Yeast Oropharyngeal Colonization in Human Immunodeficiency Virus-Infected Patients in Central Taiwan View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-05-08

AUTHORS

Mao-Wang Ho, Yun-Liang Yang, Chih-Chao Lin, Chih-Yu Chi, Hui-Ting Chen, Po-Chang Lin, Li-Yun Hsieh, Chia-Hui Chou, Wen-Li Chu, Chiou-Pyng Wu, Tsai-Ling Lauderdale, Hsiu-Jung Lo

ABSTRACT

A prospective, cross-sectional study was conducted at a medical center in central Taiwan to understand the prevalence, associated factors, and microbiologic features for oropharyngeal yeast colonization in human immunodeficiency virus-infected outpatients. Oral yeast colonization was detected in 127 (45 %) patients, including 21 (16.5 %) colonized by more than one species. Of the 154 isolates, Candida albicans was the most common species (114, 74 %), followed by Candida dubliniensis (10, 6.5 %), Candida glabrata (10, 6.5 %), Candida tropicalis (7, 4.5 %), and 13 others. We found that receiving antituberculous drug (p = 0.046) or atazanavir (p = 0.045) was two predictors for patients colonized by non-C. albicans species (p = 0.005) and risking mixed yeast colonization (p = 0.009). Even though our data showed that clinical antifungal drugs remained effective in vitro against the colonizing yeasts, the increased mixed yeast colonization indicates a potential issue for controlling mixed infections in hospital settings. More... »

PAGES

309-317

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11046-014-9753-5

DOI

http://dx.doi.org/10.1007/s11046-014-9753-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000830933

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24804977


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