Ontology type: schema:ScholarlyArticle
2009-08
AUTHORSN. A. Pulina, V. V. Zalesov, O. A. Bystritskaya, A. E. Rubtsov, N. V. Kutkovaya
ABSTRACTAseries of substituted 2-methylenehydrazino-4-aryl-4-oxobut-2-enoic acids and their anilides and esters were obtained using reactions of 4-aryl-2-hydroxy-4-oxobut-2-enoic acids and their amides and esters with benzophenone hydrazone, benzyl monohydrazone, and triphenylphosphazines. The methyl ester of 2-(1,2-diphenyl-2-oxoethylidenehydrazino)-4-(4-chlorophenyl)-4-oxobut-2-enoic acid was also synthesized by decyclization of 3-(1,2-diphenyl-2-oxoethylidenehydrazino)-5-(4-chlorophenyl)-3H-furan-2-one using methanol. The synthesized compounds exhibit moderate anti-inflammatory, analgesic, and antimicrobial activity. More... »
PAGES444
http://scigraph.springernature.com/pub.10.1007/s11094-009-0334-8
DOIhttp://dx.doi.org/10.1007/s11094-009-0334-8
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