Water structure and elastin-like peptide aggregation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-04

AUTHORS

Jany Dandurand, Valérie Samouillan, Colette Lacabanne, Antonietta Pepe, Brigida Bochicchio

ABSTRACT

For the first time, calorimetric studies performed at very low temperature highlighted the preliminary and required conditions for further aggregation/coacervation of peptides from elastin in solution through the structural water reorganization around the peptides. For this purpose, we firstly characterized by turbidimetry and differential scanning calorimetry the synthetic S4 fragment peptide containing the XGGZG motif (where X and Z correspond to Valine or Leucine) which is able to form amyloid fibres under certain conditions. We also investigated two medium-sized elastin-related model elastin peptides containing the VGVPG motif (E50 and E18) as well as their analogues where proline is hydroxylated in hydroxyproline. These peptides were shown to coacervate, and a close correlation was found between the inverse transition temperature obtained by turbidimetry and the clathrate-like structures evidenced at low temperature by the calorimetric method. More... »

PAGES

419-426

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10973-014-4254-9

DOI

http://dx.doi.org/10.1007/s10973-014-4254-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005718986


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10973-014-4254-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10973-014-4254-9'

Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10973-014-4254-9'


 

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