Interplay among RNA polymerases II, IV and V in RNA-directed DNA methylation at a low copy transgene locus in Arabidopsis ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-03-20

AUTHORS

Wanhui You, Zdravko J. Lorkovic, Antonius J. M. Matzke, Marjori Matzke

ABSTRACT

RNA-directed DNA methylation (RdDM) is an epigenetic process whereby small interfering RNAs (siRNAs) guide cytosine methylation of homologous DNA sequences. RdDM requires two specialized RNA polymerases: Pol IV transcribes the siRNA precursor whereas Pol V generates scaffold RNAs that interact with siRNAs and attract the methylation machinery. Recent evidence also suggests the involvement of RNA polymerase II (Pol II) in recruiting Pol IV and Pol V to low copy, intergenic loci. We demonstrated previously that Pol V-mediated methylation at a transgene locus in Arabidopsis spreads downstream of the originally targeted region by means of Pol IV/RNA-DEPENDENT RNA POLYMERASE2 (RDR2)-dependent 24-nt secondary siRNAs. Here we show that these secondary siRNAs can not only induce methylation in cis but also in trans at an unlinked target site, provided this sequence is transcribed by Pol II to produce a non-coding RNA. The Pol II transcript appears to be important for amplification of siRNAs at the unlinked target site because its presence correlates not only with methylation but also with elevated levels of 24-nt siRNAs. Potential target sites that lack an overlapping Pol II transcript and remain unmethylated in the presence of trans-acting 24-nt siRNAs can nevertheless acquire methylation in the presence of 21–24-nt hairpin-derived siRNAs, suggesting that RdDM of non-transcribed target sequences requires multiple size classes of siRNA. Our findings demonstrate that Pol II transcripts are not always needed for RdDM at low copy loci but they may intensify RdDM by facilitating amplification of Pol IV-dependent siRNAs at the DNA target site. More... »

PAGES

85-96

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11103-013-0041-4

DOI

http://dx.doi.org/10.1007/s11103-013-0041-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048426334

