Studies of synthesis routes for biologically active 14α-hydroxylated steroids View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-01

AUTHORS

V. V. Yaderets, V. A. Andryushina, N. E. Voishvillo, T. S. Stytsenko, O. A. Zeinalov

ABSTRACT

The conditions for preparing 14α-hydroxyandrostenedione - an intermediate in the synthesis of highly active gestagens - using the fungus Curvularia lunata CBE with an increased steroid substrate load of 5 g/liter in the presence of methylcyclodextrin were identified. The microbiological method of introducing 14α-hydroxy groups into the androstane structure has significant advantages over chemical approaches from the technical and ecological points of view and for obtaining a higher yield. More... »

PAGES

55-58

References to SciGraph publications

  • 2007-11. A study of steroid hydroxylation activity of Curvularia lunata mycelium in APPLIED BIOCHEMISTRY AND MICROBIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11094-009-0229-8

    DOI

    http://dx.doi.org/10.1007/s11094-009-0229-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023426482


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