Brief Report: Plasma Leptin Levels are Elevated in Autism: Association with Early Onset Phenotype? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-01

AUTHORS

Paul Ashwood, Christina Kwong, Robin Hansen, Irva Hertz-Picciotto, Lisa Croen, Paula Krakowiak, Wynn Walker, Isaac N. Pessah, Judy Van de Water

ABSTRACT

There is evidence of both immune dysregulation and autoimmune phenomena in children with autism spectrum disorders (ASD). We examined the hormone/cytokine leptin in 70 children diagnosed with autism (including 37 with regression) compared with 99 age-matched controls including 50 typically developing (TD) controls, 26 siblings without autism, and 23 children with developmental disabilities (DD). Children with autism had significantly higher plasma leptin levels compared with TD controls (p<.006). When further sub-classified into regression or early onset autism, children with early onset autism had significantly higher plasma leptin levels compared with children with regressive autism (p<.042), TD controls (p<.0015), and DD controls (p<.004). We demonstrated an increase in leptin levels in autism, a finding driven by the early onset group. More... »

PAGES

169-175

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10803-006-0353-1

DOI

http://dx.doi.org/10.1007/s10803-006-0353-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007596530

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17347881


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10803-006-0353-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10803-006-0353-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10803-006-0353-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10803-006-0353-1'


 

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