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23512103


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arabidopsis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Pairing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blotting, Northern", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Methylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Directed RNA Polymerases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Dosage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Silencing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Loci", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Small Interfering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reverse Transcriptase Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transgenes", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.24194.3a", 
          "name": [
            "Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "You", 
        "givenName": "Wanhui", 
        "id": "sg:person.0721322302.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721322302.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, Zagreb, Croatia", 
          "id": "http://www.grid.ac/institutes/grid.4808.4", 
          "name": [
            "Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria", 
            "Department of Molecular Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, Zagreb, Croatia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lorkovic", 
        "givenName": "Zdravko J.", 
        "id": "sg:person.01117323165.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117323165.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.506932.b", 
          "name": [
            "Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria", 
            "Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matzke", 
        "givenName": "Antonius J. M.", 
        "id": "sg:person.0604170460.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604170460.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.506932.b", 
          "name": [
            "Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria", 
            "Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matzke", 
        "givenName": "Marjori", 
        "id": "sg:person.01366677656.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366677656.47"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00020010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019204523", 
          "https://doi.org/10.1007/bf00020010"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cr.2011.23", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004608477", 
          "https://doi.org/10.1038/cr.2011.23"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng2081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033768664", 
          "https://doi.org/10.1038/ng2081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00014672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007506198", 
          "https://doi.org/10.1007/bf00014672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020980808", 
          "https://doi.org/10.1038/ng.119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034310095", 
          "https://doi.org/10.1038/ng1580"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1746-4811-6-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027302611", 
          "https://doi.org/10.1186/1746-4811-6-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm3152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038476039", 
          "https://doi.org/10.1038/nrm3152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00032565", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039046390", 
          "https://doi.org/10.1007/bf00032565"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01969712", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002431148", 
          "https://doi.org/10.1007/bf01969712"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-03-20", 
    "datePublishedReg": "2013-03-20", 
    "description": "RNA-directed DNA methylation (RdDM) is an epigenetic process whereby small interfering RNAs (siRNAs) guide cytosine methylation of homologous DNA sequences. RdDM requires two specialized RNA polymerases: Pol IV transcribes the siRNA precursor whereas Pol V generates scaffold RNAs that interact with siRNAs and attract the methylation machinery. Recent evidence also suggests the involvement of RNA polymerase II (Pol II) in recruiting Pol IV and Pol V to low copy, intergenic loci. We demonstrated previously that Pol V-mediated methylation at a transgene locus in Arabidopsis spreads downstream of the originally targeted region by means of Pol IV/RNA-DEPENDENT RNA POLYMERASE2 (RDR2)-dependent 24-nt secondary siRNAs. Here we show that these secondary siRNAs can not only induce methylation in cis but also in trans at an unlinked target site, provided this sequence is transcribed by Pol II to produce a non-coding RNA. The Pol II transcript appears to be important for amplification of siRNAs at the unlinked target site because its presence correlates not only with methylation but also with elevated levels of 24-nt siRNAs. Potential target sites that lack an overlapping Pol II transcript and remain unmethylated in the presence of trans-acting 24-nt siRNAs can nevertheless acquire methylation in the presence of 21\u201324-nt hairpin-derived siRNAs, suggesting that RdDM of non-transcribed target sequences requires multiple size classes of siRNA. Our findings demonstrate that Pol II transcripts are not always needed for RdDM at low copy loci but they may intensify RdDM by facilitating amplification of Pol IV-dependent siRNAs at the DNA target site.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11103-013-0041-4", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.7580451", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1101246", 
        "issn": [
          "0167-4412", 
          "1573-5028"
        ], 
        "name": "Plant Molecular Biology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1-2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "82"
      }
    ], 
    "keywords": [
      "Pol II transcripts", 
      "RNA polymerase II", 
      "Pol V", 
      "secondary siRNAs", 
      "polymerase II", 
      "transgene loci", 
      "DNA methylation", 
      "Pol IV", 
      "RNA-DEPENDENT RNA POLYMERASE2", 
      "target site", 
      "IV-dependent siRNAs", 
      "specialized RNA polymerase", 
      "homologous DNA sequences", 
      "low-copy loci", 
      "DNA target sites", 
      "non-coding RNAs", 
      "Arabidopsis thaliana", 
      "methylation machinery", 
      "potential target sites", 
      "multiple size classes", 
      "intergenic loci", 
      "cytosine methylation", 
      "scaffold RNAs", 
      "siRNA precursors", 
      "Pol II", 
      "RNA polymerase", 
      "epigenetic processes", 
      "DNA sequences", 
      "RdDM", 
      "methylation", 
      "RNA", 
      "siRNAs", 
      "loci", 
      "target sequence", 
      "transcripts", 
      "size classes", 
      "low copy", 
      "sequence", 
      "Recent evidence", 
      "Arabidopsis", 
      "thaliana", 
      "sites", 
      "polymerase", 
      "machinery", 
      "amplification", 
      "elevated levels", 
      "siRNA", 
      "copies", 
      "Pol", 
      "presence", 
      "trans", 
      "interplay", 
      "precursors", 
      "region", 
      "involvement", 
      "evidence", 
      "levels", 
      "cis", 
      "process", 
      "findings", 
      "class", 
      "means"
    ], 
    "name": "Interplay among RNA polymerases II, IV and V in RNA-directed DNA methylation at a low copy transgene locus in Arabidopsis thaliana", 
    "pagination": "85-96", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048426334"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11103-013-0041-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23512103"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11103-013-0041-4", 
      "https://app.dimensions.ai/details/publication/pub.1048426334"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_590.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11103-013-0041-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11103-013-0041-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11103-013-0041-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11103-013-0041-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11103-013-0041-4'


 

This table displays all metadata directly associated to this object as RDF triples.

