Ontology type: schema:ScholarlyArticle Open Access: True
2021-10-08
AUTHORSMakoto Ishimota, Naruto Tomiyama
ABSTRACTTo ascertain the tolerance mechanisms of aquatic organisms to artificial chemicals, intergenerational sensitivity changes of Chironomus yoshimatsui to a carbamate pesticide (pirimicarb) and pharmaceutical chemical (diazepam) were investigated. The larvae (<48-h-old) in each generation were exposed to both chemicals for 48 h and then the surviving chironomids were cultured until the fifth generation (F0–F4) without chemical addition. The 48-h 50% effective concentration (EC50) value of chironomids was determined for each generation. In the pirimicarb treatment group, the EC50 values significantly increased in F3 and F4, and those in the diazepam treatment group slightly increased. Catalase, Cytochrome P450 and hemoglobin (Hb) mRNA levels were monitored to see whether these were related to the trans-generational sensitivity. Although the generalized linear model results showed that the sensitivity to diazepam was slightly increased in the diazepam treatment, we could not find any mRNA levels related to sensitivity alteration. In contrast, the model approach showed that the chironomids exposed to pirimicarb trans-generationally became tolerant with increasing Hb mRNA levels. Therefore, they might decrease their chemical stress by modifying Hb gene transcription. More... »
PAGES2119-2131
http://scigraph.springernature.com/pub.10.1007/s10646-021-02484-5
DOIhttp://dx.doi.org/10.1007/s10646-021-02484-5
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1141724417
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/34623547
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Chemical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/05",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Environmental Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carbamates",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Catalase",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chironomidae",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cytochrome P-450 Enzyme System",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hemoglobins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Larva",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Pharmaceutical Preparations",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Transcription, Genetic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Water Pollutants, Chemical",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "The Institute of Environmental Toxicology, Laboratory of Residue Analysis II, Chemistry Division, Joso-shi, Ibaraki, Japan",
"id": "http://www.grid.ac/institutes/None",
"name": [
"The Institute of Environmental Toxicology, Laboratory of Residue Analysis II, Chemistry Division, Joso-shi, Ibaraki, Japan"
],
"type": "Organization"
},
"familyName": "Ishimota",
"givenName": "Makoto",
"id": "sg:person.012234566024.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012234566024.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Institute of Environmental Toxicology, Laboratory of Residue Analysis II, Chemistry Division, Joso-shi, Ibaraki, Japan",
"id": "http://www.grid.ac/institutes/None",
"name": [
"The Institute of Environmental Toxicology, Laboratory of Residue Analysis II, Chemistry Division, Joso-shi, Ibaraki, Japan"
],
"type": "Organization"
},
"familyName": "Tomiyama",
"givenName": "Naruto",
"id": "sg:person.01325544232.83",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325544232.83"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s11270-018-3765-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1101541241",
"https://doi.org/10.1007/s11270-018-3765-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng983",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044334187",
"https://doi.org/10.1038/ng983"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00208376",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038689965",
"https://doi.org/10.1007/bf00208376"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1134/s0022093012030024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019620209",
"https://doi.org/10.1134/s0022093012030024"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11356-015-4309-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023143523",
"https://doi.org/10.1007/s11356-015-4309-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11270-020-04670-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1128197258",
"https://doi.org/10.1007/s11270-020-04670-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41598-018-28475-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105236563",
"https://doi.org/10.1038/s41598-018-28475-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10646-014-1348-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042747993",
"https://doi.org/10.1007/s10646-014-1348-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00014130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052211002",
"https://doi.org/10.1007/bf00014130"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00227-008-1052-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041027119",
"https://doi.org/10.1007/s00227-008-1052-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41598-017-01961-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085347371",
"https://doi.org/10.1038/s41598-017-01961-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1023/b:emas.0000014503.23761.77",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017364762",
"https://doi.org/10.1023/b:emas.0000014503.23761.77"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00128-015-1719-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018868204",
"https://doi.org/10.1007/s00128-015-1719-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s41936-020-00184-w",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1129416799",
"https://doi.org/10.1186/s41936-020-00184-w"
],
"type": "CreativeWork"
}
],
"datePublished": "2021-10-08",
"datePublishedReg": "2021-10-08",
"description": "To ascertain the tolerance mechanisms of aquatic organisms to artificial chemicals, intergenerational sensitivity changes of Chironomus yoshimatsui to a carbamate pesticide (pirimicarb) and pharmaceutical chemical (diazepam) were investigated. The larvae (<48-h-old) in each generation were exposed to both chemicals for 48\u2009h and then the surviving chironomids were cultured until the fifth generation (F0\u2013F4) without chemical addition. The 48-h 50% effective concentration (EC50) value of chironomids was determined for each generation. In the pirimicarb treatment group, the EC50 values significantly increased in F3 and F4, and those in the diazepam treatment group slightly increased. Catalase, Cytochrome P450 and hemoglobin (Hb) mRNA levels were monitored to see whether these were related to the trans-generational sensitivity. Although the generalized linear model results showed that the sensitivity to diazepam was slightly increased in the diazepam treatment, we could not find any mRNA levels related to sensitivity alteration. In contrast, the model approach showed that the chironomids exposed to pirimicarb trans-generationally became tolerant with increasing Hb mRNA levels. Therefore, they might decrease their chemical stress by modifying Hb gene transcription.",
"genre": "article",
"id": "sg:pub.10.1007/s10646-021-02484-5",
"inLanguage": "en",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1129600",
"issn": [
"0963-9292",
"1573-3017"
],
"name": "Ecotoxicology",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "10",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "30"
}
],
"keywords": [
"pharmaceutical chemicals",
"carbamate pesticides",
"chemical addition",
"artificial chemicals",
"chemicals",
"aquatic organisms",
"effective concentration values",
"concentration values",
"chemical stress",
"trans",
"EC50 values",
"pesticides",
"cytochrome P450",
"Chironomus yoshimatsui",
"sensitivity",
"generation",
"P450",
"group",
"addition",
"values",
"mechanism",
"yoshimatsui",
"CYP450",
"catalase",
"F3",
"F4",
"fifth generation",
"effect",
"organisms",
"contrast",
"results",
"changes",
"model approach",
"approach",
"model results",
"sensitivity changes",
"levels",
"diazepam",
"chironomids",
"treatment",
"alterations",
"tolerance mechanisms",
"stress",
"larvae",
"transcription",
"gene transcription",
"mRNA levels",
"treatment groups",
"diazepam treatment group",
"sensitivity alterations",
"diazepam treatment",
"linear model results"
],
"name": "Generational sensitivity alteration in Chironomus yoshimatsui to carbamate and pharmaceutical chemicals and the effect on Catalase, CYP450, and hemoglobin gene transcription",
"pagination": "2119-2131",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1141724417"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10646-021-02484-5"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"34623547"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10646-021-02484-5",
"https://app.dimensions.ai/details/publication/pub.1141724417"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:38",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_917.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s10646-021-02484-5"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10646-021-02484-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10646-021-02484-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10646-021-02484-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10646-021-02484-5'
This table displays all metadata directly associated to this object as RDF triples.
221 TRIPLES
22 PREDICATES
103 URIs
80 LITERALS
17 BLANK NODES