object as RDF triples.

298 TRIPLES      21 PREDICATES      84 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11103-014-0190-0 schema:about N0fed7eb262c74540a67ec86192c0cfb9
2 N1ac6981c82ed4127a7be66d033760e97
3 N38e614bdf79f4b37a5b37a09ad2136fb
4 N49c570e2e40b42a2a25e27818503868c
5 N5a863e5f1eae4ec69231f675998294c7
6 N77d803440667492ba17ba12687305aa2
7 N84db094d4fad48c3ad9f1c00455bfc87
8 N8879c67191b54c899b472c34640d3f49
9 N96835a6c9f5844439bb497fcc462b721
10 Naf1c087b28dd4a7ba78362ccbab07a57
11 Nce70436c0c5a432a85a4833815ee6396
12 anzsrc-for:06
13 anzsrc-for:0604
14 schema:author N396dd2aeb4bd40a090d1bfeec62a3963
15 schema:citation sg:pub.10.1007/978-1-60761-987-1_18
16 sg:pub.10.1007/s11103-009-9576-9
17 sg:pub.10.1007/s11103-011-9775-z
18 sg:pub.10.1023/a:1026298032009
19 sg:pub.10.1038/nprot.2006.97
20 sg:pub.10.1038/nrm2688
21 https://app.dimensions.ai/details/publication/pub.1083370018
22 https://doi.org/10.1016/j.biochi.2006.07.003
23 https://doi.org/10.1016/j.jplph.2008.05.002
24 https://doi.org/10.1016/j.pbi.2009.05.001
25 https://doi.org/10.1016/j.pbi.2011.07.004
26 https://doi.org/10.1016/j.semcdb.2012.01.019
27 https://doi.org/10.1016/j.tplants.2004.07.002
28 https://doi.org/10.1021/es070627i
29 https://doi.org/10.1021/es802412r
30 https://doi.org/10.1021/es802612a
31 https://doi.org/10.1042/bc20040133
32 https://doi.org/10.1046/j.1469-8137.2003.00655.x
33 https://doi.org/10.1073/pnas.0802361105
34 https://doi.org/10.1073/pnas.1013964107
35 https://doi.org/10.1073/pnas.1109127108
36 https://doi.org/10.1080/07853890310016324
37 https://doi.org/10.1093/dnares/dst011
38 https://doi.org/10.1093/jxb/ert143
39 https://doi.org/10.1093/nar/gkm259
40 https://doi.org/10.1093/pcp/pch202
41 https://doi.org/10.1093/pcp/pci172
42 https://doi.org/10.1104/pp.104.052423
43 https://doi.org/10.1104/pp.111.180893
44 https://doi.org/10.1105/tpc.106.041871
45 https://doi.org/10.1105/tpc.106.048488
46 https://doi.org/10.1105/tpc.107.057380
47 https://doi.org/10.1105/tpc.108.061994
48 https://doi.org/10.1111/j.1365-313x.2007.03212.x
49 https://doi.org/10.1111/j.1365-313x.2009.04109.x
50 https://doi.org/10.1111/j.1365-313x.2011.04665.x
51 https://doi.org/10.1111/j.1469-8137.2008.02716.x
52 https://doi.org/10.1111/pce.12138
53 https://doi.org/10.1126/science.1072375
54 https://doi.org/10.1126/science.1072896
55 https://doi.org/10.1146/annurev.arplant.55.031903.141801
56 https://doi.org/10.1146/annurev.arplant.59.032607.092734
57 https://doi.org/10.1146/annurev.cellbio.19.110701.154617
58 https://doi.org/10.4161/psb.5.6.11425
59 schema:datePublished 2014-07
60 schema:datePublishedReg 2014-07-01
61 schema:description The metalloid arsenic (As) and the heavy metal cadmium (Cd) are ubiquitously found at low concentrations in the earth. High concentrations of these elements in the soil and crops are severely dangerous to human health. We attempted to retrieve the RING E3 ubiquitin ligase gene for regulating As and Cd uptakes via the ubiquitin 26S proteasome system. Semi-quantitative reverse transcription polymerase chain reaction was conducted for a total of 47 Oryza sativa RING finger protein (OsRFP) genes to assess their expression patterns when exposed to As and Cd treatments. We identified one gene Oryza sativa heavy metal induced RING E3 ligase 1 (OsHIR1), which was significantly upregulated with both treatments. A yeast hybrid screen and a bimolecular fluorescence complementation assay showed that OsHIR1 clearly interacts with 5 substrate proteins, including tonoplast intrinsic protein 4;1 (OsTIP4;1) in the plasma membrane. In addition, OsHIR1 strongly degraded the protein level of OsTIP4;1 via the ubiquitin 26S proteasome system. Heterogeneous overexpression of OsHIR1 in Arabidopsis exhibited As- and Cd-insensitive phenotypes and resulted in decreased As and Cd accumulation in the shoots and roots, relative to the control. Herein, we report the novel finding that the OsHIR1 E3 ligase positively regulates OsTIP4;1 related to As and Cd uptakes.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree false
65 schema:isPartOf N3c9e48cb7c3546a8a3e8642e385bcebd
66 N94ae3a9518134becbc12b8bf68b2a846
67 sg:journal.1101246
68 schema:name Positive regulation of rice RING E3 ligase OsHIR1 in arsenic and cadmium uptakes
69 schema:pagination 365-379
70 schema:productId N1055456d26934d81beff28dcbb25ffea
71 N4260ca8bea3e409daced873e5f798355
72 N69f5557134b045b0bffcf067d9322779
73 Na52a59f1c472405ebf9f63afd9199749
74 Nc4319f84309244388b192a4b51ab99a6
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053327510
76 https://doi.org/10.1007/s11103-014-0190-0
77 schema:sdDatePublished 2019-04-10T15:54
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher N96076b0ed84f45b595c6b4cca1cb49cf
80 schema:url http://link.springer.com/10.1007%2Fs11103-014-0190-0
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N0fed7eb262c74540a67ec86192c0cfb9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Plant Proteins
86 rdf:type schema:DefinedTerm
87 N1055456d26934d81beff28dcbb25ffea schema:name pubmed_id
88 schema:value 24664473
89 rdf:type schema:PropertyValue
90 N1ac6981c82ed4127a7be66d033760e97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Amino Acid Sequence
92 rdf:type schema:DefinedTerm
93 N38e614bdf79f4b37a5b37a09ad2136fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Molecular Sequence Data
95 rdf:type schema:DefinedTerm
96 N396dd2aeb4bd40a090d1bfeec62a3963 rdf:first sg:person.01060653671.47
97 rdf:rest Ne760a7de1d0349578932ec8ca294e4d0
98 N3c9e48cb7c3546a8a3e8642e385bcebd schema:issueNumber 4-5
99 rdf:type schema:PublicationIssue
100 N4260ca8bea3e409daced873e5f798355 schema:name doi
101 schema:value 10.1007/s11103-014-0190-0
102 rdf:type schema:PropertyValue
