Surgical treatment of high-grade gliomas in motor areas. The impact of different supportive technologies: a 171-patient series View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-05-14

AUTHORS

Andrea Talacchi, Sergio Turazzi, Francesca Locatelli, Francesco Sala, Alberto Beltramello, Franco Alessandrini, Paolo Manganotti, Paola Lanteri, Roberta Gambin, Mario Ganau, Vincenzo Tramontano, Barbara Santini, Massimo Gerosa

ABSTRACT

In the last few years much has been published to validate new technology in brain mapping for clinical purposes, but there have been few clinical results. In this report we describe our five-year experience in the surgical management of malignant gliomas around motor areas with an evaluation of the impact of functional magnetic resonance imaging (fMRI) plus navigator and intraoperative neurophysiology (IN). End-points were extent of removal, morbidity, and survival. Variables describing patient and tumor characteristics and treatment modalities were statistically weighted in relation to treatment outcome. Tumor depth (P = 0.01), midline shift ≥1 cm. (P = 0.05), and insular location (P = 0.001) negatively affected extent of removal, whereas IN (P < 0.001) and fMRI plus navigator (P = 0.02) contributed to increasing the rate of total removal (73%, 71% vs. 40%). Postoperative motor impairment was mild and transient in a minority of cases (20%). General complications, as defined by the Glioma Outcome Project, occurred in 23% of cases. IN was the only factor associated with acute postoperative motor deterioration (P < 0.001). IN and age >65 years (P = 0.01) were associated with the occurrence of complications. Overall survival was significantly higher in patients operated with IN or fMRI plus navigator (P < 0.01). Comparing different surgical strategies used in the same period, we observed that supportive technologies in glioma surgery have their primary impact on the quality of resection and survival. IN led to transient motor impairment and some additional complications which did not affect functional outcome. More... »

PAGES

417-426

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11060-010-0193-x

DOI

http://dx.doi.org/10.1007/s11060-010-0193-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052916834

