Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03-29

AUTHORS

Jawad Ahmad, K. Rajender Reddy, Hans L. Tillmann, Paul H. Hayashi, Naga Chalasani, Robert J. Fontana, Victor J. Navarro, Andrew Stolz, Huiman Barnhart, Gavin A. Cloherty, Jay H. Hoofnagle

ABSTRACT

BACKGROUND AND AIMS: The aims were to review the diagnosis, testing and presentation of acute hepatitis C (HCV) in patients initially diagnosed to have drug-induced liver injury (DILI) enrolled in the US DILI Network. METHODS: All patients with suspected DILI underwent testing for competing causes of liver injury and returned for 6-month follow-up. Causality was adjudicated by consensus expert opinion. RESULTS: Between 2004 and 2016, 1518 patients were enrolled and adjudicated and underwent 6 months of follow-up. Initial locally acquired anti-HCV results were available in 1457 (96%), but HCV RNA in only 795 (52%). Stored sera were available for repeat testing, so that results were available on all 1518 patients (1457 for anti-HCV and 1482 for HCV RNA). A total of 104 subjects (6.9%) had evidence of HCV infection-10 positive for HCV RNA alone, 16 for anti-HCV alone and 78 for both. All 104 HCV-positive cases were reviewed, and 23 cases were adjudicated as acute HCV. All presented with acute hepatocellular injury with median ALT 1448 U/L, alkaline phosphatase 232 U/L and total bilirubin 10.8 mg/dL. Twenty-two (96%) patients were jaundiced. While all 23 cases initially had been suspected of having DILI, 19 were adjudicated as acute HCV and not DILI at the 6-month follow-up; while 4 were still considered DILI. CONCLUSIONS: Twenty-three of 1518 (1.5%) cases of suspected DILI were due to acute HCV infection. We recommend that initial and follow-up HCV RNA testing should be performed to exclude HCV in patients with acute hepatocellular injury and suspected DILI. More... »

PAGES

1-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10620-019-05591-w

DOI

http://dx.doi.org/10.1007/s10620-019-05591-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113083084

