Ontology type: schema:ScholarlyArticle
2018-01
AUTHORSMichele Menotta, Sara Biagiotti, Sara Orazi, Luigia Rossi, Luciana Chessa, Vincenzo Leuzzi, Daniela D’Agnano, Alessandro Plebani, Annarosa Soresina, Mauro Magnani
ABSTRACTAtaxia telangiectasia (AT) is a rare incurable genetic disease caused by biallelic mutations in the Ataxia telangiectasia-mutated gene. Intra-erythrocyte infusion of dexamethasone improves clinical outcomes in AT patients; however, the molecular mechanisms that lead to this improvement remain unknown. Hence, to gain a better understanding of these mechanisms, we assessed the effects of glucocorticoid administration on gene expression in the blood of AT patients. Whole blood was obtained from nine children enrolled in a phase two clinical trial, who were being treated with dexamethasone (AT Dexa), from six untreated AT patients (AT) and from six healthy volunteers (WT). CodeLink Whole Genome Bioarrays were used to assess transcript expression. The reliability of the differentially expressed genes (DEGs) was verified by qRT-PCR analysis. The enriched Gene Ontology (GO) terms and the pathways of the Kyoto Encyclopedia of Genes and Genomes (KEGG) of DEGs obtained by group comparisons were achieved using the Database for Annotation, Visualization and Integrated Discovery (DAVID). Functional network analyses were computed by Reactome FI. The likely involved transcription factors were revealed by iRegulon. Among the identified DEGs influenced by the pathology and restored by dexamethasone, we detected 522 upregulated probes coding for known proteins, while 22 probes were downregulated, as they were in healthy subjects. These results provide useful information and represent a first step towards gaining a better understanding of the underlying mechanisms of the effects of dexamethasone on AT patients. More... »
PAGES153-166
http://scigraph.springernature.com/pub.10.1007/s11010-017-3122-x
DOIhttp://dx.doi.org/10.1007/s11010-017-3122-x
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1090892512
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28744812
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Genetics",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adolescent",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ataxia Telangiectasia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Child",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Dexamethasone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Expression Regulation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Real-Time Polymerase Chain Reaction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Reverse Transcriptase Polymerase Chain Reaction",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Urbino",
"id": "https://www.grid.ac/institutes/grid.12711.34",
"name": [
"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d, Via Saffi 2, 61029, Urbino, PU, Italy"
],
"type": "Organization"
},
"familyName": "Menotta",
"givenName": "Michele",
"id": "sg:person.01125765675.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125765675.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Urbino",
"id": "https://www.grid.ac/institutes/grid.12711.34",
"name": [
"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d, Via Saffi 2, 61029, Urbino, PU, Italy"
],
"type": "Organization"
},
"familyName": "Biagiotti",
"givenName": "Sara",
"id": "sg:person.01104077372.38",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104077372.38"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Urbino",
"id": "https://www.grid.ac/institutes/grid.12711.34",
"name": [
"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d, Via Saffi 2, 61029, Urbino, PU, Italy"
],
"type": "Organization"
},
"familyName": "Orazi",
"givenName": "Sara",
"id": "sg:person.012366056221.12",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012366056221.12"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Urbino",
"id": "https://www.grid.ac/institutes/grid.12711.34",
"name": [
"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d, Via Saffi 2, 61029, Urbino, PU, Italy"
],
"type": "Organization"
},
"familyName": "Rossi",
"givenName": "Luigia",
"id": "sg:person.012733041772.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012733041772.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Sapienza University of Rome",
"id": "https://www.grid.ac/institutes/grid.7841.a",
"name": [
"Department of Clinical and Molecular Medicine, Sapienza Universit\u00e0 di Roma, Rome, Italy"
],
"type": "Organization"
},
"familyName": "Chessa",
"givenName": "Luciana",
"id": "sg:person.01210613030.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210613030.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Sapienza University of Rome",
"id": "https://www.grid.ac/institutes/grid.7841.a",
"name": [
"Department of Pediatrics and Child Neurology and Psychiatry, Sapienza Universit\u00e0 di Roma, Rome, Italy"
],
"type": "Organization"
},
"familyName": "Leuzzi",
"givenName": "Vincenzo",
"id": "sg:person.0612121222.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612121222.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Sapienza University of Rome",
"id": "https://www.grid.ac/institutes/grid.7841.a",
"name": [
"Department of Pediatrics and Child Neurology and Psychiatry, Sapienza Universit\u00e0 di Roma, Rome, Italy"
],
"type": "Organization"
},
"familyName": "D\u2019Agnano",
"givenName": "Daniela",
"id": "sg:person.0774463022.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774463022.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Brescia",
"id": "https://www.grid.ac/institutes/grid.7637.5",
"name": [
"Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute of Molecular Medicine \u201cA. Nocivelli\u201d, Spedali Civili and University of Brescia, Brescia, Italy"
],
"type": "Organization"
},
"familyName": "Plebani",
"givenName": "Alessandro",
"id": "sg:person.01111477410.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111477410.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Brescia",
"id": "https://www.grid.ac/institutes/grid.7637.5",
"name": [
"Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute of Molecular Medicine \u201cA. Nocivelli\u201d, Spedali Civili and University of Brescia, Brescia, Italy"
],
"type": "Organization"
},
"familyName": "Soresina",
"givenName": "Annarosa",
"id": "sg:person.01021536037.33",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021536037.33"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Urbino",
"id": "https://www.grid.ac/institutes/grid.12711.34",
"name": [
"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d, Via Saffi 2, 61029, Urbino, PU, Italy"
],
"type": "Organization"
},
"familyName": "Magnani",
"givenName": "Mauro",
"id": "sg:person.0752252542.98",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752252542.98"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1021/pr101243j",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000282559"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0016422",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000651988"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-10-3397",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000697854"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/febs.13901",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001601870"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bcmd.2004.04.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002331703"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1468-1331.2010.03203.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002417286"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1182/blood-2011-08-373639",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003618767"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00003246-200204000-00034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004498367"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00003246-200204000-00034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004498367"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cellsig.2015.05.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006815324"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cellsig.2015.05.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006815324"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0013984",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006850384"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1468-1331.2009.02600.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007007344"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1468-1331.2009.02600.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007007344"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mds.25126",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009326820"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrm2514",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009446789",
