Physicochemical Characterization and In Vitro Cytotoxic Effect of 3-Hydroxyflavone in a Silver Nanoparticles Complex View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-07-24

AUTHORS

Mariana Voicescu, Oana Craciunescu, Lucia Moldovan, Mihai Anastasescu, Daniel G. Angelescu, Valentin S. Teodorescu

ABSTRACT

The aim of this work was to characterize the physico-chemical properties of 3-hydroxyflavone (3-HF) in a silver nanoparticles complex (SNPs) using UV–vis and Fluorescence spectroscopy, Atomic Force Microscopy (AFM) and Transmission Electron Microscopy (TEM) analysis. One also evaluated its effect on the cell viability and morphology of L929 mouse fibroblast cells in vitro. The contribution of the carrier protein, Bovine Serum Albumin (BSA) to 3-HF properties has also been investigated. 3-HF in BSA/SNPs systems presented no cytotoxic effect in L929 mouse fibroblast cells at any of the tested concentrations. The results are discussed with relevance to the oxidative stress process. More... »

PAGES

1215-1223

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10895-015-1608-z

DOI

http://dx.doi.org/10.1007/s10895-015-1608-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017740735

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26204812


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