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30927209


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Icahn School of Medicine at Mount Sinai", 
          "id": "https://www.grid.ac/institutes/grid.59734.3c", 
          "name": [
            "Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 10029, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahmad", 
        "givenName": "Jawad", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pennsylvania", 
          "id": "https://www.grid.ac/institutes/grid.25879.31", 
          "name": [
            "Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reddy", 
        "givenName": "K. Rajender", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "East Carolina University", 
          "id": "https://www.grid.ac/institutes/grid.255364.3", 
          "name": [
            "Division of Gastroenterology, Hepatology and Nutrition, East Carolina University, Greenville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tillmann", 
        "givenName": "Hans L.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hayashi", 
        "givenName": "Paul H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chalasani", 
        "givenName": "Naga", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Michigan\u2013Ann Arbor", 
          "id": "https://www.grid.ac/institutes/grid.214458.e", 
          "name": [
            "Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fontana", 
        "givenName": "Robert J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Albert Einstein Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.239276.b", 
          "name": [
            "Einstein Medical Center, Philadelphia, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Navarro", 
        "givenName": "Victor J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Division of Gastrointestinal and Liver Diseases, Keck School of Medicine of University of Southern California, Los Angeles, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stolz", 
        "givenName": "Andrew", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Duke Clinical Research Institute, Duke University, Durham, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barnhart", 
        "givenName": "Huiman", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abbott (United States)", 
          "id": "https://www.grid.ac/institutes/grid.417574.4", 
          "name": [
            "Volwiler Society, Head Infectious Disease Research, Abbott Laboratories, Lake Bluff, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cloherty", 
        "givenName": "Gavin A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Diabetes and Digestive and Kidney Diseases", 
          "id": "https://www.grid.ac/institutes/grid.419635.c", 
          "name": [
            "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoofnagle", 
        "givenName": "Jay H.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/jmv.24588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001268422"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.23577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006850224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.27978", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010348916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00002018-200932010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013800935", 
          "https://doi.org/10.2165/00002018-200932010-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0895-4356(93)90102-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018878011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2011.07.051", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019490301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.27800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026711398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhin.2016.07.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030084623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2014.03.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045000859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2014.03.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045000859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2015.03.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051254581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2015.03.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051254581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3851/imp2471", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071479680"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3233/isb-2012-0451", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078655556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12864-017-4269-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099598980", 
          "https://doi.org/10.1186/s12864-017-4269-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2105/ajph.2017.304132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099965616"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03-29", 
    "datePublishedReg": "2019-03-29", 
    "description": "BACKGROUND AND AIMS: The aims were to review the diagnosis, testing and presentation of acute hepatitis C (HCV) in patients initially diagnosed to have drug-induced liver injury (DILI) enrolled in the US DILI Network.\nMETHODS: All patients with suspected DILI underwent testing for competing causes of liver injury and returned for 6-month follow-up. Causality was adjudicated by consensus expert opinion.\nRESULTS: Between 2004 and 2016, 1518 patients were enrolled and adjudicated and underwent 6\u00a0months of follow-up. Initial locally acquired anti-HCV results were available in 1457 (96%), but HCV RNA in only 795 (52%). Stored sera were available for repeat testing, so that results were available on all 1518 patients (1457 for anti-HCV and 1482 for HCV RNA). A total of 104 subjects (6.9%) had evidence of HCV infection-10 positive for HCV RNA alone, 16 for anti-HCV alone and 78 for both. All 104 HCV-positive cases were reviewed, and 23 cases were adjudicated as acute HCV. All presented with acute hepatocellular injury with median ALT 1448 U/L, alkaline phosphatase 232\u00a0U/L and total bilirubin 10.8\u00a0mg/dL. Twenty-two (96%) patients were jaundiced. While all 23 cases initially had been suspected of having DILI, 19 were adjudicated as acute HCV and not DILI at the 6-month follow-up; while 4 were still considered DILI.\nCONCLUSIONS: Twenty-three of 1518 (1.5%) cases of suspected DILI were due to acute HCV infection. We recommend that initial and follow-up HCV RNA testing should be performed to exclude HCV in patients with acute hepatocellular injury and suspected DILI.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10620-019-05591-w", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2690338", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018525", 
        "issn": [
          "0163-2116", 
          "1573-2568"
        ], 
        "name": "Digestive Diseases and Sciences", 
        "type": "Periodical"
      }
    ], 
    "name": "Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury", 
    "pagination": "1-8", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "07a36f1ce98fa1872780428972263d6dde7107515faefe6ee4dd2bcd1ce1a65d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30927209"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7902782"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10620-019-05591-w"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113083084"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10620-019-05591-w", 
      "https://app.dimensions.ai/details/publication/pub.1113083084"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000369_0000000369/records_68975_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10620-019-05591-w"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10620-019-05591-w'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10620-019-05591-w'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10620-019-05591-w'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10620-019-05591-w'


 

This table displays all metadata directly associated to this object as RDF triples.