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20467787


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glioma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Image Processing, Computer-Assisted", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intraoperative Period", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Karnofsky Performance Status", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Motor Cortex", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Movement Disorders", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurosurgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Odds Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oxygen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Complications", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, P. Stefani 1, 37126, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, P. Stefani 1, 37126, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Talacchi", 
        "givenName": "Andrea", 
        "id": "sg:person.0604742273.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604742273.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neurosurgery, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Division of Neurosurgery, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Turazzi", 
        "givenName": "Sergio", 
        "id": "sg:person.0721656754.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721656754.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Epidemiology and Medical Statistics, Department of Hygiene and Public Health, University of Verona, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Section of Epidemiology and Medical Statistics, Department of Hygiene and Public Health, University of Verona, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Locatelli", 
        "givenName": "Francesca", 
        "id": "sg:person.013712032777.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013712032777.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sala", 
        "givenName": "Francesco", 
        "id": "sg:person.01060645151.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060645151.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neuroradiology, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Division of Neuroradiology, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beltramello", 
        "givenName": "Alberto", 
        "id": "sg:person.01261705110.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261705110.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neuroradiology, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Division of Neuroradiology, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alessandrini", 
        "givenName": "Franco", 
        "id": "sg:person.01031230110.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031230110.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurology, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurology, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Manganotti", 
        "givenName": "Paolo", 
        "id": "sg:person.01005557013.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005557013.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neurology, \u201cSacro Cuore\u201d Hospital, Negrar, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.416422.7", 
          "name": [
            "Division of Neurology, \u201cSacro Cuore\u201d Hospital, Negrar, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lanteri", 
        "givenName": "Paola", 
        "id": "sg:person.016054451775.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016054451775.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neurosurgery, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Division of Neurosurgery, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gambin", 
        "givenName": "Roberta", 
        "id": "sg:person.01301530520.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301530520.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ganau", 
        "givenName": "Mario", 
        "id": "sg:person.0752175503.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752175503.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tramontano", 
        "givenName": "Vincenzo", 
        "id": "sg:person.01170414104.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170414104.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santini", 
        "givenName": "Barbara", 
        "id": "sg:person.01330346373.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330346373.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.411475.2", 
          "name": [
            "Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gerosa", 
        "givenName": "Massimo", 
        "id": "sg:person.0612376172.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612376172.58"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00216-008-2443-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026887725", 
          "https://doi.org/10.1007/s00216-008-2443-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4899-3242-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1109705877", 
          "https://doi.org/10.1007/978-1-4899-3242-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01541777", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027860749", 
          "https://doi.org/10.1007/bf01541777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s007010070088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027942010", 
          "https://doi.org/10.1007/s007010070088"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-05-14", 
    "datePublishedReg": "2010-05-14", 
    "description": "In the last few years much has been published to validate new technology in brain mapping for clinical purposes, but there have been few clinical results. In this report we describe our five-year experience in the surgical management of malignant gliomas around motor areas with an evaluation of the impact of functional magnetic resonance imaging (fMRI) plus navigator and intraoperative neurophysiology (IN). End-points were extent of removal, morbidity, and survival. Variables describing patient and tumor characteristics and treatment modalities were statistically weighted in relation to treatment outcome. Tumor depth (P\u00a0=\u00a00.01), midline shift \u22651\u00a0cm. (P\u00a0=\u00a00.05), and insular location (P\u00a0=\u00a00.001) negatively affected extent of removal, whereas IN (P\u00a0<\u00a00.001) and fMRI plus navigator (P\u00a0=\u00a00.02) contributed to increasing the rate of total removal (73%, 71% vs. 40%). Postoperative motor impairment was mild and transient in a minority of cases (20%). General complications, as defined by the Glioma Outcome Project, occurred in 23% of cases. IN was the only factor associated with acute postoperative motor deterioration (P\u00a0<\u00a00.001). IN and age >65\u00a0years (P\u00a0=\u00a00.01) were associated with the occurrence of complications. Overall survival was significantly higher in patients operated with IN or fMRI plus navigator (P\u00a0<\u00a00.01). Comparing different surgical strategies used in the same period, we observed that supportive technologies in glioma surgery have their primary impact on the quality of resection and survival. IN led to transient motor impairment and some additional complications which did not affect functional outcome.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11060-010-0193-x", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1094205", 
        "issn": [
          "0167-594X", 
          "1573-7373"
        ], 
        "name": "Journal of Neuro-Oncology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "100"
      }
    ], 
    "keywords": [
      "functional magnetic resonance imaging", 
      "intraoperative neurophysiology", 
      "motor area", 
      "motor impairment", 
      "Glioma Outcomes Project", 
      "transient motor impairment", 
      "quality of resection", 
      "occurrence of complications", 
      "different surgical strategies", 
      "postoperative motor deterioration", 
      "high-grade gliomas", 
      "five-year experience", 
      "minority of cases", 
      "magnetic resonance imaging", 
      "general complications", 
      "overall survival", 
      "surgical treatment", 
      "surgical management", 
      "tumor characteristics", 
      "midline shift", 
      "surgical strategy", 
      "functional outcome", 
      "treatment modalities", 
      "clinical results", 
      "malignant gliomas", 
      "treatment outcomes", 
      "glioma surgery", 
      "tumor depth", 
      "motor deterioration", 
      "resonance imaging", 
      "Outcomes Project", 
      "complications", 
      "brain mapping", 
      "only factor", 
      "clinical purposes", 
      "survival", 
      "total removal", 
      "gliomas", 
      "impairment", 
      "additional complications", 
      "outcomes", 
      "same period", 
      "extent of removal", 
      "morbidity", 
      "resection", 
      "patients", 
      "surgery", 
      "years", 
      "insular locations", 
      "age", 
      "supportive technologies", 
      "modalities", 
      "treatment", 
      "neurophysiology", 
      "cases", 
      "report", 
      "imaging", 
      "navigator", 
      "removal", 
      "deterioration", 
      "extent", 
      "management", 
      "period", 
      "impact", 
      "factors", 
      "minority", 
      "evaluation", 
      "occurrence", 
      "rate", 
      "experience", 
      "area", 
      "primary impact", 
      "purpose", 
      "quality", 
      "strategies", 
      "variables", 
      "series", 
      "results", 
      "characteristics", 
      "location", 
      "new technologies", 
      "relation", 
      "shift", 
      "mapping", 
      "technology", 
      "project", 
      "depth"
    ], 
    "name": "Surgical treatment of high-grade gliomas in motor areas. The impact of different supportive technologies: a 171-patient series", 
    "pagination": "417-426", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1052916834"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11060-010-0193-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "20467787"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11060-010-0193-x", 
      "https://app.dimensions.ai/details/publication/pub.1052916834"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_516.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11060-010-0193-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11060-010-0193-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11060-010-0193-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11060-010-0193-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11060-010-0193-x'


 

This table displays all metadata directly associated to this object as RDF triples.

