Delayed development of a rhabdomyosarcoma following radiation for a spinal cord glioma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-03

AUTHORS

Edmond Mazbani, Robin L. Jones, James Fink, Marc C. Chamberlain

ABSTRACT

Radiation-induced sarcomas represent a rare delayed-late secondary complication of radiation therapy. Radiation-associated sarcomas are associated with a worse overall prognosis compared to sporadic sarcomas irrespective of histological type. Herein we report a case of a 65-year old man who underwent surgery and radiation therapy for a T4 spinal cord low-grade two astrocytoma in 1965 and presented over 40 years later with spinal cord complex intramedullary tumor involving the thoracic cord with drop metastases in the lumbar spine. Histology from a partial resection of the thoracic spinal tumor revealed a high-grade rhabdomyosarcoma. In addition to the rarity of radiation-induced sarcoma arising following the treatment of a spinal cord glioma, this case study represents one of the first reports of a spinal cord rhabdomyosarcoma arising in this setting. More... »

PAGES

115-118

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11060-012-1042-x

DOI

http://dx.doi.org/10.1007/s11060-012-1042-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029806596

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23296545


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161 Division of Neuro-Oncology, Department of Neurology and Neurological Surgery, University of Washington, Fred Hutchinson Research Cancer Center, Seattle Cancer Care Alliance, 825 Eastlake Ave E, MS G4940, PO Box 19023, 98109, Seattle, WA, USA
162 rdf:type schema:Organization
 




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