Clade 5 aspartic proteases of Phytophthora infestans are virulence factors implied in RXLR effector cleavage View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03-23

AUTHORS

Charikleia Schoina, Natalie Verbeek-de Kruif, Francine Govers, Klaas Bouwmeester

ABSTRACT

Late blight caused by the oomycete pathogen Phytophthora infestans is one of the most destructive diseases in potato cultivation. To successfully colonize its host, P. infestans secretes a suite of effector proteins that undermine plant immunity, many of which contain a conserved N-terminal RXLR motif that strongly resembles the host targeting motif in effectors of the malaria parasite Plasmodium falciparum. In this study, we focus on three P. infestans clade 5 aspartic proteases (PiAPs) that are homologous to Plasmepsin V (PMV), a Pl. falciparum AP responsible for cleaving effectors prior to translocation into red blood cells. Malaria parasites expressing mutated PMV are impaired in effector translocation and are less virulent. To determine whether clade 5 PiAPs play similar roles in virulence, we characterized P. infestans transformants with either reduced or enhanced PiAP expression levels. Phytophthora infestans transformants with altered PiAP10 or PiAP12 expression were found to be impaired in mycelial growth and sporangia production, and are hampered in their virulence on potato leaves. This was not observed in PiAP11 transformants. Activity assays showed that PiAP10 and PiAP12 possess moderate protease activity, and can potentially cleave the RXLR effector PiAVR4, but not a PiAVR4 version with a mutated RXLR motif. These findings imply that P. infestans APs function in the proteolytic cleavage of RXLR effectors, and warrant further investigation to verify and confirm the role of clade 5 PiAPs in effector processing. More... »

PAGES

1-13

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10658-019-01713-2

DOI

http://dx.doi.org/10.1007/s10658-019-01713-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112964631


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Wageningen University & Research", 
          "id": "https://www.grid.ac/institutes/grid.4818.5", 
          "name": [
            "Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schoina", 
        "givenName": "Charikleia", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wageningen University & Research", 
          "id": "https://www.grid.ac/institutes/grid.4818.5", 
          "name": [
            "Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Verbeek-de Kruif", 
        "givenName": "Natalie", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wageningen University & Research", 
          "id": "https://www.grid.ac/institutes/grid.4818.5", 
          "name": [
            "Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Govers", 
        "givenName": "Francine", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wageningen University & Research", 
          "id": "https://www.grid.ac/institutes/grid.4818.5", 
          "name": [
            "Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bouwmeester", 
        "givenName": "Klaas", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1128/aac.45.7.2008-2017.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000723400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1001897", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000769126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.0020050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003272470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.10.051", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003575107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.10.051", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003575107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/myc.12095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004538255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2008.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005355981", 
          "https://doi.org/10.1038/nprot.2008.73"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms10470", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005851011", 
          "https://doi.org/10.1038/ncomms10470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08728", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007728912", 
          "https://doi.org/10.1038/nature08728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08728", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007728912", 
          "https://doi.org/10.1038/nature08728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.910003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010047828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fpls.2011.00075", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010970217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/038232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013392630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/038232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013392630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/038232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013392630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015554783", 
          "https://doi.org/10.1038/nature06203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.funbio.2011.07.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015886457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fgb.2008.05.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019165808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(88)80672-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020215604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.107.056093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020774069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-199813000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021656419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-199813000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021656419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0095007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022345742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.1005211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023894627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep31420", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026178234", 
          "https://doi.org/10.1038/srep31420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1364-3703.2009.00593.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027512898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1364-3703.2009.00593.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027512898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027633323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1001801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028711076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0121786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032530461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033050459", 
          "https://doi.org/10.1038/nature13555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036803556", 
          "https://doi.org/10.1038/nature08726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036803556", 
          "https://doi.org/10.1038/nature08726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/mpp.12263", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037801721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bc.2002.117", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038134148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1008710700363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042572931", 
          "https://doi.org/10.1023/a:1008710700363"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-12-254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044361684", 
          "https://doi.org/10.1186/1471-2164-12-254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.2004.04136.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046467400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mmbr.67.3.400-428.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047844994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pt.2012.09.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049568948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2010.06.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050892853"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ab.2008.11.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052126215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1094/mpmi-01-15-0022-cr", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060077382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1094/mpmi-08-12-0200-r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060077830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.1005992", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067167504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/psb.23865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072307991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.16.00552", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085471766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/nph.14696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090931622"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03-23", 
    "datePublishedReg": "2019-03-23", 
    "description": "Late blight caused by the oomycete pathogen Phytophthora infestans is one of the most destructive diseases in potato cultivation. To successfully colonize its host, P. infestans secretes a suite of effector proteins that undermine plant immunity, many of which contain a conserved N-terminal RXLR motif that strongly resembles the host targeting motif in effectors of the malaria parasite Plasmodium falciparum. In this study, we focus on three P. infestans clade 5 aspartic proteases (PiAPs) that are homologous to Plasmepsin V (PMV), a Pl. falciparum AP responsible for cleaving effectors prior to translocation into red blood cells. Malaria parasites expressing mutated PMV are impaired in effector translocation and are less virulent. To determine whether clade 5 PiAPs play similar roles in virulence, we characterized P. infestans transformants with either reduced or enhanced PiAP expression levels. Phytophthora infestans transformants with altered PiAP10 or PiAP12 expression were found to be impaired in mycelial growth and sporangia production, and are hampered in their virulence on potato leaves. This was not observed in PiAP11 transformants. Activity assays showed that PiAP10 and PiAP12 possess moderate protease activity, and can potentially cleave the RXLR effector PiAVR4, but not a PiAVR4 version with a mutated RXLR motif. These findings imply that P. infestans APs function in the proteolytic cleavage of RXLR effectors, and warrant further investigation to verify and confirm the role of clade 5 PiAPs in effector processing.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10658-019-01713-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1023051", 
        "issn": [
          "0929-1873", 
          "1573-8469"
        ], 
        "name": "European Journal of Plant Pathology", 
        "type": "Periodical"
      }
    ], 
    "name": "Clade 5 aspartic proteases of Phytophthora infestans are virulence factors implied in RXLR effector cleavage", 
    "pagination": "1-13", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "130d0c316a14b58e9ecc4da9eaed3b9c402afb9efd743993a695f8146f58796f"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10658-019-01713-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112964631"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10658-019-01713-2", 
      "https://app.dimensions.ai/details/publication/pub.1112964631"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000365_0000000365/records_71695_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10658-019-01713-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10658-019-01713-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10658-019-01713-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10658-019-01713-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10658-019-01713-2'