343 TRIPLES      22 PREDICATES      137 URIs      125 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11060-010-0193-x schema:about N0d509c42c40f4ea5822ebb9ef11729d7
2 N1ea0bfd676104bd3b4c69df3bae6e0d1
3 N239e1e7abe1d4aed8097de3516b319a6
4 N25f7eb6699804db899a0317a6daf12ad
5 N405654d55ee84cc09f347e1d9dd679e9
6 N4cc07079c9b14699ae373bd3901ef3b8
7 N5fa28a5c333042af9e21645efd504c74
8 N6bfac6eca895420bb92f14a502297da4
9 N6e5f07ca45444abf9f55f0ace4504343
10 N76601245d37344f988322cd71fe83fe1
11 N781468dd59b54bcbb61e3282d6198227
12 N7e398c8e9d684026b354376f6526ecab
13 Na4fa52c278e841d3b133962f11a070ae
14 Nd4e800c2529944069c7fc89bb65dca10
15 Nd842a2c1ab984a27b129a3487cd96e29
16 Nd8d9eb90a93d4c9f895ce5fa6fab9cf7
17 Ne05a7abe12654b3f87eb054a13a3624a
18 Nf46cf966944e4850a123b34c1861df6e
19 Nf584189baf414a3682f0ef2678b4e67a
20 Nfc76af6a61044cdb8427806aeef26296
21 anzsrc-for:11
22 anzsrc-for:1103
23 schema:author N0d1d99ee0cb34743abc8662c1bba2832
24 schema:citation sg:pub.10.1007/978-1-4899-3242-6
25 sg:pub.10.1007/bf01541777
26 sg:pub.10.1007/s00216-008-2443-8
27 sg:pub.10.1007/s007010070088
28 schema:datePublished 2010-05-14
29 schema:datePublishedReg 2010-05-14
30 schema:description In the last few years much has been published to validate new technology in brain mapping for clinical purposes, but there have been few clinical results. In this report we describe our five-year experience in the surgical management of malignant gliomas around motor areas with an evaluation of the impact of functional magnetic resonance imaging (fMRI) plus navigator and intraoperative neurophysiology (IN). End-points were extent of removal, morbidity, and survival. Variables describing patient and tumor characteristics and treatment modalities were statistically weighted in relation to treatment outcome. Tumor depth (P = 0.01), midline shift ≥1 cm. (P = 0.05), and insular location (P = 0.001) negatively affected extent of removal, whereas IN (P < 0.001) and fMRI plus navigator (P = 0.02) contributed to increasing the rate of total removal (73%, 71% vs. 40%). Postoperative motor impairment was mild and transient in a minority of cases (20%). General complications, as defined by the Glioma Outcome Project, occurred in 23% of cases. IN was the only factor associated with acute postoperative motor deterioration (P < 0.001). IN and age >65 years (P = 0.01) were associated with the occurrence of complications. Overall survival was significantly higher in patients operated with IN or fMRI plus navigator (P < 0.01). Comparing different surgical strategies used in the same period, we observed that supportive technologies in glioma surgery have their primary impact on the quality of resection and survival. IN led to transient motor impairment and some additional complications which did not affect functional outcome.
31 schema:genre article
32 schema:inLanguage en
33 schema:isAccessibleForFree false
34 schema:isPartOf Nc706c5308c5547a0b47af43cd7be1a7e
35 Nf1f75662db6e4a2cbb0681a0ff72455f
36 sg:journal.1094205
37 schema:keywords Glioma Outcomes Project
38 Outcomes Project
39 additional complications
40 age
41 area
42 brain mapping
43 cases
44 characteristics
45 clinical purposes
46 clinical results
47 complications
48 depth
49 deterioration
50 different surgical strategies
51 evaluation
52 experience
53 extent
54 extent of removal
55 factors
56 five-year experience
57 functional magnetic resonance imaging
58 functional outcome
59 general complications
60 glioma surgery
61 gliomas
62 high-grade gliomas
63 imaging
64 impact
65 impairment
66 insular locations
67 intraoperative neurophysiology
68 location
69 magnetic resonance imaging
70 malignant gliomas
71 management
72 mapping
73 midline shift
74 minority
75 minority of cases
76 modalities
77 morbidity
78 motor area
79 motor deterioration
80 motor impairment
81 navigator
82 neurophysiology
83 new technologies
84 occurrence
85 occurrence of complications
86 only factor
87 outcomes
88 overall survival
89 patients
90 period
