Synthesis of Betulin Derivatives: N’{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-11

AUTHORS

S. V. Sysolyatin, V. N. Surmachev, V. V. Malykhin, A. I. Kalashnikov, I. A. Surmacheva, E. G. Sonina, A. S. Dubkov, G. A. Tolstikov, E. E. Shul’ts, N. F. Salakhutdinov, U. M. Dzhemilev

ABSTRACT

A method for synthesizing N’-{N-[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N-(9-aminononanoyl)-3-amino-3-phenylpropionic acid to betulonic acid was described.

PAGES

473-477

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11094-012-0828-7

DOI

http://dx.doi.org/10.1007/s11094-012-0828-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006334990


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sysolyatin", 
        "givenName": "S. V.", 
        "id": "sg:person.0627734065.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627734065.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Surmachev", 
        "givenName": "V. N.", 
        "id": "sg:person.016171455422.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016171455422.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Malykhin", 
        "givenName": "V. V.", 
        "id": "sg:person.016264402743.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016264402743.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kalashnikov", 
        "givenName": "A. I.", 
        "id": "sg:person.012607147014.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012607147014.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Surmacheva", 
        "givenName": "I. A.", 
        "id": "sg:person.0744162465.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744162465.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sonina", 
        "givenName": "E. G.", 
        "id": "sg:person.011705766407.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011705766407.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dubkov", 
        "givenName": "A. S.", 
        "id": "sg:person.010035772763.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010035772763.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.415877.8", 
          "name": [
            "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tolstikov", 
        "givenName": "G. A.", 
        "id": "sg:person.0727206551.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727206551.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.415877.8", 
          "name": [
            "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shul\u2019ts", 
        "givenName": "E. E.", 
        "id": "sg:person.0677615503.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677615503.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia", 
          "id": "http://www.grid.ac/institutes/grid.415877.8", 
          "name": [
            "Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salakhutdinov", 
        "givenName": "N. F.", 
        "id": "sg:person.01334707733.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334707733.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 450075, Bashkortostan, Ufa, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 450075, Bashkortostan, Ufa, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dzhemilev", 
        "givenName": "U. M.", 
        "id": "sg:person.011637315036.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011637315036.37"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2012-11", 
    "datePublishedReg": "2012-11-01", 
    "description": "A method for synthesizing N\u2019-{N-[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N-(9-aminononanoyl)-3-amino-3-phenylpropionic acid to betulonic acid was described.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11094-012-0828-7", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1371981", 
        "issn": [
          "0091-150X", 
          "1573-9031"
        ], 
        "name": "Pharmaceutical Chemistry Journal", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "46"
      }
    ], 
    "keywords": [
      "antiviral activity", 
      "amino-3-phenylpropionic acid", 
      "betulonic acid", 
      "betulin derivatives", 
      "immunostimulating", 
      "methyl ester", 
      "acid", 
      "activity", 
      "esters", 
      "compounds", 
      "derivatives", 
      "method", 
      "oxo", 
      "synthesis", 
      "ns"
    ], 
    "name": "Synthesis of Betulin Derivatives: N\u2019{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid", 
    "pagination": "473-477", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006334990"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11094-012-0828-7"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11094-012-0828-7", 
      "https://app.dimensions.ai/details/publication/pub.1006334990"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_581.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11094-012-0828-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11094-012-0828-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11094-012-0828-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11094-012-0828-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11094-012-0828-7'


 

This table displays all metadata directly associated to this object as RDF triples.