 

This table displays all metadata directly associated to this object as RDF triples.

204 TRIPLES      21 PREDICATES      65 URIs      16 LITERALS      5 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10658-019-01713-2 schema:about anzsrc-for:11
2 anzsrc-for:1108
3 schema:author Nea5a87988b63409e975ee6aabb37e7c4
4 schema:citation sg:pub.10.1023/a:1008710700363
5 sg:pub.10.1038/nature06203
6 sg:pub.10.1038/nature08726
7 sg:pub.10.1038/nature08728
8 sg:pub.10.1038/nature13555
9 sg:pub.10.1038/ncomms10470
10 sg:pub.10.1038/nprot.2008.73
11 sg:pub.10.1038/srep31420
12 sg:pub.10.1186/1471-2164-12-254
13 https://doi.org/10.1016/0014-5793(88)80672-0
14 https://doi.org/10.1016/j.ab.2008.11.007
15 https://doi.org/10.1016/j.cell.2010.06.008
16 https://doi.org/10.1016/j.cell.2011.10.051
17 https://doi.org/10.1016/j.fgb.2008.05.009
18 https://doi.org/10.1016/j.funbio.2011.07.001
19 https://doi.org/10.1016/j.pt.2012.09.004
20 https://doi.org/10.1093/gbe/evu110
21 https://doi.org/10.1094/mpmi-01-15-0022-cr
22 https://doi.org/10.1094/mpmi-08-12-0200-r
23 https://doi.org/10.1097/00002030-199813000-00007
24 https://doi.org/10.1101/038232
25 https://doi.org/10.1101/gr.910003
26 https://doi.org/10.1105/tpc.107.056093
27 https://doi.org/10.1105/tpc.16.00552
28 https://doi.org/10.1111/j.1364-3703.2009.00593.x
29 https://doi.org/10.1111/j.1432-1033.2004.04136.x
30 https://doi.org/10.1111/mpp.12263
31 https://doi.org/10.1111/myc.12095
32 https://doi.org/10.1111/nph.14696
33 https://doi.org/10.1128/aac.45.7.2008-2017.2001
34 https://doi.org/10.1128/mmbr.67.3.400-428.2003
35 https://doi.org/10.1371/journal.pbio.1001801
36 https://doi.org/10.1371/journal.pbio.1001897
37 https://doi.org/10.1371/journal.pone.0095007
38 https://doi.org/10.1371/journal.pone.0121786
39 https://doi.org/10.1371/journal.ppat.0020050
40 https://doi.org/10.1371/journal.ppat.1005211
41 https://doi.org/10.1371/journal.ppat.1005992
42 https://doi.org/10.1515/bc.2002.117
43 https://doi.org/10.3389/fpls.2011.00075
44 https://doi.org/10.4161/psb.23865
45 schema:datePublished 2019-03-23
46 schema:datePublishedReg 2019-03-23
47 schema:description Late blight caused by the oomycete pathogen Phytophthora infestans is one of the most destructive diseases in potato cultivation. To successfully colonize its host, P. infestans secretes a suite of effector proteins that undermine plant immunity, many of which contain a conserved N-terminal RXLR motif that strongly resembles the host targeting motif in effectors of the malaria parasite Plasmodium falciparum. In this study, we focus on three P. infestans clade 5 aspartic proteases (PiAPs) that are homologous to Plasmepsin V (PMV), a Pl. falciparum AP responsible for cleaving effectors prior to translocation into red blood cells. Malaria parasites expressing mutated PMV are impaired in effector translocation and are less virulent. To determine whether clade 5 PiAPs play similar roles in virulence, we characterized P. infestans transformants with either reduced or enhanced PiAP expression levels. Phytophthora infestans transformants with altered PiAP10 or PiAP12 expression were found to be impaired in mycelial growth and sporangia production, and are hampered in their virulence on potato leaves. This was not observed in PiAP11 transformants. Activity assays showed that PiAP10 and PiAP12 possess moderate protease activity, and can potentially cleave the RXLR effector PiAVR4, but not a PiAVR4 version with a mutated RXLR motif. These findings imply that P. infestans APs function in the proteolytic cleavage of RXLR effectors, and warrant further investigation to verify and confirm the role of clade 5 PiAPs in effector processing.
48 schema:genre research_article
49 schema:inLanguage en
50 schema:isAccessibleForFree false
51 schema:isPartOf sg:journal.1023051
52 schema:name Clade 5 aspartic proteases of Phytophthora infestans are virulence factors implied in RXLR effector cleavage
53 schema:pagination 1-13
54 schema:productId N3d3c37a57a5049fa8e81b3f297a5ce86
55 N88e9623facc046eea8ef924b80b93fcc
56 Nc82eb64d5b6e41ce9f0f42ab4c6cf85b
57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112964631
58 https://doi.org/10.1007/s10658-019-01713-2
59 schema:sdDatePublished 2019-04-11T12:59
60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