91 postoperative motor deterioration
92 primary impact
93 project
94 purpose
95 quality
96 quality of resection
97 rate
98 relation
99 removal
100 report
101 resection
102 resonance imaging
103 results
104 same period
105 series
106 shift
107 strategies
108 supportive technologies
109 surgery
110 surgical management
111 surgical strategy
112 surgical treatment
113 survival
114 technology
115 total removal
116 transient motor impairment
117 treatment
118 treatment modalities
119 treatment outcomes
120 tumor characteristics
121 tumor depth
122 variables
123 years
124 schema:name Surgical treatment of high-grade gliomas in motor areas. The impact of different supportive technologies: a 171-patient series
125 schema:pagination 417-426
126 schema:productId N49c4e00b67bb41bd885b540ec7ef263e
127 Na7e6464f6eb14288b1e7c9ec2924348c
128 Nbc6f65de868342e88d57de01066169b1
129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052916834
130 https://doi.org/10.1007/s11060-010-0193-x
131 schema:sdDatePublished 2022-05-20T07:26
132 schema:sdLicense https://scigraph.springernature.com/explorer/license/
133 schema:sdPublisher Nca6d7ea2c0834f4aa8eea09b2195b75d
134 schema:url https://doi.org/10.1007/s11060-010-0193-x
135 sgo:license sg:explorer/license/
136 sgo:sdDataset articles
137 rdf:type schema:ScholarlyArticle
138 N0d1d99ee0cb34743abc8662c1bba2832 rdf:first sg:person.0604742273.27
139 rdf:rest N1aede926854d4c148270abb213586a4f
140 N0d509c42c40f4ea5822ebb9ef11729d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Female
142 rdf:type schema:DefinedTerm
143 N10bd4a42aedd4419a9e8b14e61ff695f rdf:first sg:person.013712032777.12
144 rdf:rest Necb699ee027b48aaabdf2534b08a41fc
145 N1aede926854d4c148270abb213586a4f rdf:first sg:person.0721656754.47
146 rdf:rest N10bd4a42aedd4419a9e8b14e61ff695f
147 N1ea0bfd676104bd3b4c69df3bae6e0d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Intraoperative Period
149 rdf:type schema:DefinedTerm
150 N239e1e7abe1d4aed8097de3516b319a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Male
152 rdf:type schema:DefinedTerm
153 N25f7eb6699804db899a0317a6daf12ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Glioma
155 rdf:type schema:DefinedTerm
156 N34596c94b27343e2a06a4cac9b15bf7b rdf:first sg:person.0612376172.58
157 rdf:rest rdf:nil
158 N3e41e960a74c4a32bc171d0338cbb1bc rdf:first sg:person.01301530520.96
159 rdf:rest Ndd2e0f9d396842e7a2927d0197e19342
160 N405654d55ee84cc09f347e1d9dd679e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Aged
162 rdf:type schema:DefinedTerm
163 N49c4e00b67bb41bd885b540ec7ef263e schema:name dimensions_id
164 schema:value pub.1052916834
165 rdf:type schema:PropertyValue
166 N4a92b4415d814fd2aab2587007d61ee9 rdf:first sg:person.016054451775.59
167 rdf:rest N3e41e960a74c4a32bc171d0338cbb1bc
168 N4cc07079c9b14699ae373bd3901ef3b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Motor Cortex
170 rdf:type schema:DefinedTerm
171 N4f6a209af71844d2a8256c1bbad2d189 rdf:first sg:person.01261705110.33
172 rdf:rest N856d2106b9534f67a179a531e6ea41c1
173 N520925b4b76f45e0899c363e73e7d296 rdf:first sg:person.01005557013.38
174 rdf:rest N4a92b4415d814fd2aab2587007d61ee9
175 N5fa28a5c333042af9e21645efd504c74 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Neurosurgical Procedures
177 rdf:type schema:DefinedTerm
178 N6bfac6eca895420bb92f14a502297da4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Image Processing, Computer-Assisted
180 rdf:type schema:DefinedTerm
181 N6e5f07ca45444abf9f55f0ace4504343 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Magnetic Resonance Imaging
183 rdf:type schema:DefinedTerm
184 N76601245d37344f988322cd71fe83fe1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Follow-Up Studies
186 rdf:type schema:DefinedTerm
187 N781468dd59b54bcbb61e3282d6198227 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Movement Disorders
189 rdf:type schema:DefinedTerm
190 N7a920a22bb2940e08146caf9bbcc0c57 rdf:first sg:person.01170414104.74
191 rdf:rest N9cfef082ac4a4214b6d68643f9e297a2
