Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-03

AUTHORS

Roumen N. Nikolov, Karen E. Bearss, Jelle Lettinga, Craig Erickson, Maria Rodowski, Michael G. Aman, James T. McCracken, Christopher J. McDougle, Elaine Tierney, Benedetto Vitiello, L. Eugene Arnold, Bhavik Shah, David J. Posey, Louise Ritz, Lawrence Scahill

ABSTRACT

Objective To evaluate gastrointestinal (GI) problems in a large, well-characterized sample of children with pervasive developmental disorders (PDDs). Methods One hundred seventy two children entering one of two trials conducted by the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network were assessed comprehensively prior to starting treatment and classified with regard to GI symptoms. Results Thirty nine (22.7%) were positive for GI problems, primarily constipation and diarrhea. Those with GI problems were no different from subjects without GI problems in demographic characteristics, measures of adaptive functioning, or autism symptom severity. Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment. More... »

PAGES

405-413

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10803-008-0637-8

DOI

http://dx.doi.org/10.1007/s10803-008-0637-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011405974

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18791817


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