Ontology type: schema:ScholarlyArticle
2019-02-23
AUTHORSMaxime Sansot, Eugénie Fradin, Rachel Chenouard, Marie Kempf, Achille Kouatchet, Sigismond Lasocki, Carole Lemarié, Matthieu Eveillard, Hélène Pailhoriès
ABSTRACTVentilator-associated pneumonia (VAP) are responsible for an increase in morbidity, mortality, and prolonged hospital stay. A multiplex PCR kit such as the FilmArray® BCID panel could allow early adaptation of antimicrobial therapy, which is crucial for clinical outcomes. The purpose of this study was to test the performances of FilmArray® BCID panel for the detection of bacteria producing VAP. We tested the FilmArray® BCID panel on 50 bronchoalveolar lavages (BALs), from patients hospitalized in two intensive care units at the Angers university hospital, compared to the conventional culture-based method. The sensitivity and the specificity of the FilmArray® BCID panel were 67.2% and 98.9% respectively. They were 88.6% and 98.3% respectively when considering BALs with a positive culture > 104 CFU/mL, and 94.7% and 99.6% respectively if considering BALs with a positive direct examination. This study underlines the good performance of the FilmArray® BCID panel for BAL fluid analysis. In case of positive direct examination, this test allows reliable results that can be obtained at an early stage, facilitating the early adaptation of antimicrobial therapy. More... »
PAGES1-8
http://scigraph.springernature.com/pub.10.1007/s11033-019-04710-0
DOIhttp://dx.doi.org/10.1007/s11033-019-04710-0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1112361026
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30798486
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Sansot",
"givenName": "Maxime",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"R\u00e9animation Chirurgicale A, CHU Angers, Angers, France"
],
"type": "Organization"
},
"familyName": "Fradin",
"givenName": "Eug\u00e9nie",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Chenouard",
"givenName": "Rachel",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Kempf",
"givenName": "Marie",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"R\u00e9animation M\u00e9dicale, CHU Angers, Angers, France"
],
"type": "Organization"
},
"familyName": "Kouatchet",
"givenName": "Achille",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"R\u00e9animation Chirurgicale A, CHU Angers, Angers, France"
],
"type": "Organization"
},
"familyName": "Lasocki",
"givenName": "Sigismond",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Lemari\u00e9",
"givenName": "Carole",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Eveillard",
"givenName": "Matthieu",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Angers",
"id": "https://www.grid.ac/institutes/grid.411147.6",
"name": [
"Laboratoire de Bact\u00e9riologie, CHU Angers, 4 rue Larrey, 49933, Angers cedex, France"
],
"type": "Organization"
},
"familyName": "Pailhori\u00e8s",
"givenName": "H\u00e9l\u00e8ne",
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1086/664049",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002385195"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jac/dkr137",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003214816"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1164/rccm.200405-644st",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008391386"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1183/13993003.01144-2016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010949383"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1183/13993003.01144-2016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010949383"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1183/13993003.01144-2016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010949383"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.diagmicrobio.2014.07.009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011404503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000055380.86458.1e",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012206466"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000055380.86458.1e",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012206466"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1473-3099(13)70081-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019661348"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.diagmicrobio.2015.10.023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022242854"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1378/chest.122.1.262",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024827161"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1378/chest.122.1.262",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024827161"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000181731.53912.d9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029905278"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000181731.53912.d9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029905278"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/cid/civ447",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040449656"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jcrc.2007.08.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041842475"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1086/653062",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053617197"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jcm.00325-14",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053716566"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1099/jmm.0.000180",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060390470"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cmi.2018.06.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1104524094"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-02-23",
"datePublishedReg": "2019-02-23",
"description": "Ventilator-associated pneumonia (VAP) are responsible for an increase in morbidity, mortality, and prolonged hospital stay. A multiplex PCR kit such as the FilmArray\u00ae BCID panel could allow early adaptation of antimicrobial therapy, which is crucial for clinical outcomes. The purpose of this study was to test the performances of FilmArray\u00ae BCID panel for the detection of bacteria producing VAP. We tested the FilmArray\u00ae BCID panel on 50 bronchoalveolar lavages (BALs), from patients hospitalized in two intensive care units at the Angers university hospital, compared to the conventional culture-based method. The sensitivity and the specificity of the FilmArray\u00ae BCID panel were 67.2% and 98.9% respectively. They were 88.6% and 98.3% respectively when considering BALs with a positive culture\u2009>\u2009104\u00a0CFU/mL, and 94.7% and 99.6% respectively if considering BALs with a positive direct examination. This study underlines the good performance of the FilmArray\u00ae BCID panel for BAL fluid analysis. In case of positive direct examination, this test allows reliable results that can be obtained at an early stage, facilitating the early adaptation of antimicrobial therapy.",
"genre": "research_article",
"id": "sg:pub.10.1007/s11033-019-04710-0",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1018503",
"issn": [
"0301-4851",
"1573-4978"
],
"name": "Molecular Biology Reports",
"type": "Periodical"
}
],
"name": "Performance of the extended use of the FilmArray\u00ae BCID panel kit for bronchoalveolar lavage analysis",
"pagination": "1-8",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"6b96a06d5cefcac6701b6a786ff0b9a165458307219ce4e80eb01d2d21b61f86"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30798486"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"0403234"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s11033-019-04710-0"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1112361026"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s11033-019-04710-0",
"https://app.dimensions.ai/details/publication/pub.1112361026"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T09:31",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000346_0000000346/records_99803_00000005.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs11033-019-04710-0"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11033-019-04710-0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11033-019-04710-0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11033-019-04710-0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11033-019-04710-0'
This table displays all metadata directly associated to this object as RDF triples.
160 TRIPLES
21 PREDICATES
42 URIs
18 LITERALS
7 BLANK NODES