61 schema:sdPublisher N7d6441b620264f3ca2fa4093b8d2d9e1
62 schema:url https://link.springer.com/10.1007%2Fs10658-019-01713-2
63 sgo:license sg:explorer/license/
64 sgo:sdDataset articles
65 rdf:type schema:ScholarlyArticle
66 N105d2dec8a89473c934c1ea3aea66051 rdf:first Nd0f8df9ec4224a37894b01d491ffc25f
67 rdf:rest rdf:nil
68 N1c3f065517484ef5802cbd68b568abd9 rdf:first N650edb5207ac4194a46adc23b08530b6
69 rdf:rest Ne01cb6801b8b4aa5a8e7119e2233dd37
70 N3d3c37a57a5049fa8e81b3f297a5ce86 schema:name dimensions_id
71 schema:value pub.1112964631
72 rdf:type schema:PropertyValue
73 N650edb5207ac4194a46adc23b08530b6 schema:affiliation https://www.grid.ac/institutes/grid.4818.5
74 schema:familyName Verbeek-de Kruif
75 schema:givenName Natalie
76 rdf:type schema:Person
77 N6cf0096e0efd4216bcac6b170c3fa6fa schema:affiliation https://www.grid.ac/institutes/grid.4818.5
78 schema:familyName Govers
79 schema:givenName Francine
80 rdf:type schema:Person
81 N7d6441b620264f3ca2fa4093b8d2d9e1 schema:name Springer Nature - SN SciGraph project
82 rdf:type schema:Organization
83 N88e9623facc046eea8ef924b80b93fcc schema:name doi
84 schema:value 10.1007/s10658-019-01713-2
85 rdf:type schema:PropertyValue
86 Nc178f47389c544cca5faf3c2513423a1 schema:affiliation https://www.grid.ac/institutes/grid.4818.5
87 schema:familyName Schoina
88 schema:givenName Charikleia
89 rdf:type schema:Person
90 Nc82eb64d5b6e41ce9f0f42ab4c6cf85b schema:name readcube_id
91 schema:value 130d0c316a14b58e9ecc4da9eaed3b9c402afb9efd743993a695f8146f58796f
92 rdf:type schema:PropertyValue
93 Nd0f8df9ec4224a37894b01d491ffc25f schema:affiliation https://www.grid.ac/institutes/grid.4818.5
94 schema:familyName Bouwmeester
95 schema:givenName Klaas
96 rdf:type schema:Person
97 Ne01cb6801b8b4aa5a8e7119e2233dd37 rdf:first N6cf0096e0efd4216bcac6b170c3fa6fa
98 rdf:rest N105d2dec8a89473c934c1ea3aea66051
99 Nea5a87988b63409e975ee6aabb37e7c4 rdf:first Nc178f47389c544cca5faf3c2513423a1
100 rdf:rest N1c3f065517484ef5802cbd68b568abd9
101 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
102 schema:name Medical and Health Sciences
103 rdf:type schema:DefinedTerm
104 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
105 schema:name Medical Microbiology
106 rdf:type schema:DefinedTerm
107 sg:journal.1023051 schema:issn 0929-1873
108 1573-8469
109 schema:name European Journal of Plant Pathology
110 rdf:type schema:Periodical
111 sg:pub.10.1023/a:1008710700363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042572931
112 https://doi.org/10.1023/a:1008710700363
113 rdf:type schema:CreativeWork
114 sg:pub.10.1038/nature06203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015554783
115 https://doi.org/10.1038/nature06203
116 rdf:type schema:CreativeWork
117 sg:pub.10.1038/nature08726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036803556
118 https://doi.org/10.1038/nature08726
119 rdf:type schema:CreativeWork
120 sg:pub.10.1038/nature08728 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007728912
121 https://doi.org/10.1038/nature08728
122 rdf:type schema:CreativeWork
123 sg:pub.10.1038/nature13555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033050459
124 https://doi.org/10.1038/nature13555
125 rdf:type schema:CreativeWork
126 sg:pub.10.1038/ncomms10470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005851011
127 https://doi.org/10.1038/ncomms10470
128 rdf:type schema:CreativeWork
129 sg:pub.10.1038/nprot.2008.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005355981
130 https://doi.org/10.1038/nprot.2008.73
131 rdf:type schema:CreativeWork
132 sg:pub.10.1038/srep31420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026178234
133 https://doi.org/10.1038/srep31420
134 rdf:type schema:CreativeWork
135 sg:pub.10.1186/1471-2164-12-254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044361684
136 https://doi.org/10.1186/1471-2164-12-254
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1016/0014-5793(88)80672-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020215604
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1016/j.ab.2008.11.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052126215
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1016/j.cell.2010.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050892853
