Ontology type: schema:ScholarlyArticle
2012-12
AUTHORSPietro Turco, Antonio D’Onofrio, Giuseppe Stabile, Francesco Solimene, Vincenzo La Rocca, Filippo Vecchione, Assunta Iuliano, Natale Marrazzo, Stefano De Vivo, Ciro Cavallaro, Valter Bianchi, Alessia Agresta, Carmine Ciardiello, Antonio De Simone
ABSTRACTPURPOSE: Patients with permanent atrial fibrillation (AF) who undergo cardiac resynchronization therapy (CRT) may spontaneously recover sinus rhythm during follow-up. We tested the feasibility and efficacy of electrical cardioversion attempted after 3 months of CRT in patients with permanent AF and measured the long-term maintenance of sinus rhythm. METHODS: Twenty-eight consecutive patients with permanent AF in whom CRT defibrillators had been implanted were scheduled for internal electrical cardioversion after 3 months (group A) and were compared with a control group of 27 patients (group B). RESULTS: In group A, 22 patients (79 %) were eligible for cardioversion; sinus rhythm was restored in 18 (82 %) of these, with no procedural complications. After 12 months, 16 patients (58 %) in group A were in sinus rhythm, compared with one group B patient who spontaneously recovered sinus rhythm (4 %, p < 0.001). On 12-month evaluation, ejection fraction had improved in both groups, but a reduction in left ventricular end-systolic volume was recorded only in group A patients (p = 0.018 versus baseline). CONCLUSIONS: In patients with permanent AF, the rhythm control strategy consisting of internal cardioversion, performed by means of the implanted cardioverter-defibrillator after 3 months of CRT, was associated with a high rate of sinus rhythm resumption on long-term follow-up and with a better echocardiographic response to CRT than that seen in patients treated according to a rate control strategy. More... »
PAGES331-336
http://scigraph.springernature.com/pub.10.1007/s10840-012-9713-2
DOIhttp://dx.doi.org/10.1007/s10840-012-9713-2
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/22890483
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