258 TRIPLES      21 PREDICATES      113 URIs      95 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11103-013-0041-4 schema:about N2fea8833d36946159e721183b5068ff6
2 N43b493fd7dfb42418df79823dd163612
3 N5bfbe30ddcce47a6b26905d7d8ddf62e
4 N5e0a3cc6310042ee82bb29c16d321e2f
5 N630b0a413ea04bd7ac9560b535c63b26
6 N6bb02cdc8011474a9360dee8a43fec1e
7 N798ed7b1b24f4eceb78d4cce3a6ab55e
8 N7eebdfac87914f47a9e467e8138cd30f
9 N8e472b3cb64b4c64b07ff505f27602bc
10 N92717e04de1c4b22a6b480e86f05bd1f
11 N945f43ddd16b4ba2a6d16edd3541964d
12 Nadf4524ba68a47b7a3f9cac43d204428
13 Nc4e31dc8b9d84842ab6d7d53ea5eb325
14 Nd60eaedb317a40ff898c1b396f33db25
15 Ndd8aee4209c74997b2fb67c3e9dc5d1c
16 Ne9e5421b6ba447bc844c75729326f1c0
17 anzsrc-for:06
18 anzsrc-for:0604
19 schema:author Nbd12479c7e214e9496cde52ba8a727fc
20 schema:citation sg:pub.10.1007/bf00014672
21 sg:pub.10.1007/bf00020010
22 sg:pub.10.1007/bf00032565
23 sg:pub.10.1007/bf01969712
24 sg:pub.10.1038/cr.2011.23
25 sg:pub.10.1038/ng.119
26 sg:pub.10.1038/ng1580
27 sg:pub.10.1038/ng2081
28 sg:pub.10.1038/nrm3152
29 sg:pub.10.1186/1746-4811-6-2
30 schema:datePublished 2013-03-20
31 schema:datePublishedReg 2013-03-20
32 schema:description RNA-directed DNA methylation (RdDM) is an epigenetic process whereby small interfering RNAs (siRNAs) guide cytosine methylation of homologous DNA sequences. RdDM requires two specialized RNA polymerases: Pol IV transcribes the siRNA precursor whereas Pol V generates scaffold RNAs that interact with siRNAs and attract the methylation machinery. Recent evidence also suggests the involvement of RNA polymerase II (Pol II) in recruiting Pol IV and Pol V to low copy, intergenic loci. We demonstrated previously that Pol V-mediated methylation at a transgene locus in Arabidopsis spreads downstream of the originally targeted region by means of Pol IV/RNA-DEPENDENT RNA POLYMERASE2 (RDR2)-dependent 24-nt secondary siRNAs. Here we show that these secondary siRNAs can not only induce methylation in cis but also in trans at an unlinked target site, provided this sequence is transcribed by Pol II to produce a non-coding RNA. The Pol II transcript appears to be important for amplification of siRNAs at the unlinked target site because its presence correlates not only with methylation but also with elevated levels of 24-nt siRNAs. Potential target sites that lack an overlapping Pol II transcript and remain unmethylated in the presence of trans-acting 24-nt siRNAs can nevertheless acquire methylation in the presence of 21–24-nt hairpin-derived siRNAs, suggesting that RdDM of non-transcribed target sequences requires multiple size classes of siRNA. Our findings demonstrate that Pol II transcripts are not always needed for RdDM at low copy loci but they may intensify RdDM by facilitating amplification of Pol IV-dependent siRNAs at the DNA target site.
33 schema:genre article
34 schema:isAccessibleForFree true
35 schema:isPartOf N7d08bff8e93c49d89da193d55ae05383
36 Nfd283c07dc2d463897c2c41ce48245b9
37 sg:journal.1101246
38 schema:keywords Arabidopsis
39 Arabidopsis thaliana
40 DNA methylation
41 DNA sequences
42 DNA target sites
43 IV-dependent siRNAs
44 Pol
45 Pol II
46 Pol II transcripts
47 Pol IV
48 Pol V
49 RNA
50 RNA polymerase
51 RNA polymerase II
52 RNA-DEPENDENT RNA POLYMERASE2
53 RdDM
54 Recent evidence
55 amplification
56 cis
57 class
58 copies
59 cytosine methylation
60 elevated levels
61 epigenetic processes
62 evidence
63 findings
64 homologous DNA sequences
65 intergenic loci
66 interplay
67 involvement
68 levels
69 loci
70 low copy
71 low-copy loci
72 machinery
73 means
74 methylation
75 methylation machinery
76 multiple size classes
77 non-coding RNAs
78 polymerase
79 polymerase II
80 potential target sites
81 precursors
82 presence
83 process
84 region
85 scaffold RNAs
86 secondary siRNAs
87 sequence
88 siRNA
89 siRNA precursors
90 siRNAs
91 sites
92 size classes
93 specialized RNA polymerase
94 target sequence
95 target site
96 thaliana
97 trans
98 transcripts
99 transgene loci
