The role of angiogenic markers in adverse perinatal outcomes: fresh versus frozen embryo transfers View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12

AUTHORS

Irene Woo, Yen Chan, Intira Sriprasert, Kristin Louie, Sue Ingles, Frank Stanczyk, Lynda K. McGinnis, Karine Chung

ABSTRACT

PURPOSE: We aimed to investigate the angiogenic balance in fresh compared to frozen embryo transfers, and among neonates with adverse perinatal outcomes. METHODS: This was a retrospective cohort study. All IVF cycles resulting in a singleton live birth at a university academic fertility center from January 1, 2011, to December 31, 2013, were examined. Concentrations of sFLT-1 and PlGF were measured in previously frozen serum specimens collected during early gestation at approximately 5 weeks gestation. Patients completed an electronic survey to detail perinatal outcome. RESULTS: We identified 152 singleton live births (103 fresh, 49 frozen). Demographic characteristics were similar between the two groups. Ratios of sFlt-1:PlGF were not different between fresh and frozen transfers. Neonates from fresh cycles had a mean birth weight 202 g lighter (p = 0.01) than frozen cycles, after adjusting for gestational age. Among babies born with poor perinatal outcomes, there was a difference in sFlt-1:PlGF ratios after adjusting for race. In non-Asians, infants born small for gestational age (SGA) (< 10th percentile) had significantly higher sFLT-1:PLGF ratio, median ratio (0.21 vs 0.12, p = 0.016). CONCLUSIONS: Fresh transfers were associated with lower birth weight infants compared to frozen transfers. While there was no difference in sFlt-1:PlGF ratios between fresh and frozen transfers, these ratios were significantly lower in SGA infants, suggesting an imbalance in angiogenic markers during placentation. More... »

PAGES

1639-1643

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10815-017-1023-2

DOI

http://dx.doi.org/10.1007/s10815-017-1023-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091477592