198 TRIPLES      21 PREDICATES      40 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10620-019-05591-w schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N45a9d977d92044c0a165f7d82ecce2d0
4 schema:citation sg:pub.10.1186/s12864-017-4269-2
5 sg:pub.10.2165/00002018-200932010-00005
6 https://doi.org/10.1002/hep.23577
7 https://doi.org/10.1002/hep.27800
8 https://doi.org/10.1002/hep.27978
9 https://doi.org/10.1002/jmv.24588
10 https://doi.org/10.1016/0895-4356(93)90102-7
11 https://doi.org/10.1016/j.jhin.2016.07.021
12 https://doi.org/10.1053/j.gastro.2011.07.051
13 https://doi.org/10.1053/j.gastro.2014.03.045
14 https://doi.org/10.1053/j.gastro.2015.03.006
15 https://doi.org/10.2105/ajph.2017.304132
16 https://doi.org/10.3233/isb-2012-0451
17 https://doi.org/10.3851/imp2471
18 schema:datePublished 2019-03-29
19 schema:datePublishedReg 2019-03-29
20 schema:description BACKGROUND AND AIMS: The aims were to review the diagnosis, testing and presentation of acute hepatitis C (HCV) in patients initially diagnosed to have drug-induced liver injury (DILI) enrolled in the US DILI Network. METHODS: All patients with suspected DILI underwent testing for competing causes of liver injury and returned for 6-month follow-up. Causality was adjudicated by consensus expert opinion. RESULTS: Between 2004 and 2016, 1518 patients were enrolled and adjudicated and underwent 6 months of follow-up. Initial locally acquired anti-HCV results were available in 1457 (96%), but HCV RNA in only 795 (52%). Stored sera were available for repeat testing, so that results were available on all 1518 patients (1457 for anti-HCV and 1482 for HCV RNA). A total of 104 subjects (6.9%) had evidence of HCV infection-10 positive for HCV RNA alone, 16 for anti-HCV alone and 78 for both. All 104 HCV-positive cases were reviewed, and 23 cases were adjudicated as acute HCV. All presented with acute hepatocellular injury with median ALT 1448 U/L, alkaline phosphatase 232 U/L and total bilirubin 10.8 mg/dL. Twenty-two (96%) patients were jaundiced. While all 23 cases initially had been suspected of having DILI, 19 were adjudicated as acute HCV and not DILI at the 6-month follow-up; while 4 were still considered DILI. CONCLUSIONS: Twenty-three of 1518 (1.5%) cases of suspected DILI were due to acute HCV infection. We recommend that initial and follow-up HCV RNA testing should be performed to exclude HCV in patients with acute hepatocellular injury and suspected DILI.
21 schema:genre research_article
22 schema:inLanguage en
23 schema:isAccessibleForFree false
24 schema:isPartOf sg:journal.1018525
25 schema:name Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury
26 schema:pagination 1-8
27 schema:productId N15f7b30edb414315a4ef7df3b18c5ed5
28 N2b8a1d5bc34e4a9aa5bbdfda710d9ca8
29 N5f794617d7774a54b4c34d57a69fa12c
30 N9af67bf58d394fb9a2d55d60d0d4f5e7
31 Nc06c81874d264e35a10df05483321658
32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113083084
33 https://doi.org/10.1007/s10620-019-05591-w
34 schema:sdDatePublished 2019-04-11T13:25
35 schema:sdLicense https://scigraph.springernature.com/explorer/license/
36 schema:sdPublisher Na8b63ef74d594266b6a1d020f0578878
37 schema:url https://link.springer.com/10.1007%2Fs10620-019-05591-w
38 sgo:license sg:explorer/license/
39 sgo:sdDataset articles
40 rdf:type schema:ScholarlyArticle
41 N15f7b30edb414315a4ef7df3b18c5ed5 schema:name doi
42 schema:value 10.1007/s10620-019-05591-w
43 rdf:type schema:PropertyValue
44 N2306fb0314ab40fca8b30492e27a4713 schema:affiliation https://www.grid.ac/institutes/grid.419635.c
45 schema:familyName Hoofnagle
46 schema:givenName Jay H.
47 rdf:type schema:Person
48 N29a68fdaba0f463aaa454f1a6110b68d schema:affiliation https://www.grid.ac/institutes/grid.214458.e
49 schema:familyName Fontana
50 schema:givenName Robert J.
51 rdf:type schema:Person
