Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-11

AUTHORS

Alison B. Singer, Gayle C. Windham, Lisa A. Croen, Julie L. Daniels, Brian K. Lee, Yinge Qian, Diana E. Schendel, M. Daniele Fallin, Igor Burstyn

ABSTRACT

Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. More... »

PAGES

3458-3468

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10803-016-2882-6

    DOI

    http://dx.doi.org/10.1007/s10803-016-2882-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1001193033

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27511194


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