Nanotechnology: Intelligent Design to Treat Complex Disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-07

AUTHORS

Patrick Couvreur, Christine Vauthier

ABSTRACT

The purpose of this expert review is to discuss the impact of nanotechnology in the treatment of the major health threats including cancer, infections, metabolic diseases, autoimmune diseases, and inflammations. Indeed, during the past 30 years, the explosive growth of nanotechnology has burst into challenging innovations in pharmacology, the main input being the ability to perform temporal and spatial site-specific delivery. This has led to some marketed compounds through the last decade. Although the introduction of nanotechnology obviously permitted to step over numerous milestones toward the development of the "magic bullet" proposed a century ago by the immunologist Paul Ehrlich, there are, however, unresolved delivery problems to be still addressed. These scientific and technological locks are discussed along this review together with an analysis of the current situation concerning the industrial development. More... »

PAGES

1417-1450

References to SciGraph publications

  • 1998-04. Drug Targeting by Polyalkylcyanoacrylate Nanoparticles Is Not Efficient Against Persistent Salmonella in PHARMACEUTICAL RESEARCH
  • 1991-01. Jejunal Absorption, Pharmacological Activity, and Pharmacokinetic Evaluation of Indomethacin-Loaded Poly(d,l-Lactide) and Poly(Isobutyl-Cyanoacrylate) Nanocapsules in Rats in PHARMACEUTICAL RESEARCH
  • 2001-12. Harnessing the Immune System for Neuroprotection: Therapeutic Vaccines for Acute and Chronic Neurodegenerative Disorders in CELLULAR AND MOLECULAR NEUROBIOLOGY
  • 2003-01. Influence of Spacer Length on Interaction of Mannosylated Liposomes with Human Phagocytic Cells in PHARMACEUTICAL RESEARCH
  • 2001-06. Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives in GENE THERAPY
  • 2004-04. Calcitonin Therapy in Osteoporosis in TREATMENTS IN ENDOCRINOLOGY
  • 1999-11. Ability of Doxorubicin-Loaded Nanoparticles to Overcome Multidrug Resistance of Tumor Cells After Their Capture by Macrophages in PHARMACEUTICAL RESEARCH
  • 2002-06. Recent Advances in Vaccine Adjuvants in PHARMACEUTICAL RESEARCH
  • 1997-03. Biologically erodable microspheres as potential oral drug delivery systems in NATURE
  • 2002-03. Use of the Post-Insertion Technique to Insert Peptide Ligands into Pre-Formed Stealth Liposomes with Retention of Binding Activity and Cytotoxicity in PHARMACEUTICAL RESEARCH
  • 1998-11. Altered Tissue Distribution and Elimination of Amikacin Encapsulated in Unilamellar, Low-Clearance Liposomes (MiKasome®) in PHARMACEUTICAL RESEARCH
  • 1995-06. The Fate of Plasmid DNA After Intravenous Injection in Mice: Involvement of Scavenger Receptors in Its Hepatic Uptake in PHARMACEUTICAL RESEARCH
  • 1992-06. Macrophage Activation by Polymeric Nanoparticles of Polyalkylcyanoacrylates: Activity Against Intracellular Leishmania donovani Associated with Hydrogen Peroxide Production in PHARMACEUTICAL RESEARCH
  • 2003-07. Visualization of Insulin-Loaded Nanocapsules: In Vitro and in Vivo Studies After Oral Administration to Rats in PHARMACEUTICAL RESEARCH
  • 2003-03. Antitumor Activity of Folate Receptor-Targeted Liposomal Doxorubicin in a KB Oral Carcinoma Murine Xenograft Model in PHARMACEUTICAL RESEARCH
  • 1997-02. Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation in NATURE MEDICINE
  • 1993-03. Phase I and pharmacokinetic trial of liposome-encapsulated doxorubicin in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2002-07. Genetic Immunization Using Nanoparticles Engineered from Microemulsion Precursors in PHARMACEUTICAL RESEARCH
  • 2004-04. The Characteristics and Mechanisms of Uptake of PLGA Nanoparticles in Rabbit Conjunctival Epithelial Cell Layers in PHARMACEUTICAL RESEARCH
  • 1993-05. Influence of Poly(DL-Lactide) Nanocapsules on the Biliary Clearance and Enterohepatic Circulation of Indomethacin in the Rabbit in PHARMACEUTICAL RESEARCH
  • 2003-10. Oligonucleotides Targeted Against a Junction Oncogene Are Made Efficient by Nanotechnologies in PHARMACEUTICAL RESEARCH
  • 2004-12. Foreign Particles Testing in Orally Inhaled and Nasal Drug Products in PHARMACEUTICAL RESEARCH
  • 2001-03. Formulation and Evaluation of a Folic Acid Receptor-Targeted Oral Vancomycin Liposomal Dosage Form in PHARMACEUTICAL RESEARCH
  • 2004-06. Nasal route and drug delivery systems in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
  • 2005-02. Recent advances with liposomes as pharmaceutical carriers in NATURE REVIEWS DRUG DISCOVERY