"https://doi.org/10.1038/nrm2514"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/ba20000087",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009504998"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/gb-2010-11-5-r53",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012013843",
"https://doi.org/10.1186/gb-2010-11-5-r53"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m112.344473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012734720"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.01432-14",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013309104"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.dnarep.2004.04.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014179993"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11010-014-2013-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014279229",
"https://doi.org/10.1007/s11010-014-2013-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000350120",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015553335"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/nxi.0000000000000098",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018265729"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/nxi.0000000000000098",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018265729"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m112.403832",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019501261"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/carcin/bgt128",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022840339"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.dnarep.2008.03.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024177760"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0167-4781(99)00197-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024775115"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/npp.2011.331",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025526313",
"https://doi.org/10.1038/npp.2011.331"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2014.02.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026680310"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0076-6879(06)11009-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027510687"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.dnarep.2004.04.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028251797"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pcbi.1003731",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031364157"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1468-1331.2008.02060.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033349556"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-12-3453",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034929549"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1111/j.1572-0241.2008.02103.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035274192",
"https://doi.org/10.1111/j.1572-0241.2008.02103.x"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.dnarep.2013.11.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035400606"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1750-1172-9-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036998157",
"https://doi.org/10.1186/1750-1172-9-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.5114/aoms.2012.31623",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039297941"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/onc.2012.138",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039672501",
"https://doi.org/10.1038/onc.2012.138"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpcell.00309.2009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040032441"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s12013-016-0775-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040204206",
"https://doi.org/10.1007/s12013-016-0775-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s12013-016-0775-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040204206",
"https://doi.org/10.1007/s12013-016-0775-0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mib.0b013e3182874065",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041331985"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mib.0b013e3182874065",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041331985"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/jcs.073924",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042921145"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archneur.63.10.1479",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044242012"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj2530401",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047007611"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj2530401",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047007611"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000345995",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047990390"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1086/301755",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058609362"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1086/342974",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058639608"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/15230860260196254",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059212295"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1667/rr3198.1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068196270"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2144/03342mt01",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1075245738"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082794095",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpcell.1997.272.1.c184",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083048366"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-01",
"datePublishedReg": "2018-01-01",
"description": "Ataxia telangiectasia (AT) is a rare incurable genetic disease caused by biallelic mutations in the Ataxia telangiectasia-mutated gene. Intra-erythrocyte infusion of dexamethasone improves clinical outcomes in AT patients; however, the molecular mechanisms that lead to this improvement remain unknown. Hence, to gain a better understanding of these mechanisms, we assessed the effects of glucocorticoid administration on gene expression in the blood of AT patients. Whole blood was obtained from nine children enrolled in a phase two clinical trial, who were being treated with dexamethasone (AT Dexa), from six untreated AT patients (AT) and from six healthy volunteers (WT). CodeLink Whole Genome Bioarrays were used to assess transcript expression. The reliability of the differentially expressed genes (DEGs) was verified by qRT-PCR analysis. The enriched Gene Ontology (GO) terms and the pathways of the Kyoto Encyclopedia of Genes and Genomes (KEGG) of DEGs obtained by group comparisons were achieved using the Database for Annotation, Visualization and Integrated Discovery (DAVID). Functional network analyses were computed by Reactome FI. The likely involved transcription factors were revealed by iRegulon. Among the identified DEGs influenced by the pathology and restored by dexamethasone, we detected 522 upregulated probes coding for known proteins, while 22 probes were downregulated, as they were in healthy subjects. These results provide useful information and represent a first step towards gaining a better understanding of the underlying mechanisms of the effects of dexamethasone on AT patients.",
"genre": "research_article",
"id": "sg:pub.10.1007/s11010-017-3122-x",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1016672",
"issn": [
"0300-8177",
"1573-4919"
],
"name": "Molecular and Cellular Biochemistry",
"type": "Periodical"
},
{
"issueNumber": "1-2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "438"
}
],
"name": "In vivo effects of dexamethasone on blood gene expression in ataxia telangiectasia",
"pagination": "153-166",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"74e56035b4d0ad1380a63110b6fc1c06d10cb070e4118c5287dd6aa9f9b4d058"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28744812"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"0364456"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s11010-017-3122-x"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1090892512"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s11010-017-3122-x",
"https://app.dimensions.ai/details/publication/pub.1090892512"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:04",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89826_00000003.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs11010-017-3122-x"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11010-017-3122-x'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11010-017-3122-x'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11010-017-3122-x'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11010-017-3122-x'
This table displays all metadata directly associated to this object as RDF triples.
339 TRIPLES
21 PREDICATES
90 URIs
31 LITERALS
19 BLANK NODES