The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-10

AUTHORS

Diana E. Schendel, Carolyn DiGuiseppi, Lisa A. Croen, M. Daniele Fallin, Philip L. Reed, Laura A. Schieve, Lisa D. Wiggins, Julie Daniels, Judith Grether, Susan E. Levy, Lisa Miller, Craig Newschaffer, Jennifer Pinto-Martin, Cordelia Robinson, Gayle C. Windham, Aimee Alexander, Arthur S. Aylsworth, Pilar Bernal, Joseph D. Bonner, Lisa Blaskey, Chyrise Bradley, Jack Collins, Casara J. Ferretti, Homayoon Farzadegan, Ellen Giarelli, Marques Harvey, Susan Hepburn, Matthew Herr, Kristina Kaparich, Rebecca Landa, Li-Ching Lee, Brooke Levenseller, Stacey Meyerer, Mohammad H. Rahbar, Andria Ratchford, Ann Reynolds, Steven Rosenberg, Julie Rusyniak, Stuart K. Shapira, Karen Smith, Margaret Souders, Patrick Aaron Thompson, Lisa Young, Marshalyn Yeargin-Allsopp

ABSTRACT

The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal, gastrointestinal, and sociodemographic characteristics. SEED uses a case-control design with population-based ascertainment of children aged 2-5 years with an autism spectrum disorder (ASD) and children in two control groups-one from the general population and one with non-ASD developmental problems. Data from parent-completed questionnaires, interviews, clinical evaluations, biospecimen sampling, and medical record abstraction focus on the prenatal and early postnatal periods. SEED is a valuable resource for testing hypotheses regarding ASD characteristics and causes. More... »

PAGES

2121-2140

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10803-012-1461-8

    DOI

    http://dx.doi.org/10.1007/s10803-012-1461-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1025676615

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22350336


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