Ontology type: schema:ScholarlyArticle
2017-08
AUTHORSÁngel Matute-Llorente, Alejandro González-Agüero, Luis A. Moreno-Aznar, Germán Vicente-Rodríguez, José A. Casajús
ABSTRACTVitamin D (vitD) deficiency is a worldwide problem. Therefore, the main aims of this study were to compare 25-hydroxivitamin D levels (25(OH)D) in adolescents with and without Down syndrome (DS) and to study the relationship between 25(OH)D and bone. Eleven adolescents with DS (6 females) aged 15.5 ± 2.8 years and sixteen healthy controls (non-DS) (6 females) aged 14.3 ± 2.2 years were evaluated by bone imaging techniques. Blood samples were collected to determine vitD levels. Independent t-tests and analyses of covariance controlling for age, height, sex, sexual maturation, calcium intake and body mass index were performed to evaluate differences in 25(OH)D levels between groups. Pearson’s correlation test and multiple linear regression analyses were performed to examine the association between 25(OH)D and bone mass. Adolescents with DS had lower 25(OH)D (22.8 ± 8.0 vs. 36.0 ± 6.5 ng/ml) than non-DS (d = 1.81; p < 0.05). Only 18% of participants with DS reached the recommended level of 30 ng/ml of 25(OH)D. No significant group interactions were found for any bone variable (all p > 0.05) but linear regression analyses suggested that 25(OH)D influenced positively femoral neck bone mineral density (β = 0.477, p = 0.038) and content at the 4% of the length of the tibia (β = 0.453, p = 0.008) in the non-DS and cortical volumetric bone mineral density at the 38% (β = 0.841, p = 0.034) in the DS. Adolescents with DS had lower levels of 25(OH)D and higher prevalence of vitD deficiency compared with non-DS. Associations between 25(OH)D and bone parameters were not observed for adolescents with DS but medium and positive correlations were observed in the non-DS group. More... »
PAGES611-624
http://scigraph.springernature.com/pub.10.1007/s10882-017-9545-1
DOIhttp://dx.doi.org/10.1007/s10882-017-9545-1
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1084760264
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Zaragoza",
"id": "https://www.grid.ac/institutes/grid.11205.37",
"name": [
"GENUD (Growth, Exercise, NUtrition and Development) Research Group, Universidad de Zaragoza, C/ Pedro Cerbuna, 12 50009, Zaragoza, Spain",
"(FCSD) Faculty of Health and Sport Sciences, Department of Physiatry and Nursing, University of Zaragoza, Ronda Misericordia 5, 22001, Huesca, Spain",
"Departamento de Fisiatr\u00eda y Enfermer\u00eda, Facultad de Ciencias de la Salud y del Deporte, Instituto Agroalimentario de Arag\u00f3n-IA2-(Universidad de Zaragoza-CITA), C/ Pedro Cerbuna 12, Grupo GENUD, 50009, Zaragoza, Spain"
],
"type": "Organization"
},
"familyName": "Matute-Llorente",
"givenName": "\u00c1ngel",
"id": "sg:person.0661777276.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661777276.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zaragoza",
"id": "https://www.grid.ac/institutes/grid.11205.37",
"name": [
"GENUD (Growth, Exercise, NUtrition and Development) Research Group, Universidad de Zaragoza, C/ Pedro Cerbuna, 12 50009, Zaragoza, Spain",
"(FCSD) Faculty of Health and Sport Sciences, Department of Physiatry and Nursing, University of Zaragoza, Ronda Misericordia 5, 22001, Huesca, Spain",
"Departamento de Fisiatr\u00eda y Enfermer\u00eda, Facultad de Ciencias de la Salud y del Deporte, Instituto Agroalimentario de Arag\u00f3n-IA2-(Universidad de Zaragoza-CITA), C/ Pedro Cerbuna 12, Grupo GENUD, 50009, Zaragoza, Spain"
],
"type": "Organization"
},
"familyName": "Gonz\u00e1lez-Ag\u00fcero",
"givenName": "Alejandro",
"id": "sg:person.01124337330.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124337330.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition",
"id": "https://www.grid.ac/institutes/grid.484042.e",
"name": [
"GENUD (Growth, Exercise, NUtrition and Development) Research Group, Universidad de Zaragoza, C/ Pedro Cerbuna, 12 50009, Zaragoza, Spain",
"Departamento de Fisiatr\u00eda y Enfermer\u00eda, Facultad de Ciencias de la Salud y del Deporte, Instituto Agroalimentario de Arag\u00f3n-IA2-(Universidad de Zaragoza-CITA), C/ Pedro Cerbuna 12, Grupo GENUD, 50009, Zaragoza, Spain",
"Instituto de Investigaci\u00f3n Sanitaria Arag\u00f3n (IIS Arag\u00f3n), Zaragoza, Spain",
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n (CIBERObn), Madrid, Spain"
],
"type": "Organization"
},
"familyName": "Moreno-Aznar",
"givenName": "Luis A.",
"id": "sg:person.015223063344.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015223063344.50"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zaragoza",
"id": "https://www.grid.ac/institutes/grid.11205.37",
"name": [
"GENUD (Growth, Exercise, NUtrition and Development) Research Group, Universidad de Zaragoza, C/ Pedro Cerbuna, 12 50009, Zaragoza, Spain",
"(FCSD) Faculty of Health and Sport Sciences, Department of Physiatry and Nursing, University of Zaragoza, Ronda Misericordia 5, 22001, Huesca, Spain",
"Departamento de Fisiatr\u00eda y Enfermer\u00eda, Facultad de Ciencias de la Salud y del Deporte, Instituto Agroalimentario de Arag\u00f3n-IA2-(Universidad de Zaragoza-CITA), C/ Pedro Cerbuna 12, Grupo GENUD, 50009, Zaragoza, Spain"
],
"type": "Organization"
},
"familyName": "Vicente-Rodr\u00edguez",
"givenName": "Germ\u00e1n",
"id": "sg:person.01313667237.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313667237.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zaragoza",
"id": "https://www.grid.ac/institutes/grid.11205.37",
"name": [
"GENUD (Growth, Exercise, NUtrition and Development) Research Group, Universidad de Zaragoza, C/ Pedro Cerbuna, 12 50009, Zaragoza, Spain",