100 schema:name Interplay among RNA polymerases II, IV and V in RNA-directed DNA methylation at a low copy transgene locus in Arabidopsis thaliana
101 schema:pagination 85-96
102 schema:productId N0e5473e7054b4844bf20131d96a6bea0
103 N1c896474cab84edfb49608c1c1b4311a
104 Nd6fec298c8c04bbc8e1e4ef366144039
105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048426334
106 https://doi.org/10.1007/s11103-013-0041-4
107 schema:sdDatePublished 2022-12-01T06:30
108 schema:sdLicense https://scigraph.springernature.com/explorer/license/
109 schema:sdPublisher Nbd93a478e4f742ce85f49082675b038e
110 schema:url https://doi.org/10.1007/s11103-013-0041-4
111 sgo:license sg:explorer/license/
112 sgo:sdDataset articles
113 rdf:type schema:ScholarlyArticle
114 N0e5473e7054b4844bf20131d96a6bea0 schema:name doi
115 schema:value 10.1007/s11103-013-0041-4
116 rdf:type schema:PropertyValue
117 N1c896474cab84edfb49608c1c1b4311a schema:name pubmed_id
118 schema:value 23512103
119 rdf:type schema:PropertyValue
120 N2fea8833d36946159e721183b5068ff6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Arabidopsis
122 rdf:type schema:DefinedTerm
123 N43b493fd7dfb42418df79823dd163612 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Gene Silencing
125 rdf:type schema:DefinedTerm
126 N5bfbe30ddcce47a6b26905d7d8ddf62e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name RNA, Plant
128 rdf:type schema:DefinedTerm
129 N5e0a3cc6310042ee82bb29c16d321e2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Base Pairing
131 rdf:type schema:DefinedTerm
132 N630b0a413ea04bd7ac9560b535c63b26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Blotting, Northern
134 rdf:type schema:DefinedTerm
135 N6bb02cdc8011474a9360dee8a43fec1e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Models, Genetic
137 rdf:type schema:DefinedTerm
138 N798ed7b1b24f4eceb78d4cce3a6ab55e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Mutation
140 rdf:type schema:DefinedTerm
141 N7d08bff8e93c49d89da193d55ae05383 schema:issueNumber 1-2
142 rdf:type schema:PublicationIssue
143 N7eebdfac87914f47a9e467e8138cd30f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Gene Expression Regulation, Plant
145 rdf:type schema:DefinedTerm
146 N8a0039e0fe2246c0a07fbf55a1c16b57 rdf:first sg:person.0604170460.05
147 rdf:rest N907d74736ead45fbb205b2fcc02ebcce
148 N8e472b3cb64b4c64b07ff505f27602bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Transgenes
150 rdf:type schema:DefinedTerm
151 N907d74736ead45fbb205b2fcc02ebcce rdf:first sg:person.01366677656.47
152 rdf:rest rdf:nil
153 N92717e04de1c4b22a6b480e86f05bd1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name DNA-Directed RNA Polymerases
155 rdf:type schema:DefinedTerm
156 N945f43ddd16b4ba2a6d16edd3541964d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Gene Dosage
158 rdf:type schema:DefinedTerm
159 Nadf4524ba68a47b7a3f9cac43d204428 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name RNA, Small Interfering
161 rdf:type schema:DefinedTerm
162 Nbd12479c7e214e9496cde52ba8a727fc rdf:first sg:person.0721322302.31
163 rdf:rest Nc6f3a7bcacba4ded9604d0b9abd011b0
164 Nbd93a478e4f742ce85f49082675b038e schema:name Springer Nature - SN SciGraph project
165 rdf:type schema:Organization
166 Nc4e31dc8b9d84842ab6d7d53ea5eb325 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Genetic Loci
168 rdf:type schema:DefinedTerm
169 Nc6f3a7bcacba4ded9604d0b9abd011b0 rdf:first sg:person.01117323165.37
170 rdf:rest N8a0039e0fe2246c0a07fbf55a1c16b57
171 Nd60eaedb317a40ff898c1b396f33db25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name DNA Methylation
173 rdf:type schema:DefinedTerm
174 Nd6fec298c8c04bbc8e1e4ef366144039 schema:name dimensions_id
175 schema:value pub.1048426334
176 rdf:type schema:PropertyValue
177 Ndd8aee4209c74997b2fb67c3e9dc5d1c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Reverse Transcriptase Polymerase Chain Reaction
179 rdf:type schema:DefinedTerm
180 Ne9e5421b6ba447bc844c75729326f1c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name RNA, Messenger
182 rdf:type schema:DefinedTerm
