Ascorbic Acid Solubility and Thermodynamic Characteristics in Several Neat Solvents with Temperatures Ranging from 293 to 313 K View Full Text


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Article Info

DATE

2022-06-22

AUTHORS

Leila Nemdili, Rym Guedjali, Samah Habchi, Fatima Mameri, Ouahiba Koutchoukali, Aissa Dehane, Slimane Merouani

ABSTRACT

In this study, the solubility of ascorbic acid (AA) in eight pure solvents, including water, ethanol, methanol, 2-propanol, acetone, acetonitrile, ethyl acetate, and tetrahydrofuran, was measured over the temperature range from 293 K to 313 K. The correlation of the measured solubility data of AA was performed using three non-ideal solution models, namely the modified Apelblat equation, Buchowski–Ksiazczak model (λh equation), and the Van't Hoff model. To understand the dissolution thermodynamic of ascorbic acid, the enthalpy of dissolution ΔHsol, the entropy of dissolution ΔSsol, and the change in Gibbs free energy ΔGsol were determined by the modified forms of the Apelblat equation. The predicted results were in good agreement with the experimental solubility data. Compared to the other thermodynamic models, the computational results reveal that the modified Apelblat equation can give better correlation results for all the selected solvents. The solubility of ascorbic acid increases with rising temperature for all the adopted solvents. In general, the solubility of ascorbic acid in the four polar protic solvents obeys the following order: water > methanol > ethanol > propan-2-ol. On the other hand, the solubility of ascorbic acid in polar aprotic solvents is as follows: tetrahydrofuran > acetone > acetonitrile > ethyl acetate. For all neat solvents, the dissolution process of ascorbic acid was found to be endothermic, entropy-driven, and not spontaneous. More... »

PAGES

123

References to SciGraph publications

  • 2013-11-21. Industrial Production of l-Ascorbic Acid (Vitamin C) and d-Isoascorbic Acid in BIOTECHNOLOGY OF FOOD AND FEED ADDITIVES
  • 2017-06-24. n-type WO3 semiconductor as a cathode electrochromic material for ECD devices in JOURNAL OF MATERIALS SCIENCE: MATERIALS IN ELECTRONICS
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