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28871422


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Birth Weight", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cryopreservation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryo Transfer", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fertilization in Vitro", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gestational Age", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Small for Gestational Age", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infertility, Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Live Birth", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Placenta Growth Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vascular Endothelial Growth Factor Receptor-1", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA", 
            "Department of Obstetrics and Gynecology, LAC+USC Medical Center, University of Southern California, 2020 Zonal Avenue IRD 534, 90033, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Woo", 
        "givenName": "Irene", 
        "id": "sg:person.014730475623.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014730475623.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine Keck School of Medicine, University of Southern California, 2020 Zonal Avenue, 90033, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chan", 
        "givenName": "Yen", 
        "id": "sg:person.012357041465.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357041465.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiang Mai University", 
          "id": "https://www.grid.ac/institutes/grid.7132.7", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA", 
            "Department of Obstetrics and Gynecology, Division of Reproductive Health, Chiang Mai University, Chiang Mai, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sriprasert", 
        "givenName": "Intira", 
        "id": "sg:person.01176632731.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176632731.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Louie", 
        "givenName": "Kristin", 
        "id": "sg:person.015526056223.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015526056223.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ingles", 
        "givenName": "Sue", 
        "id": "sg:person.01202315245.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202315245.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stanczyk", 
        "givenName": "Frank", 
        "id": "sg:person.012357675257.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357675257.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McGinnis", 
        "givenName": "Lynda K.", 
        "id": "sg:person.0772600660.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772600660.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chung", 
        "givenName": "Karine", 
        "id": "sg:person.0751376776.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751376776.62"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/humupd/dmu027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000651051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/14767058.2016.1182483", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009513747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2011.05.050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010312058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10815-010-9412-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013989144", 
          "https://doi.org/10.1007/s10815-010-9412-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2012.09.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019816336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.291.6503.1160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020123502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/14767058.2010.531309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020676192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2012.03.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025122818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/beog.2000.0139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025316321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2004.12.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026906532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2004.12.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026906532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2013.08.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028350026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajog.2015.03.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031420103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1746-1596-5-24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033212764", 
          "https://doi.org/10.1186/1746-1596-5-24"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fertnstert.2009.05.091", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034468036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10641955.2014.951490", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034845366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/det272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035616166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0412.2012.01516.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036175429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.placenta.2011.11.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036945134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/14767058.2015.1048431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039668860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.placenta.2003.10.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045983034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/der394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046247627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/uog.13246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047111611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajog.2009.10.891", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047514461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10815-014-0391-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048196357", 
          "https://doi.org/10.1007/s10815-014-0391-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/en.2004-1028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064247035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5468/ogs.2017.60.2.154", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084470111"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-12", 
    "datePublishedReg": "2017-12-01", 
    "description": "PURPOSE: We aimed to investigate the angiogenic balance in fresh compared to frozen embryo transfers, and among neonates with adverse perinatal outcomes.\nMETHODS: This was a retrospective cohort study. All IVF cycles resulting in a singleton live birth at a university academic fertility center from January 1, 2011, to December 31, 2013, were examined. Concentrations of sFLT-1 and PlGF were measured in previously frozen serum specimens collected during early gestation at approximately 5\u00a0weeks gestation. Patients completed an electronic survey to detail perinatal outcome.\nRESULTS: We identified 152 singleton live births (103 fresh, 49 frozen). Demographic characteristics were similar between the two groups. Ratios of sFlt-1:PlGF were not different between fresh and frozen transfers. Neonates from fresh cycles had a mean birth weight 202\u00a0g lighter (p\u00a0=\u00a00.01) than frozen cycles, after adjusting for gestational age. Among babies born with poor perinatal outcomes, there was a difference in sFlt-1:PlGF ratios after adjusting for race. In non-Asians, infants born small for gestational age (SGA) (<\u00a010th percentile) had significantly higher sFLT-1:PLGF ratio, median ratio (0.21 vs 0.12, p\u00a0=\u00a00.016).\nCONCLUSIONS: Fresh transfers were associated with lower birth weight infants compared to frozen transfers. While there was no difference in sFlt-1:PlGF ratios between fresh and frozen transfers, these ratios were significantly lower in SGA infants, suggesting an imbalance in angiogenic markers during placentation.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10815-017-1023-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1095018", 
        "issn": [
          "1058-0468", 
          "1573-7330"
        ], 
        "name": "Journal of Assisted Reproduction and Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "12", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "name": "The role of angiogenic markers in adverse perinatal outcomes: fresh versus frozen embryo transfers", 
    "pagination": "1639-1643", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d12749a614d9cf590cf20303e685b300aecefa8a9d99bf466dc416ab461d6776"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28871422"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9206495"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10815-017-1023-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091477592"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10815-017-1023-2", 
      "https://app.dimensions.ai/details/publication/pub.1091477592"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000517.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s10815-017-1023-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10815-017-1023-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10815-017-1023-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10815-017-1023-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10815-017-1023-2'


 

This table displays all metadata directly associated to this object as RDF triples.