192 N7e398c8e9d684026b354376f6526ecab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Middle Aged
194 rdf:type schema:DefinedTerm
195 N856d2106b9534f67a179a531e6ea41c1 rdf:first sg:person.01031230110.69
196 rdf:rest N520925b4b76f45e0899c363e73e7d296
197 N9cfef082ac4a4214b6d68643f9e297a2 rdf:first sg:person.01330346373.09
198 rdf:rest N34596c94b27343e2a06a4cac9b15bf7b
199 Na4fa52c278e841d3b133962f11a070ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Postoperative Complications
201 rdf:type schema:DefinedTerm
202 Na7e6464f6eb14288b1e7c9ec2924348c schema:name pubmed_id
203 schema:value 20467787
204 rdf:type schema:PropertyValue
205 Nbc6f65de868342e88d57de01066169b1 schema:name doi
206 schema:value 10.1007/s11060-010-0193-x
207 rdf:type schema:PropertyValue
208 Nc706c5308c5547a0b47af43cd7be1a7e schema:issueNumber 3
209 rdf:type schema:PublicationIssue
210 Nca6d7ea2c0834f4aa8eea09b2195b75d schema:name Springer Nature - SN SciGraph project
211 rdf:type schema:Organization
212 Nd4e800c2529944069c7fc89bb65dca10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
213 schema:name Odds Ratio
214 rdf:type schema:DefinedTerm
215 Nd842a2c1ab984a27b129a3487cd96e29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
216 schema:name Oxygen
217 rdf:type schema:DefinedTerm
218 Nd8d9eb90a93d4c9f895ce5fa6fab9cf7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
219 schema:name Brain Neoplasms
220 rdf:type schema:DefinedTerm
221 Ndd2e0f9d396842e7a2927d0197e19342 rdf:first sg:person.0752175503.53
222 rdf:rest N7a920a22bb2940e08146caf9bbcc0c57
223 Ne05a7abe12654b3f87eb054a13a3624a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
224 schema:name Karnofsky Performance Status
225 rdf:type schema:DefinedTerm
226 Necb699ee027b48aaabdf2534b08a41fc rdf:first sg:person.01060645151.72
227 rdf:rest N4f6a209af71844d2a8256c1bbad2d189
228 Nf1f75662db6e4a2cbb0681a0ff72455f schema:volumeNumber 100
229 rdf:type schema:PublicationVolume
230 Nf46cf966944e4850a123b34c1861df6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
231 schema:name Treatment Outcome
232 rdf:type schema:DefinedTerm
233 Nf584189baf414a3682f0ef2678b4e67a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
234 schema:name Retrospective Studies
235 rdf:type schema:DefinedTerm
236 Nfc76af6a61044cdb8427806aeef26296 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
237 schema:name Humans
238 rdf:type schema:DefinedTerm
239 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
240 schema:name Medical and Health Sciences
241 rdf:type schema:DefinedTerm
242 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
243 schema:name Clinical Sciences
244 rdf:type schema:DefinedTerm
245 sg:journal.1094205 schema:issn 0167-594X
246 1573-7373
247 schema:name Journal of Neuro-Oncology
248 schema:publisher Springer Nature
249 rdf:type schema:Periodical
250 sg:person.01005557013.38 schema:affiliation grid-institutes:grid.411475.2
251 schema:familyName Manganotti
252 schema:givenName Paolo
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005557013.38
254 rdf:type schema:Person
255 sg:person.01031230110.69 schema:affiliation grid-institutes:grid.411475.2
256 schema:familyName Alessandrini
257 schema:givenName Franco
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031230110.69
259 rdf:type schema:Person
260 sg:person.01060645151.72 schema:affiliation grid-institutes:grid.411475.2
261 schema:familyName Sala
262 schema:givenName Francesco
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060645151.72
264 rdf:type schema:Person
265 sg:person.01170414104.74 schema:affiliation grid-institutes:grid.411475.2
266 schema:familyName Tramontano
267 schema:givenName Vincenzo
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170414104.74
269 rdf:type schema:Person
270 sg:person.01261705110.33 schema:affiliation grid-institutes:grid.411475.2
271 schema:familyName Beltramello
272 schema:givenName Alberto
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261705110.33
274 rdf:type schema:Person