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1016/j.cell.2011.10.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003575107
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1016/j.fgb.2008.05.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019165808
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1016/j.funbio.2011.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015886457
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1016/j.pt.2012.09.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049568948
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1093/gbe/evu110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027633323
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1094/mpmi-01-15-0022-cr schema:sameAs https://app.dimensions.ai/details/publication/pub.1060077382
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1094/mpmi-08-12-0200-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1060077830
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1097/00002030-199813000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021656419
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1101/038232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013392630
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1101/gr.910003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010047828
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1105/tpc.107.056093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020774069
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1105/tpc.16.00552 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085471766
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1111/j.1364-3703.2009.00593.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027512898
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1111/j.1432-1033.2004.04136.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046467400
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1111/mpp.12263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037801721
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1111/myc.12095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004538255
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1111/nph.14696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090931622
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1128/aac.45.7.2008-2017.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000723400
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1128/mmbr.67.3.400-428.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047844994
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1371/journal.pbio.1001801 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028711076
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1371/journal.pbio.1001897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000769126
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1371/journal.pone.0095007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022345742
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1371/journal.pone.0121786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032530461
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1371/journal.ppat.0020050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003272470
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1371/journal.ppat.1005211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023894627
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1371/journal.ppat.1005992 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067167504
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1515/bc.2002.117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038134148
197 rdf:type schema:CreativeWork
198 https://doi.org/10.3389/fpls.2011.00075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010970217
199 rdf:type schema:CreativeWork
200 https://doi.org/10.4161/psb.23865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072307991
201 rdf:type schema:CreativeWork
202 https://www.grid.ac/institutes/grid.4818.5 schema:alternateName Wageningen University & Research
203 schema:name Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands
204 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...