52 N2b8a1d5bc34e4a9aa5bbdfda710d9ca8 schema:name pubmed_id
53 schema:value 30927209
54 rdf:type schema:PropertyValue
55 N2cce7f0c41924354aa3a4d0fe88e21c7 rdf:first Na79f5e5b347142769c49c1d74fe2a009
56 rdf:rest N8cf45098dae5414fac48a0db19cd7405
57 N31a8d0748ba34843a9728911ec7eb9b3 rdf:first N376646911a164b3c82ec691989ace96f
58 rdf:rest N2cce7f0c41924354aa3a4d0fe88e21c7
59 N376646911a164b3c82ec691989ace96f schema:affiliation https://www.grid.ac/institutes/grid.255364.3
60 schema:familyName Tillmann
61 schema:givenName Hans L.
62 rdf:type schema:Person
63 N44f892d36f544f949ab7108509c8ad43 rdf:first Nb6deae9d7e924e1388dc5ef3a7f2af8a
64 rdf:rest Ned55b879dac34e308671ff2f4745c1a1
65 N45a9d977d92044c0a165f7d82ecce2d0 rdf:first Nd3b07128b1ff45f08e88c1c17ace3422
66 rdf:rest Nbfc52e4281d14cf3a5ae08d7c88ee45f
67 N5de72f40fd02443a8c8e8d095853498b rdf:first N2306fb0314ab40fca8b30492e27a4713
68 rdf:rest rdf:nil
69 N5f794617d7774a54b4c34d57a69fa12c schema:name readcube_id
70 schema:value 07a36f1ce98fa1872780428972263d6dde7107515faefe6ee4dd2bcd1ce1a65d
71 rdf:type schema:PropertyValue
72 N5fbb06ffd69f4872873507e6f7d9e721 schema:affiliation https://www.grid.ac/institutes/grid.25879.31
73 schema:familyName Reddy
74 schema:givenName K. Rajender
75 rdf:type schema:Person
76 N64605bab08384116810c4d4725f4cf9a schema:affiliation https://www.grid.ac/institutes/grid.417574.4
77 schema:familyName Cloherty
78 schema:givenName Gavin A.
79 rdf:type schema:Person
80 N8cf45098dae5414fac48a0db19cd7405 rdf:first Nae6d2434343a45a0bc3e6145c7141dc7
81 rdf:rest N986cdd05e4954c36ad67f8c92c6e0ca0
82 N986cdd05e4954c36ad67f8c92c6e0ca0 rdf:first N29a68fdaba0f463aaa454f1a6110b68d
83 rdf:rest N44f892d36f544f949ab7108509c8ad43
84 N998bcf24e8004845b8d55d90b70d3f7a schema:affiliation https://www.grid.ac/institutes/grid.42505.36
85 schema:familyName Stolz
86 schema:givenName Andrew
87 rdf:type schema:Person
88 N9af67bf58d394fb9a2d55d60d0d4f5e7 schema:name dimensions_id
89 schema:value pub.1113083084
90 rdf:type schema:PropertyValue
91 Na79f5e5b347142769c49c1d74fe2a009 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
92 schema:familyName Hayashi
93 schema:givenName Paul H.
94 rdf:type schema:Person
95 Na8b63ef74d594266b6a1d020f0578878 schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 Nae6d2434343a45a0bc3e6145c7141dc7 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
98 schema:familyName Chalasani
99 schema:givenName Naga
100 rdf:type schema:Person
101 Nb6deae9d7e924e1388dc5ef3a7f2af8a schema:affiliation https://www.grid.ac/institutes/grid.239276.b
102 schema:familyName Navarro
103 schema:givenName Victor J.
104 rdf:type schema:Person
105 Nbd3cb000e91b43488327de4e633ff736 rdf:first Nfb70ee758d114a989048f7e2a9e1da20
106 rdf:rest Nd820a4d90a1e45a582d864df4832ad6a
107 Nbfc52e4281d14cf3a5ae08d7c88ee45f rdf:first N5fbb06ffd69f4872873507e6f7d9e721
108 rdf:rest N31a8d0748ba34843a9728911ec7eb9b3
109 Nc06c81874d264e35a10df05483321658 schema:name nlm_unique_id
110 schema:value 7902782
111 rdf:type schema:PropertyValue
112 Nd3b07128b1ff45f08e88c1c17ace3422 schema:affiliation https://www.grid.ac/institutes/grid.59734.3c
113 schema:familyName Ahmad
114 schema:givenName Jawad
115 rdf:type schema:Person
116 Nd820a4d90a1e45a582d864df4832ad6a rdf:first N64605bab08384116810c4d4725f4cf9a
117 rdf:rest N5de72f40fd02443a8c8e8d095853498b
118 Ned55b879dac34e308671ff2f4745c1a1 rdf:first N998bcf24e8004845b8d55d90b70d3f7a
119 rdf:rest Nbd3cb000e91b43488327de4e633ff736
120 Nfb70ee758d114a989048f7e2a9e1da20 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
121 schema:familyName Barnhart
122 schema:givenName Huiman
123 rdf:type schema:Person
124 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
125 schema:name Medical and Health Sciences
126 rdf:type schema:DefinedTerm
127 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
128 schema:name Clinical Sciences
129 rdf:type schema:DefinedTerm
