The evaluation of the usefulness of pedigree verification-dedicated SNPs for breed assignment in three polish cattle populations View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-09-22

AUTHORS

Artur Gurgul, Dominika Rubiś, Tomasz Ząbek, Kacper Żukowski, Klaudia Pawlina, Ewelina Semik, Monika Bugno-Poniewierska

ABSTRACT

The breed assignment in cattle is one of the issues of molecular genetics which needs further testing and development. Although several statistical approaches have been developed to enable such application, the obtained results strongly depend on specific populations differentiation and power of markers discrimination or their informativeness. Currently, all breeding animals are being tested for parentage with the use of panel of 12 microsatellite markers, which in near future probably will be replaced by about 100 single nucleotide polymorphisms (SNPs). Despite the fact that SNPs are mainly bi-allelic, the multilocus genotypes can reach the level of polymorphism of a panel of microsatellite markers. In this study we attempted to determine the breed of origin of 741 cattle by using 120 SNPs dedicated for parentage testing and included in the BovineSNP50 BeadChip genotyping assay (Illumina). The applied Bayesian and frequency-based methods allowed such differentiation, however, the reliability of the results was not completely satisfying, suggesting that the studied markers are not the best tool for breed assignment. More... »

PAGES

6803-6809

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11033-013-2797-7

DOI

http://dx.doi.org/10.1007/s11033-013-2797-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007492793

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24057257


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