273 TRIPLES      21 PREDICATES      72 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10815-017-1023-2 schema:about N10cf29abe0cd4a21a71711bf4025606c
2 N3c1ded02cfbc4c57afebb0686e373038
3 N405333f37bf64fb69ae469e4dd23c38a
4 N4c2d1826a11c43d4834ec74f549790af
5 N4fb3fdc9ae12479cbeac69ee3a80cfba
6 N55c8549addc4433e8318d5ef0e174f64
7 N60e74bc8f8e545c4acc718be6e065bdd
8 N9341c0e0bd724c2c909bf90d88ab92e9
9 N95ed5793e34d471785a5f1a91e3b3055
10 Na506a4a8db2048ceadf35184901c684b
11 Nb289198217714deb8735d4653dd2f878
12 Ncc2bb6e2ad604a77aa8862d6587a3c6e
13 Nd3c2df9430ba4a60bfad35a6cc92671d
14 Nd9308958cab740858dbf6417adff70b0
15 Ne219137300f24f7caeaa325284bbe04c
16 Nebc1c02c298345069b1b7f712397a6e2
17 Ned62aff0b3ea463c9480746813009c9f
18 anzsrc-for:11
19 anzsrc-for:1114
20 schema:author Nfccab9a1f0374c6ca1213ba2e502bd50
21 schema:citation sg:pub.10.1007/s10815-010-9412-9
22 sg:pub.10.1007/s10815-014-0391-0
23 sg:pub.10.1186/1746-1596-5-24
24 https://doi.org/10.1002/uog.13246
25 https://doi.org/10.1016/j.ajog.2009.10.891
26 https://doi.org/10.1016/j.ajog.2015.03.032
27 https://doi.org/10.1016/j.fertnstert.2004.12.033
28 https://doi.org/10.1016/j.fertnstert.2009.05.091
29 https://doi.org/10.1016/j.fertnstert.2011.05.050
30 https://doi.org/10.1016/j.fertnstert.2012.03.028
31 https://doi.org/10.1016/j.fertnstert.2012.09.003
32 https://doi.org/10.1016/j.fertnstert.2013.08.044
33 https://doi.org/10.1016/j.placenta.2003.10.009
34 https://doi.org/10.1016/j.placenta.2011.11.021
35 https://doi.org/10.1053/beog.2000.0139
36 https://doi.org/10.1080/14767058.2016.1182483
37 https://doi.org/10.1093/humrep/der394
38 https://doi.org/10.1093/humrep/det272
39 https://doi.org/10.1093/humupd/dmu027
40 https://doi.org/10.1111/j.1600-0412.2012.01516.x
41 https://doi.org/10.1136/bmj.291.6503.1160
42 https://doi.org/10.1210/en.2004-1028
43 https://doi.org/10.3109/10641955.2014.951490
44 https://doi.org/10.3109/14767058.2010.531309
45 https://doi.org/10.3109/14767058.2015.1048431
46 https://doi.org/10.5468/ogs.2017.60.2.154
47 schema:datePublished 2017-12
48 schema:datePublishedReg 2017-12-01
49 schema:description PURPOSE: We aimed to investigate the angiogenic balance in fresh compared to frozen embryo transfers, and among neonates with adverse perinatal outcomes. METHODS: This was a retrospective cohort study. All IVF cycles resulting in a singleton live birth at a university academic fertility center from January 1, 2011, to December 31, 2013, were examined. Concentrations of sFLT-1 and PlGF were measured in previously frozen serum specimens collected during early gestation at approximately 5 weeks gestation. Patients completed an electronic survey to detail perinatal outcome. RESULTS: We identified 152 singleton live births (103 fresh, 49 frozen). Demographic characteristics were similar between the two groups. Ratios of sFlt-1:PlGF were not different between fresh and frozen transfers. Neonates from fresh cycles had a mean birth weight 202 g lighter (p = 0.01) than frozen cycles, after adjusting for gestational age. Among babies born with poor perinatal outcomes, there was a difference in sFlt-1:PlGF ratios after adjusting for race. In non-Asians, infants born small for gestational age (SGA) (< 10th percentile) had significantly higher sFLT-1:PLGF ratio, median ratio (0.21 vs 0.12, p = 0.016). CONCLUSIONS: Fresh transfers were associated with lower birth weight infants compared to frozen transfers. While there was no difference in sFlt-1:PlGF ratios between fresh and frozen transfers, these ratios were significantly lower in SGA infants, suggesting an imbalance in angiogenic markers during placentation.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree false
53 schema:isPartOf N1e93dd21a2284580876b3f99096a2119
54 Ne7bca2e726464db0b64eaf32641b940c
55 sg:journal.1095018
56 schema:name The role of angiogenic markers in adverse perinatal outcomes: fresh versus frozen embryo transfers
57 schema:pagination 1639-1643
58 schema:productId N044335e83bb346baad370a05e8a24e20
59 N3e8242a25cb2401aa1f44960aa7cc47d
60 N49ad87cb3de64cc582e9b068585a2bc7
61 Ncb5f185fc3414e94a390d0d550580fa3
62 Neb43d4b3396c45ac9df853c3c4de6825
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091477592
64 https://doi.org/10.1007/s10815-017-1023-2
65 schema:sdDatePublished 2019-04-10T20:48
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N5c61ff5ef7494edcbef7aef985a55d14
68 schema:url http://link.springer.com/10.1007/s10815-017-1023-2
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N044335e83bb346baad370a05e8a24e20 schema:name readcube_id
73 schema:value d12749a614d9cf590cf20303e685b300aecefa8a9d99bf466dc416ab461d6776
74 rdf:type schema:PropertyValue
75 N10cf29abe0cd4a21a71711bf4025606c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Infant, Small for Gestational Age
77 rdf:type schema:DefinedTerm
78 N1e93dd21a2284580876b3f99096a2119 schema:issueNumber 12
79 rdf:type schema:PublicationIssue
80 N1ebdab84ea784bbb899a28355310806e rdf:first sg:person.012357041465.68
81 rdf:rest Ndcd96a43f5e34232a3823de26cb5f3ab
82 N285630028e9740179c25115dcab8e98c rdf:first sg:person.0751376776.62
83 rdf:rest rdf:nil
84 N3c1ded02cfbc4c57afebb0686e373038 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Adult