147 TRIPLES      20 PREDICATES      40 URIs      32 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11094-012-0828-7 schema:about anzsrc-for:11
2 anzsrc-for:1115
3 schema:author Nb7c31148bbe54beea6d4ac9f3a9aa841
4 schema:datePublished 2012-11
5 schema:datePublishedReg 2012-11-01
6 schema:description A method for synthesizing N’-{N-[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N-(9-aminononanoyl)-3-amino-3-phenylpropionic acid to betulonic acid was described.
7 schema:genre article
8 schema:isAccessibleForFree false
9 schema:isPartOf N64c8cffb0e6c4c8aa09880dedfee7dc1
10 N85e29c28f60f432c8221a38a51a0202b
11 sg:journal.1371981
12 schema:keywords acid
13 activity
14 amino-3-phenylpropionic acid
15 antiviral activity
16 betulin derivatives
17 betulonic acid
18 compounds
19 derivatives
20 esters
21 immunostimulating
22 method
23 methyl ester
24 ns
25 oxo
26 synthesis
27 schema:name Synthesis of Betulin Derivatives: N’{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid
28 schema:pagination 473-477
29 schema:productId N96a55bd38e5b48be8f2faecc1e717640
30 Ne06690ae54b24530a9c5a5a6aafaecc2
31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006334990
32 https://doi.org/10.1007/s11094-012-0828-7
33 schema:sdDatePublished 2022-12-01T06:30
34 schema:sdLicense https://scigraph.springernature.com/explorer/license/
35 schema:sdPublisher N0c4e8f3d58814eeeafc0e18c0b43395b
36 schema:url https://doi.org/10.1007/s11094-012-0828-7
37 sgo:license sg:explorer/license/
38 sgo:sdDataset articles
39 rdf:type schema:ScholarlyArticle
40 N0c4e8f3d58814eeeafc0e18c0b43395b schema:name Springer Nature - SN SciGraph project
41 rdf:type schema:Organization
42 N13d8c4b4822d497bb0da3d11f38bfd2b rdf:first sg:person.010035772763.42
43 rdf:rest N282cb8eda31d4af4ad18ecbc020cd71b
44 N282cb8eda31d4af4ad18ecbc020cd71b rdf:first sg:person.0727206551.97
45 rdf:rest N4ee7dd893e8b4600a623469a0a140d40
46 N2c88455aa6844ffb8495f6918d859646 rdf:first sg:person.0744162465.09
47 rdf:rest N968f49c17d1745bb9c46f60b28da90ec
48 N2ff585f3210f4dc79a10b5ce391bc3a9 rdf:first sg:person.01334707733.11
49 rdf:rest N60a8f2c5b7df481090284d014c612999
50 N3a76db96a32f4e67b2cb0f0a4db4cb47 rdf:first sg:person.016171455422.97
51 rdf:rest N99b5ce476bd848658d90f30ef48f45ff
52 N4ee7dd893e8b4600a623469a0a140d40 rdf:first sg:person.0677615503.12
53 rdf:rest N2ff585f3210f4dc79a10b5ce391bc3a9
54 N60a8f2c5b7df481090284d014c612999 rdf:first sg:person.011637315036.37
55 rdf:rest rdf:nil
56 N64c8cffb0e6c4c8aa09880dedfee7dc1 schema:volumeNumber 46
57 rdf:type schema:PublicationVolume
58 N85e29c28f60f432c8221a38a51a0202b schema:issueNumber 8
59 rdf:type schema:PublicationIssue
60 N968f49c17d1745bb9c46f60b28da90ec rdf:first sg:person.011705766407.33
61 rdf:rest N13d8c4b4822d497bb0da3d11f38bfd2b
62 N96a55bd38e5b48be8f2faecc1e717640 schema:name dimensions_id
63 schema:value pub.1006334990
64 rdf:type schema:PropertyValue
65 N99b5ce476bd848658d90f30ef48f45ff rdf:first sg:person.016264402743.33
66 rdf:rest Na58713fedc604a4fb75dcfb9bee42969
67 Na58713fedc604a4fb75dcfb9bee42969 rdf:first sg:person.012607147014.10
68 rdf:rest N2c88455aa6844ffb8495f6918d859646
69 Nb7c31148bbe54beea6d4ac9f3a9aa841 rdf:first sg:person.0627734065.77
70 rdf:rest N3a76db96a32f4e67b2cb0f0a4db4cb47
71 Ne06690ae54b24530a9c5a5a6aafaecc2 schema:name doi
72 schema:value 10.1007/s11094-012-0828-7
73 rdf:type schema:PropertyValue
74 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
75 schema:name Medical and Health Sciences
76 rdf:type schema:DefinedTerm
77 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
78 schema:name Pharmacology and Pharmaceutical Sciences
79 rdf:type schema:DefinedTerm
80 sg:journal.1371981 schema:issn 0091-150X
81 1573-9031
82 schema:name Pharmaceutical Chemistry Journal
83 schema:publisher Springer Nature
84 rdf:type schema:Periodical
85 sg:person.010035772763.42 schema:affiliation grid-institutes:grid.4886.2
86 schema:familyName Dubkov
87 schema:givenName A. S.
88 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010035772763.42
89 rdf:type schema:Person
90 sg:person.011637315036.37 schema:affiliation grid-institutes:grid.4886.2
91 schema:familyName Dzhemilev
92 schema:givenName U. M.
93 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011637315036.37
94 rdf:type schema:Person
95 sg:person.011705766407.33 schema:affiliation grid-institutes:grid.4886.2
96 schema:familyName Sonina
97 schema:givenName E. G.
98 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011705766407.33
99 rdf:type schema:Person
100 sg:person.012607147014.10 schema:affiliation grid-institutes:grid.4886.2
101 schema:familyName Kalashnikov
102 schema:givenName A. I.
103 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012607147014.10
104 rdf:type schema:Person
105 sg:person.01334707733.11 schema:affiliation grid-institutes:grid.415877.8
106 schema:familyName Salakhutdinov
107 schema:givenName N. F.
108 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334707733.11
109 rdf:type schema:Person
110 sg:person.016171455422.97 schema:affiliation grid-institutes:grid.4886.2
111 schema:familyName Surmachev
112 schema:givenName V. N.
113 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016171455422.97
114 rdf:type schema:Person
115 sg:person.016264402743.33 schema:affiliation grid-institutes:grid.4886.2
116 schema:familyName Malykhin
117 schema:givenName V. V.
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016264402743.33
119 rdf:type schema:Person
120 sg:person.0627734065.77 schema:affiliation grid-institutes:grid.4886.2
121 schema:familyName Sysolyatin
122 schema:givenName S. V.
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627734065.77
124 rdf:type schema:Person
125 sg:person.0677615503.12 schema:affiliation grid-institutes:grid.415877.8
126 schema:familyName Shul’ts
127 schema:givenName E. E.
128 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677615503.12
129 rdf:type schema:Person
130 sg:person.0727206551.97 schema:affiliation grid-institutes:grid.415877.8
131 schema:familyName Tolstikov
132 schema:givenName G. A.
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727206551.97
134 rdf:type schema:Person
135 sg:person.0744162465.09 schema:affiliation grid-institutes:grid.4886.2
136 schema:familyName Surmacheva
137 schema:givenName I. A.
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744162465.09
139 rdf:type schema:Person
140 grid-institutes:grid.415877.8 schema:alternateName Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia
141 schema:name Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia
142 rdf:type schema:Organization
143 grid-institutes:grid.4886.2 schema:alternateName Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia
144 Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 450075, Bashkortostan, Ufa, Russia
145 schema:name Institute for Problems of Chemical and Energy Technologies, Siberian Branch, Russian Academy of Sciences, 659322, Biisk, Russia
146 Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 450075, Bashkortostan, Ufa, Russia
147 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...