Search for Bactericides Among Derivatives of Deoxyvasicinone, Mackinazolinone, and Thienopyrimidinones View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-09

AUTHORS

I. S. Ortikov, Zh. É. Turdibaev, Zh. I. Islamova, B. Zh. Élmuradov, A. Sh. Abdurazakov, A. M. Bektemirov, S. O. Osipova, Z. A. Khushbaktova, V. N. Syrov, Kh. M. Shakhidoyatov

ABSTRACT

Series of arylidene- and arylhydroxymethyl derivatives of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-one and 2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-one were synthesized. Schiff bases were synthesized from amine derivatives. Hydroxymethylidene derivatives and arylaminomethylidene-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-ones and -2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-ones were obtained. The antimicrobial activity of the synthesized compounds against S. aureus, E. coli, Bacillus cereus, Candida albicans, and Pseudomonas aeruginosa was studied. It was concluded that the search for bactericides in these series was promising. More... »

PAGES

456-464

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11094-017-1633-0

DOI

http://dx.doi.org/10.1007/s11094-017-1633-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1092166566


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