Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Charles Laidi, Jennifer Boisgontier, Amicie de Pierrefeu, Edouard Duchesnay, Sevan Hotier, Marc-Antoine d’Albis, Richard Delorme, Federico Bolognani, Christian Czech, Céline Bouquet, Anouck Amestoy, Julie Petit, Štefan Holiga, Juergen Dukart, Alexandru Gaman, Elie Toledano, Myriam Ly-Le Moal, Isabelle Scheid, Marion Leboyer, Josselin Houenou

ABSTRACT

Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population. More... »

PAGES

1-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10803-018-3807-3

DOI

http://dx.doi.org/10.1007/s10803-018-3807-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110344555

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30511125


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