86 rdf:type schema:DefinedTerm
87 N3e8242a25cb2401aa1f44960aa7cc47d schema:name dimensions_id
88 schema:value pub.1091477592
89 rdf:type schema:PropertyValue
90 N405333f37bf64fb69ae469e4dd23c38a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Placenta Growth Factor
92 rdf:type schema:DefinedTerm
93 N49ad87cb3de64cc582e9b068585a2bc7 schema:name doi
94 schema:value 10.1007/s10815-017-1023-2
95 rdf:type schema:PropertyValue
96 N4c2d1826a11c43d4834ec74f549790af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Infertility, Female
98 rdf:type schema:DefinedTerm
99 N4fb3fdc9ae12479cbeac69ee3a80cfba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Fertilization in Vitro
101 rdf:type schema:DefinedTerm
102 N55c8549addc4433e8318d5ef0e174f64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Infant, Newborn
104 rdf:type schema:DefinedTerm
105 N5c61ff5ef7494edcbef7aef985a55d14 schema:name Springer Nature - SN SciGraph project
106 rdf:type schema:Organization
107 N60e74bc8f8e545c4acc718be6e065bdd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Live Birth
109 rdf:type schema:DefinedTerm
110 N9341c0e0bd724c2c909bf90d88ab92e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Gestational Age
112 rdf:type schema:DefinedTerm
113 N95ed5793e34d471785a5f1a91e3b3055 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Humans
115 rdf:type schema:DefinedTerm
116 Na506a4a8db2048ceadf35184901c684b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Vascular Endothelial Growth Factor Receptor-1
118 rdf:type schema:DefinedTerm
119 Nb289198217714deb8735d4653dd2f878 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Embryo Transfer
121 rdf:type schema:DefinedTerm
122 Nb90934180a9342c79a6f8c714d58eb44 rdf:first sg:person.015526056223.08
123 rdf:rest Ne5ec6be96dab4630a554a60aecc578ab
124 Nb944df8b33e14707b37850f9a26a7e9f rdf:first sg:person.0772600660.26
125 rdf:rest N285630028e9740179c25115dcab8e98c
126 Ncb5f185fc3414e94a390d0d550580fa3 schema:name nlm_unique_id
127 schema:value 9206495
128 rdf:type schema:PropertyValue
129 Ncc2bb6e2ad604a77aa8862d6587a3c6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Pregnancy
131 rdf:type schema:DefinedTerm
132 Nd3c2df9430ba4a60bfad35a6cc92671d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Female
134 rdf:type schema:DefinedTerm
135 Nd9308958cab740858dbf6417adff70b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Cryopreservation
137 rdf:type schema:DefinedTerm
138 Ndcd96a43f5e34232a3823de26cb5f3ab rdf:first sg:person.01176632731.88
139 rdf:rest Nb90934180a9342c79a6f8c714d58eb44
140 Ne219137300f24f7caeaa325284bbe04c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Pregnancy Outcome
142 rdf:type schema:DefinedTerm
143 Ne3a028a5f2b847d9b5e9dbd0ac00c911 rdf:first sg:person.012357675257.04
144 rdf:rest Nb944df8b33e14707b37850f9a26a7e9f
145 Ne5ec6be96dab4630a554a60aecc578ab rdf:first sg:person.01202315245.46
146 rdf:rest Ne3a028a5f2b847d9b5e9dbd0ac00c911
147 Ne7bca2e726464db0b64eaf32641b940c schema:volumeNumber 34
148 rdf:type schema:PublicationVolume
149 Neb43d4b3396c45ac9df853c3c4de6825 schema:name pubmed_id
150 schema:value 28871422
151 rdf:type schema:PropertyValue
152 Nebc1c02c298345069b1b7f712397a6e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Retrospective Studies
154 rdf:type schema:DefinedTerm
155 Ned62aff0b3ea463c9480746813009c9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Birth Weight
157 rdf:type schema:DefinedTerm
158 Nfccab9a1f0374c6ca1213ba2e502bd50 rdf:first sg:person.014730475623.41
159 rdf:rest N1ebdab84ea784bbb899a28355310806e
160 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
161 schema:name Medical and Health Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
164 schema:name Paediatrics and Reproductive Medicine
165 rdf:type schema:DefinedTerm
166 sg:journal.1095018 schema:issn 1058-0468
167 1573-7330
168 schema:name Journal of Assisted Reproduction and Genetics
169 rdf:type schema:Periodical
170 sg:person.01176632731.88 schema:affiliation https://www.grid.ac/institutes/grid.7132.7
171 schema:familyName Sriprasert
172 schema:givenName Intira
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176632731.88
174 rdf:type schema:Person
175 sg:person.01202315245.46 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
176 schema:familyName Ingles
177 schema:givenName Sue
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202315245.46
179 rdf:type schema:Person
180 sg:person.012357041465.68 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
181 schema:familyName Chan
182 schema:givenName Yen
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357041465.68
184 rdf:type schema:Person
185 sg:person.012357675257.04 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
186 schema:familyName Stanczyk
187 schema:givenName Frank
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357675257.04
189 rdf:type schema:Person
190 sg:person.014730475623.41 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
191 schema:familyName Woo
192 schema:givenName Irene
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014730475623.41
194 rdf:type schema:Person
195 sg:person.015526056223.08 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