"(FCSD) Faculty of Health and Sport Sciences, Department of Physiatry and Nursing, University of Zaragoza, Ronda Misericordia 5, 22001, Huesca, Spain",
"Departamento de Fisiatr\u00eda y Enfermer\u00eda, Facultad de Ciencias de la Salud y del Deporte, Instituto Agroalimentario de Arag\u00f3n-IA2-(Universidad de Zaragoza-CITA), C/ Pedro Cerbuna 12, Grupo GENUD, 50009, Zaragoza, Spain"
],
"type": "Organization"
},
"familyName": "Casaj\u00fas",
"givenName": "Jos\u00e9 A.",
"id": "sg:person.0776225676.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776225676.99"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1359/jbmr.1997.12.10.1547",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000447576"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.ejcn.1602357",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000759687",
"https://doi.org/10.1038/sj.ejcn.1602357"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.ejcn.1602357",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000759687",
"https://doi.org/10.1038/sj.ejcn.1602357"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/000992289703600409",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002957430"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/000992289703600409",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002957430"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jocd.2007.12.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003823854"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jpeds.2012.12.087",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004221600"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1352/1934-9556-50.2.109",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004349380"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-011-1884-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006820942",
"https://doi.org/10.1007/s00198-011-1884-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.ejcn.1602959",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006834200",
"https://doi.org/10.1038/sj.ejcn.1602959"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s12020-008-9115-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013095106",
"https://doi.org/10.1007/s12020-008-9115-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2015/896758",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014254881"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s002230010035",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014861983",
"https://doi.org/10.1007/s002230010035"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/adc.51.3.170",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016682307"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ejim.2015.05.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020475027"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmra070553",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023249044"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2788.2007.00992.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026715703"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bone.2003.08.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027509502"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm199803193381201",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028139032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0301-2115(01)00478-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029855786"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2011-0385",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029888078"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s003300050726",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030602696",
"https://doi.org/10.1007/s003300050726"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/pgmj.2006.052787",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030945423"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/pgmj.2006.052787",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030945423"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2013.281053",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031488893"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-015-3232-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032919685",
"https://doi.org/10.1007/s00198-015-3232-9"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2788.2009.01218.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033208503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2788.2009.01218.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033208503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0007114511003527",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033390288"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-010-1443-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034506824",
"https://doi.org/10.1007/s00198-010-1443-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bone.2010.09.025",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035119656"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2788.1992.tb00512.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038065443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2788.1992.tb00512.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038065443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.beem.2011.05.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038590162"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1472-6823-13-22",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041546670",
"https://doi.org/10.1186/1472-6823-13-22"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0002-9343(99)00460-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042354316"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-012-2041-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042749935",