183 Nfd283c07dc2d463897c2c41ce48245b9 schema:volumeNumber 82
184 rdf:type schema:PublicationVolume
185 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
186 schema:name Biological Sciences
187 rdf:type schema:DefinedTerm
188 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
189 schema:name Genetics
190 rdf:type schema:DefinedTerm
191 sg:grant.7580451 http://pending.schema.org/fundedItem sg:pub.10.1007/s11103-013-0041-4
192 rdf:type schema:MonetaryGrant
193 sg:journal.1101246 schema:issn 0167-4412
194 1573-5028
195 schema:name Plant Molecular Biology
196 schema:publisher Springer Nature
197 rdf:type schema:Periodical
198 sg:person.01117323165.37 schema:affiliation grid-institutes:grid.4808.4
199 schema:familyName Lorkovic
200 schema:givenName Zdravko J.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117323165.37
202 rdf:type schema:Person
203 sg:person.01366677656.47 schema:affiliation grid-institutes:grid.506932.b
204 schema:familyName Matzke
205 schema:givenName Marjori
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366677656.47
207 rdf:type schema:Person
208 sg:person.0604170460.05 schema:affiliation grid-institutes:grid.506932.b
209 schema:familyName Matzke
210 schema:givenName Antonius J. M.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604170460.05
212 rdf:type schema:Person
213 sg:person.0721322302.31 schema:affiliation grid-institutes:grid.24194.3a
214 schema:familyName You
215 schema:givenName Wanhui
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721322302.31
217 rdf:type schema:Person
218 sg:pub.10.1007/bf00014672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007506198
219 https://doi.org/10.1007/bf00014672
220 rdf:type schema:CreativeWork
221 sg:pub.10.1007/bf00020010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019204523
222 https://doi.org/10.1007/bf00020010
223 rdf:type schema:CreativeWork
224 sg:pub.10.1007/bf00032565 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039046390
225 https://doi.org/10.1007/bf00032565
226 rdf:type schema:CreativeWork
227 sg:pub.10.1007/bf01969712 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002431148
228 https://doi.org/10.1007/bf01969712
229 rdf:type schema:CreativeWork
230 sg:pub.10.1038/cr.2011.23 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004608477
231 https://doi.org/10.1038/cr.2011.23
232 rdf:type schema:CreativeWork
233 sg:pub.10.1038/ng.119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020980808
234 https://doi.org/10.1038/ng.119
235 rdf:type schema:CreativeWork
236 sg:pub.10.1038/ng1580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034310095
237 https://doi.org/10.1038/ng1580
238 rdf:type schema:CreativeWork
239 sg:pub.10.1038/ng2081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033768664
240 https://doi.org/10.1038/ng2081
241 rdf:type schema:CreativeWork
242 sg:pub.10.1038/nrm3152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038476039
243 https://doi.org/10.1038/nrm3152
244 rdf:type schema:CreativeWork
245 sg:pub.10.1186/1746-4811-6-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027302611
246 https://doi.org/10.1186/1746-4811-6-2
247 rdf:type schema:CreativeWork
248 grid-institutes:grid.24194.3a schema:alternateName Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria
249 schema:name Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria
250 rdf:type schema:Organization
251 grid-institutes:grid.4808.4 schema:alternateName Department of Molecular Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, Zagreb, Croatia
252 schema:name Department of Molecular Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, Zagreb, Croatia
253 Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria
254 rdf:type schema:Organization
255 grid-institutes:grid.506932.b schema:alternateName Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan
256 schema:name Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030, Vienna, Austria
257 Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, 115, Taipei, Taiwan
258 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...