103 N438546a6c56c47ac83d5120d63855051 rdf:first sg:person.01015763360.22
104 rdf:rest Ndc926ebaaab04c8385bf3b566826c415
105 N49c570e2e40b42a2a25e27818503868c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Arsenic
107 rdf:type schema:DefinedTerm
108 N59d36440a65540039556813e20d9dee9 rdf:first sg:person.0774561065.60
109 rdf:rest rdf:nil
110 N5a863e5f1eae4ec69231f675998294c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Ubiquitin-Protein Ligases
112 rdf:type schema:DefinedTerm
113 N69f5557134b045b0bffcf067d9322779 schema:name nlm_unique_id
114 schema:value 9106343
115 rdf:type schema:PropertyValue
116 N77d803440667492ba17ba12687305aa2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Transcriptome
118 rdf:type schema:DefinedTerm
119 N84db094d4fad48c3ad9f1c00455bfc87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Oryza
121 rdf:type schema:DefinedTerm
122 N8879c67191b54c899b472c34640d3f49 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Cadmium
124 rdf:type schema:DefinedTerm
125 N94ae3a9518134becbc12b8bf68b2a846 schema:volumeNumber 85
126 rdf:type schema:PublicationVolume
127 N96076b0ed84f45b595c6b4cca1cb49cf schema:name Springer Nature - SN SciGraph project
128 rdf:type schema:Organization
129 N96835a6c9f5844439bb497fcc462b721 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Gene Expression Regulation, Enzymologic
131 rdf:type schema:DefinedTerm
132 Na52a59f1c472405ebf9f63afd9199749 schema:name dimensions_id
133 schema:value pub.1053327510
134 rdf:type schema:PropertyValue
135 Naf1c087b28dd4a7ba78362ccbab07a57 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Soil
137 rdf:type schema:DefinedTerm
138 Nc4319f84309244388b192a4b51ab99a6 schema:name readcube_id
139 schema:value fe021a764d4ea4f75d84ff6ec9b9555233275904a2e79dd3dc697589e015ece6
140 rdf:type schema:PropertyValue
141 Nc85c9c6196db4112b229f42eeb693b9b rdf:first sg:person.01360453633.51
142 rdf:rest N59d36440a65540039556813e20d9dee9
143 Nce70436c0c5a432a85a4833815ee6396 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Gene Expression Regulation, Plant
145 rdf:type schema:DefinedTerm
146 Ndc926ebaaab04c8385bf3b566826c415 rdf:first sg:person.0773465727.98
147 rdf:rest Ne492626377f44452a3de4a84ab4674bb
148 Ne492626377f44452a3de4a84ab4674bb rdf:first sg:person.01156754607.44
149 rdf:rest Nc85c9c6196db4112b229f42eeb693b9b
150 Ne760a7de1d0349578932ec8ca294e4d0 rdf:first sg:person.01013074746.45
151 rdf:rest N438546a6c56c47ac83d5120d63855051
152 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
153 schema:name Biological Sciences
154 rdf:type schema:DefinedTerm
155 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
156 schema:name Genetics
157 rdf:type schema:DefinedTerm
158 sg:grant.7481940 http://pending.schema.org/fundedItem sg:pub.10.1007/s11103-014-0190-0
159 rdf:type schema:MonetaryGrant
160 sg:journal.1101246 schema:issn 0167-4412
161 1573-5028
162 schema:name Plant Molecular Biology
163 rdf:type schema:Periodical
164 sg:person.01013074746.45 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
165 schema:familyName Hwang
166 schema:givenName Jin Gyu
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013074746.45
168 rdf:type schema:Person
169 sg:person.01015763360.22 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
170 schema:familyName Han
171 schema:givenName A. Reum
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015763360.22
173 rdf:type schema:Person
174 sg:person.01060653671.47 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
175 schema:familyName Lim
176 schema:givenName Sung Don
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060653671.47
178 rdf:type schema:Person
179 sg:person.01156754607.44 schema:affiliation https://www.grid.ac/institutes/grid.289247.2
180 schema:familyName Lee
181 schema:givenName Chanhui
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156754607.44
183 rdf:type schema:Person
184 sg:person.01360453633.51 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
185 schema:familyName Ok
186 schema:givenName Yong Sik
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360453633.51
188 rdf:type schema:Person
189 sg:person.0773465727.98 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
190 schema:familyName Park
191 schema:givenName Yong Chan
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773465727.98
193 rdf:type schema:Person
194 sg:person.0774561065.60 schema:affiliation https://www.grid.ac/institutes/grid.412010.6
195 schema:familyName Jang
196 schema:givenName Cheol Seong
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774561065.60
198 rdf:type schema:Person
199 sg:pub.10.1007/978-1-60761-987-1_18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036490089
200 https://doi.org/10.1007/978-1-60761-987-1_18
201 rdf:type schema:CreativeWork
202 sg:pub.10.1007/s11103-009-9576-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003207874
203 https://doi.org/10.1007/s11103-009-9576-9
204 rdf:type schema:CreativeWork
205 sg:pub.10.1007/s11103-011-9775-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1035204019
206 https://doi.org/10.1007/s11103-011-9775-z
207 rdf:type schema:CreativeWork
208 sg:pub.10.1023/a:1026298032009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003902907
209 https://doi.org/10.1023/a:1026298032009
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/nprot.2006.97 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037952183
212 https://doi.org/10.1038/nprot.2006.97
213 rdf:type schema:CreativeWork
214 sg:pub.10.1038/nrm2688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047635483
215 https://doi.org/10.1038/nrm2688
216 rdf:type schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1083370018 schema:CreativeWork
