Structural organization of C60 fullerene, doxorubicin, and their complex in physiological solution as promising antitumor agents View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-01-21

AUTHORS

Yu. I. Prylutskyy, M. P. Evstigneev, V. V. Cherepanov, O. A. Kyzyma, L. A. Bulavin, N. A. Davidenko, P. Scharff

ABSTRACT

Specific features of structural self-organization of C60 fullerene (1 nm size range), antitumor antibiotic doxorubicin (Dox) and their complex in physiological solution (0.9 % NaCl) have been investigated by means of atomic-force microscopy, dynamic light scattering, and small-angle X-ray scattering. Significant ordering of the mixed system, C60 + Dox, was observed, suggesting the complexation between these drugs, and giving insight into the mechanism of enhancement of Dox antitumor effect on simultaneous administration with C60 fullerene. More... »

PAGES

45

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11051-015-2867-y

DOI

http://dx.doi.org/10.1007/s11051-015-2867-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038060459


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