Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-03

AUTHORS

J. Kronek, J. Lustoň, Z. Kroneková, E. Paulovičová, P. Farkaš, N. Petrenčíková, L. Paulovičová, I. Janigová

ABSTRACT

Novel amphiphilic copolymers on the basis of 2-oxazolines containing a free amino group were prepared. The copolymers were synthesized by the living cationic polymerization of 2-ethyl-2-oxazoline (ETOX) and 2-(4-aminophenyl)-2-oxazoline (APOX). The main goal of this work was the synthesis of water soluble polymer material with the defined number of functional groups necessary for the attachment of proteins and polysaccharides. A high concentration of free amino groups allows immobilization of various biosubstances, e.g. drugs, proteins or polysaccharides. Thermal properties have been studied with respect to the composition of the copolymers. Cytotoxicity and the bioimmunological efficiency of the selected copolymer were studied. More... »

PAGES

879-886

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10856-009-3949-0

DOI

http://dx.doi.org/10.1007/s10856-009-3949-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017633527

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19957102


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