α′H-Dicalcium silicate bone cement doped with tricalcium phosphate: characterization, bioactivity and biocompatibility View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-02

AUTHORS

Piedad N. de Aza, Fausto Zuleta, Pablo Velasquez, Nestor Vicente-Salar, Juan A. Reig

ABSTRACT

The influence of phosphorus doping on the properties of (α'(H))-dicalcium silicate (C(2)S) bone cement was analyzed, in addition to bioactivity and biocompatibility. All the cements were composed of a solid solution of TCP in C(2)S ([Formula: see text]-C(2)S(ss)) as the only phase present. The compressive strength ranged from 3.8-16.3 MPa. Final setting times ranged from 10 to 50 min and were lower for cements with lower L/P content. Calcium silicate hydrate was the principal phase formed during the hydration process of the cements. The cement exhibited a moderate degradation and could induce carbonated hydroxyapatite formation on its surface and into the pores. The cell attachment test showed that the (α'(H))-C(2)SiO(4) solid solution supported human adipose stem cells adhesion and spreading, and the cells established close contacts with the cement after 24 h of culture. The novel (α'(H))-C(2)S(ss) cements might be suitable for potential applications in the biomedical field, preferentially as materials for bone/dental repair. More... »

PAGES

445-452

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10856-013-5084-1

DOI

http://dx.doi.org/10.1007/s10856-013-5084-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043083602

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24218299


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