Synthesis and antiviral activity of new adamantane derivatives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-01

AUTHORS

I. K. Moiseev, S. A. Kon’kov, K. A. Ovchinnikov, N. M. Kilyaeva, K. M. Bormasheva, O. N. Nechaeva, M. V. Leonova, Yu. N. Klimochkin, S. M. Balakhnin, N. I. Bormotov, O. A. Serova, E. F. Belanov

ABSTRACT

New pyrazoles; 1,2,4-triazoles; β- and γ-glycols; amidrazones; and amines of the adamantane series have been synthesized. Their activity with respect to smallpox vaccine virus has been studied. High anti-smallpox activity was observed for ethyl-3-(1-adamantyl)-5-(4-methylphenyl)-1H-pyrazole-4-carboxylate (VI) and 1,4-bis(1-adamantyl)-1,4-butanediol (XII).

PAGES

588-592

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11094-012-0686-3

DOI

http://dx.doi.org/10.1007/s11094-012-0686-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032760768


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