Fast Terahertz Spectroscopic Holographic Assessment of Optical Properties of Diabetic Blood Plasma View Full Text


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Article Info

DATE

2020-07-18

AUTHORS

Maksim S. Kulya, Evgeniy L. Odlyanitskiy, Quentin Cassar, Ilia A. Mustafin, Valery N. Trukhin, Polina G. Gavrilova, Dmitry V. Korolev, Yulia A. Kononova, Nikolay S. Balbekin, Patrick Mounaix, Jean-Paul Guillet, Nikolay V. Petrov, Olga A. Smolyanskaya

ABSTRACT

A new method for diagnosis of diabetes mellitus is proposed, which uses for measurement a lyophilized blood plasma sample prepared in the form of a pellet. The paper develops a methodology for fast spectroscopic measurements of such pellets with terahertz pulse time-domain holography. For that reason, blood plasma pellets were experimentally measured by terahertz time-domain spectroscopy system in transmission mode and its characteristics were obtained to be then used in numerical simulation of pulse terahertz hologram formation and extraction of its optical properties. Thus, a demonstration of the proof-of-concept was given for the techniques of pellet inspection, which contains information about the presence of glycated proteins, reflecting a diabetic pathology. More... »

PAGES

1041-1056

References to SciGraph publications

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URI

http://scigraph.springernature.com/pub.10.1007/s10762-020-00728-9

DOI

http://dx.doi.org/10.1007/s10762-020-00728-9

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https://app.dimensions.ai/details/publication/pub.1129476371


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