"https://doi.org/10.1007/s00198-012-2041-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/07315724.2003.10719287",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043273084"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0838.2009.01016.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044054309"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrendo.2009.80",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044157131",
"https://doi.org/10.1038/nrendo.2009.80"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1352/0895-8017(1998)103<0019:pwmrha>2.0.co;2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045021400"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-004-1687-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046740568",
"https://doi.org/10.1007/s00198-004-1687-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3945/ajcn.115.120873",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052796874"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1759720x15588521",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064077582"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1759720x15588521",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064077582"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2008-0784",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064290689"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2011-2601",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064293170"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jcem-73-6-1332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064317013"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075178963",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077311715",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3305/nh.2013.28.4.6509",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078762032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3305/nh.2014.30.1.7539",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078958010"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3305/nh.2014.30.2.7603",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078970692"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082845345",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/126.suppl_4.1159s",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082890568"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-08",
"datePublishedReg": "2017-08-01",
"description": "Vitamin D (vitD) deficiency is a worldwide problem. Therefore, the main aims of this study were to compare 25-hydroxivitamin D levels (25(OH)D) in adolescents with and without Down syndrome (DS) and to study the relationship between 25(OH)D and bone. Eleven adolescents with DS (6 females) aged 15.5 \u00b1 2.8 years and sixteen healthy controls (non-DS) (6 females) aged 14.3 \u00b1 2.2 years were evaluated by bone imaging techniques. Blood samples were collected to determine vitD levels. Independent t-tests and analyses of covariance controlling for age, height, sex, sexual maturation, calcium intake and body mass index were performed to evaluate differences in 25(OH)D levels between groups. Pearson\u2019s correlation test and multiple linear regression analyses were performed to examine the association between 25(OH)D and bone mass. Adolescents with DS had lower 25(OH)D (22.8 \u00b1 8.0 vs. 36.0 \u00b1 6.5 ng/ml) than non-DS (d = 1.81; p < 0.05). Only 18% of participants with DS reached the recommended level of 30 ng/ml of 25(OH)D. No significant group interactions were found for any bone variable (all p > 0.05) but linear regression analyses suggested that 25(OH)D influenced positively femoral neck bone mineral density (\u03b2 = 0.477, p = 0.038) and content at the 4% of the length of the tibia (\u03b2 = 0.453, p = 0.008) in the non-DS and cortical volumetric bone mineral density at the 38% (\u03b2 = 0.841, p = 0.034) in the DS. Adolescents with DS had lower levels of 25(OH)D and higher prevalence of vitD deficiency compared with non-DS. Associations between 25(OH)D and bone parameters were not observed for adolescents with DS but medium and positive correlations were observed in the non-DS group.",
"genre": "research_article",
"id": "sg:pub.10.1007/s10882-017-9545-1",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1101758",
"issn": [
"1056-263X",
"1573-3580"
],
"name": "Journal of Developmental and Physical Disabilities",
"type": "Periodical"
},
{
"issueNumber": "4",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "29"
}
],
"name": "Relationship between Vitamin D Levels and Bone Tissue in Adolescents with and without Down Syndrome",
"pagination": "611-624",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"8f8288fd68518549841d9ac9f1e8ac9a9b55336e01f210dca33ee1976ada6672"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10882-017-9545-1"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1084760264"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10882-017-9545-1",
"https://app.dimensions.ai/details/publication/pub.1084760264"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:38",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113677_00000004.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs10882-017-9545-1"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10882-017-9545-1'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10882-017-9545-1'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10882-017-9545-1'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10882-017-9545-1'
This table displays all metadata directly associated to this object as RDF triples.
253 TRIPLES
21 PREDICATES
76 URIs
19 LITERALS
7 BLANK NODES