218 https://doi.org/10.1016/j.biochi.2006.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047669187
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/j.jplph.2008.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050679502
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/j.pbi.2009.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025859026
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/j.pbi.2011.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051052998
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/j.semcdb.2012.01.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000712098
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/j.tplants.2004.07.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009906456
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1021/es070627i schema:sameAs https://app.dimensions.ai/details/publication/pub.1055500521
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1021/es802412r schema:sameAs https://app.dimensions.ai/details/publication/pub.1055515533
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1021/es802612a schema:sameAs https://app.dimensions.ai/details/publication/pub.1055515603
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1042/bc20040133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007245112
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1046/j.1469-8137.2003.00655.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003729595
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1073/pnas.0802361105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037637133
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1073/pnas.1013964107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013509562
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1073/pnas.1109127108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006106452
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1080/07853890310016324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008238857
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1093/dnares/dst011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004428714
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1093/jxb/ert143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027889262
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1093/nar/gkm259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053546100
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1093/pcp/pch202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010441240
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1093/pcp/pci172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005931501
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1104/pp.104.052423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041630038
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1104/pp.111.180893 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034333020
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1105/tpc.106.041871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036111940
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1105/tpc.106.048488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052662461
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1105/tpc.107.057380 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012231878
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1105/tpc.108.061994 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042113877
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1111/j.1365-313x.2007.03212.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022119873
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1111/j.1365-313x.2009.04109.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033819071
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1111/j.1365-313x.2011.04665.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001156143
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1111/j.1469-8137.2008.02716.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025319328
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1111/pce.12138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004114631
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1126/science.1072375 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062446603
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1126/science.1072896 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019045153
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1146/annurev.arplant.55.031903.141801 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019175008
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1146/annurev.arplant.59.032607.092734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012295811
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1146/annurev.cellbio.19.110701.154617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016222049
289 rdf:type schema:CreativeWork
290 https://doi.org/10.4161/psb.5.6.11425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072309313
291 rdf:type schema:CreativeWork
292 https://www.grid.ac/institutes/grid.289247.2 schema:alternateName Kyung Hee University
293 schema:name Department of Plant Environmental New Resources, KyungHee University, 446-701, Yongin, Republic of Korea
294 rdf:type schema:Organization
295 https://www.grid.ac/institutes/grid.412010.6 schema:alternateName Kangwon National University
296 schema:name Department of Biological Environment, Kangwon National University, 200-701, Chuncheon, Republic of Korea
297 Plant Genomics Lab, Department of Applied Plant Sciences, Kangwon National University, 200-713, Chuncheon, Republic of Korea
298 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...