196 schema:familyName Louie
197 schema:givenName Kristin
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015526056223.08
199 rdf:type schema:Person
200 sg:person.0751376776.62 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
201 schema:familyName Chung
202 schema:givenName Karine
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751376776.62
204 rdf:type schema:Person
205 sg:person.0772600660.26 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
206 schema:familyName McGinnis
207 schema:givenName Lynda K.
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772600660.26
209 rdf:type schema:Person
210 sg:pub.10.1007/s10815-010-9412-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013989144
211 https://doi.org/10.1007/s10815-010-9412-9
212 rdf:type schema:CreativeWork
213 sg:pub.10.1007/s10815-014-0391-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048196357
214 https://doi.org/10.1007/s10815-014-0391-0
215 rdf:type schema:CreativeWork
216 sg:pub.10.1186/1746-1596-5-24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033212764
217 https://doi.org/10.1186/1746-1596-5-24
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1002/uog.13246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047111611
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/j.ajog.2009.10.891 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047514461
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/j.ajog.2015.03.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031420103
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/j.fertnstert.2004.12.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026906532
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/j.fertnstert.2009.05.091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034468036
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/j.fertnstert.2011.05.050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010312058
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/j.fertnstert.2012.03.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025122818
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/j.fertnstert.2012.09.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019816336
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/j.fertnstert.2013.08.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028350026
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/j.placenta.2003.10.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045983034
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/j.placenta.2011.11.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036945134
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1053/beog.2000.0139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025316321
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1080/14767058.2016.1182483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009513747
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1093/humrep/der394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046247627
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1093/humrep/det272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035616166
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1093/humupd/dmu027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000651051
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1111/j.1600-0412.2012.01516.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036175429
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1136/bmj.291.6503.1160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020123502
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1210/en.2004-1028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064247035
256 rdf:type schema:CreativeWork
257 https://doi.org/10.3109/10641955.2014.951490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034845366
258 rdf:type schema:CreativeWork
259 https://doi.org/10.3109/14767058.2010.531309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020676192
260 rdf:type schema:CreativeWork
261 https://doi.org/10.3109/14767058.2015.1048431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039668860
262 rdf:type schema:CreativeWork
263 https://doi.org/10.5468/ogs.2017.60.2.154 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084470111
264 rdf:type schema:CreativeWork
265 https://www.grid.ac/institutes/grid.42505.36 schema:alternateName University of Southern California
266 schema:name Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine Keck School of Medicine, University of Southern California, 2020 Zonal Avenue, 90033, Los Angeles, CA, USA
267 Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA
268 Department of Obstetrics and Gynecology, LAC+USC Medical Center, University of Southern California, 2020 Zonal Avenue IRD 534, 90033, Los Angeles, CA, USA
269 rdf:type schema:Organization
270 https://www.grid.ac/institutes/grid.7132.7 schema:alternateName Chiang Mai University
271 schema:name Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Southern California, Los Angeles, CA, USA
272 Department of Obstetrics and Gynecology, Division of Reproductive Health, Chiang Mai University, Chiang Mai, Thailand
273 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...