275 sg:person.01301530520.96 schema:affiliation grid-institutes:grid.411475.2
276 schema:familyName Gambin
277 schema:givenName Roberta
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301530520.96
279 rdf:type schema:Person
280 sg:person.01330346373.09 schema:affiliation grid-institutes:grid.411475.2
281 schema:familyName Santini
282 schema:givenName Barbara
283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330346373.09
284 rdf:type schema:Person
285 sg:person.013712032777.12 schema:affiliation grid-institutes:grid.5611.3
286 schema:familyName Locatelli
287 schema:givenName Francesca
288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013712032777.12
289 rdf:type schema:Person
290 sg:person.016054451775.59 schema:affiliation grid-institutes:grid.416422.7
291 schema:familyName Lanteri
292 schema:givenName Paola
293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016054451775.59
294 rdf:type schema:Person
295 sg:person.0604742273.27 schema:affiliation grid-institutes:grid.411475.2
296 schema:familyName Talacchi
297 schema:givenName Andrea
298 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604742273.27
299 rdf:type schema:Person
300 sg:person.0612376172.58 schema:affiliation grid-institutes:grid.411475.2
301 schema:familyName Gerosa
302 schema:givenName Massimo
303 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612376172.58
304 rdf:type schema:Person
305 sg:person.0721656754.47 schema:affiliation grid-institutes:grid.411475.2
306 schema:familyName Turazzi
307 schema:givenName Sergio
308 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721656754.47
309 rdf:type schema:Person
310 sg:person.0752175503.53 schema:affiliation grid-institutes:grid.411475.2
311 schema:familyName Ganau
312 schema:givenName Mario
313 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752175503.53
314 rdf:type schema:Person
315 sg:pub.10.1007/978-1-4899-3242-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1109705877
316 https://doi.org/10.1007/978-1-4899-3242-6
317 rdf:type schema:CreativeWork
318 sg:pub.10.1007/bf01541777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027860749
319 https://doi.org/10.1007/bf01541777
320 rdf:type schema:CreativeWork
321 sg:pub.10.1007/s00216-008-2443-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026887725
322 https://doi.org/10.1007/s00216-008-2443-8
323 rdf:type schema:CreativeWork
324 sg:pub.10.1007/s007010070088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027942010
325 https://doi.org/10.1007/s007010070088
326 rdf:type schema:CreativeWork
327 grid-institutes:grid.411475.2 schema:alternateName Division of Neuroradiology, University Hospital, Verona, Italy
328 Division of Neurosurgery, University Hospital, Verona, Italy
329 Section of Neurology, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy
330 Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, P. Stefani 1, 37126, Verona, Italy
331 Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy
332 schema:name Division of Neuroradiology, University Hospital, Verona, Italy
333 Division of Neurosurgery, University Hospital, Verona, Italy
334 Section of Neurology, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy
335 Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, P. Stefani 1, 37126, Verona, Italy
336 Section of Neurosurgery, Department of Neurological Sciences and Vision, University Hospital, Verona, Italy
337 rdf:type schema:Organization
338 grid-institutes:grid.416422.7 schema:alternateName Division of Neurology, “Sacro Cuore” Hospital, Negrar, Verona, Italy
339 schema:name Division of Neurology, “Sacro Cuore” Hospital, Negrar, Verona, Italy
340 rdf:type schema:Organization
341 grid-institutes:grid.5611.3 schema:alternateName Section of Epidemiology and Medical Statistics, Department of Hygiene and Public Health, University of Verona, Verona, Italy
342 schema:name Section of Epidemiology and Medical Statistics, Department of Hygiene and Public Health, University of Verona, Verona, Italy
343 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...