  • 2001-12. Strategies for designing and optimizing new generation vaccines in NATURE REVIEWS IMMUNOLOGY
  • 1994-09. Adsorption of Oligonucleotides onto Polyisohexylcyanoacrylate Nanoparticles Protects Them Against Nucleases and Increases Their Cellular Uptake in PHARMACEUTICAL RESEARCH
  • 2004-09. Novel Approaches to Vaccine Delivery in PHARMACEUTICAL RESEARCH
  • 2005-11. Insulin Containing Nanocomplexes Formed by Self-Assembly from Biodegradable Amine-Modified Poly(Vinyl Alcohol)-Graft-Poly(l-Lactide): Bioavailability and Nasal Tolerability in Rats in PHARMACEUTICAL RESEARCH
  • 2003-08. Interaction of Differently Designed Immunoliposomes with Colon Cancer Cells and Kupffer Cells. An in Vitro Comparison in PHARMACEUTICAL RESEARCH
  • 1995-10. Poly(D,L-Lactide) Nanocapsules Containing Non-Steroidal Anti-Inflammatory Drugs: Gastrointestinal Tolerance Following Intravenous and Oral Administration in PHARMACEUTICAL RESEARCH
  • 2005-01. Drug transport to brain with targeted nanoparticles in NEUROTHERAPEUTICS
  • 1997-03. The Oral Absorption of Micro- and Nanoparticulates: Neither Exceptional Nor Unusual in PHARMACEUTICAL RESEARCH
  • 2001-08. Inhibition of HIV-1 in Cell Culture by Oligonucleotide-Loaded Nanoparticles in PHARMACEUTICAL RESEARCH
  • 2003-01. Colloidal drug carriers: achievements and perspectives in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2005-12. Uptake and Transport of PEG-Graft-Trimethyl-Chitosan Copolymer–Insulin Nanocomplexes by Epithelial Cells in PHARMACEUTICAL RESEARCH
  • 1990-05. Hepatic tissue distribution of doxorubicin-loaded nanoparticles after i.v. administration in reticulosarcoma M 5076 metastasis-bearing mice in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 1998-07. Long-Circulating Nanopartides Bearing Heparin or Dextran Covalently Bound to Poly(Methyl Methacrylate) in PHARMACEUTICAL RESEARCH
  • 2005-04. Lipid based particulate formulations for the delivery of antigen in IMMUNOLOGY AND CELL BIOLOGY
  • 1997-07. Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action in BRITISH JOURNAL OF CANCER
  • 1997. Use of Magnetic Nanoparticles for Thermolysis of Cells in a Ferrofluid in SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS
  • 2001-04. Targeting of 3′-Azido 3′-Deoxythymidine (AZT)-Loaded Poly(Isohexylcyanoacrylate) Nanospheres to the Gastrointestinal Mucosa and Associated Lymphoid Tissues in PHARMACEUTICAL RESEARCH
  • 1996-01. Effects of Phospholipid Chain Length, Concentration, Charge, and Vesicle Size on Pulmonary Insulin Absorption in PHARMACEUTICAL RESEARCH
  • 1997. Magnetic Fluid Hyperthermia (MFH) in SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS
  • 2001-03. Tetanus Toxoid Loaded Nanoparticles from Sulfobutylated Poly(Vinyl Alcohol)-Graft-Poly(Lactide-co-Glycolide): Evaluation of Antibody Response After Oral and Nasal Application in Mice in PHARMACEUTICAL RESEARCH
  • 2003-07. CpG motifs: the active ingredient in bacterial extracts? in NATURE MEDICINE
  • 2000-06. Biovector™ Nanoparticles Improve Antinociceptive Efficacy of Nasal Morphine in PHARMACEUTICAL RESEARCH
  • 2002-08. Comparative Uptake Studies of Bioadhesive and Non-Bioadhesive Nanoparticles in Human Intestinal Cell Lines and Rats: The Effect of Mucus on Particle Adsorption and Transport in PHARMACEUTICAL RESEARCH
  • 2004-12. Mucosal adjuvants and delivery systems for protein-, DNA- and RNA-based vaccines in IMMUNOLOGY AND CELL BIOLOGY
  • 1995. Nanoparticles as Adjuvants for Vaccines in VACCINE DESIGN
  • 1991-09. Intranasal Salmon Calcitonin in DRUGS & AGING
  • 2001-07. Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo in PHARMACEUTICAL RESEARCH
  • 2002-10. Folate Receptor-Mediated Liposomal Delivery of a Lipophilic Boron Agent to Tumor Cells in Vitro for Neutron Capture Therapy in PHARMACEUTICAL RESEARCH
  • 1999-10. Enhancement of Nasal Absorption of Insulin Using Chitosan Nanoparticles in PHARMACEUTICAL RESEARCH
  • 1993-10. Inhibition of the Friend Retrovirus by Antisense Oligonucleotides Encapsulated in Liposomes: Mechanism of Action in PHARMACEUTICAL RESEARCH
  • 1990. Streptozotocin Interactions with Pancreatic β Cells and the Induction of Insulin-Dependent Diabetes in THE ROLE OF VIRUSES AND THE IMMUNE SYSTEM IN DIABETES MELLITUS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11095-006-0284-8

    DOI

    http://dx.doi.org/10.1007/s11095-006-0284-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006743812

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16779701


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