130 sg:grant.2690338 http://pending.schema.org/fundedItem sg:pub.10.1007/s10620-019-05591-w
131 rdf:type schema:MonetaryGrant
132 sg:journal.1018525 schema:issn 0163-2116
133 1573-2568
134 schema:name Digestive Diseases and Sciences
135 rdf:type schema:Periodical
136 sg:pub.10.1186/s12864-017-4269-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099598980
137 https://doi.org/10.1186/s12864-017-4269-2
138 rdf:type schema:CreativeWork
139 sg:pub.10.2165/00002018-200932010-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013800935
140 https://doi.org/10.2165/00002018-200932010-00005
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1002/hep.23577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006850224
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1002/hep.27800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026711398
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1002/hep.27978 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010348916
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1002/jmv.24588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001268422
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1016/0895-4356(93)90102-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018878011
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1016/j.jhin.2016.07.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030084623
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1053/j.gastro.2011.07.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019490301
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1053/j.gastro.2014.03.045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045000859
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1053/j.gastro.2015.03.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051254581
159 rdf:type schema:CreativeWork
160 https://doi.org/10.2105/ajph.2017.304132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099965616
161 rdf:type schema:CreativeWork
162 https://doi.org/10.3233/isb-2012-0451 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078655556
163 rdf:type schema:CreativeWork
164 https://doi.org/10.3851/imp2471 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071479680
165 rdf:type schema:CreativeWork
166 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
167 schema:name Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, USA
168 rdf:type schema:Organization
169 https://www.grid.ac/institutes/grid.214458.e schema:alternateName University of Michigan–Ann Arbor
170 schema:name Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, USA
171 rdf:type schema:Organization
172 https://www.grid.ac/institutes/grid.239276.b schema:alternateName Albert Einstein Medical Center
173 schema:name Einstein Medical Center, Philadelphia, USA
174 rdf:type schema:Organization
175 https://www.grid.ac/institutes/grid.255364.3 schema:alternateName East Carolina University
176 schema:name Division of Gastroenterology, Hepatology and Nutrition, East Carolina University, Greenville, USA
177 rdf:type schema:Organization
178 https://www.grid.ac/institutes/grid.257413.6 schema:alternateName Indiana University – Purdue University Indianapolis
179 schema:name Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
180 rdf:type schema:Organization
181 https://www.grid.ac/institutes/grid.25879.31 schema:alternateName University of Pennsylvania
182 schema:name Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, USA
183 rdf:type schema:Organization
184 https://www.grid.ac/institutes/grid.26009.3d schema:alternateName Duke University
185 schema:name Duke Clinical Research Institute, Duke University, Durham, USA
186 rdf:type schema:Organization
187 https://www.grid.ac/institutes/grid.417574.4 schema:alternateName Abbott (United States)
188 schema:name Volwiler Society, Head Infectious Disease Research, Abbott Laboratories, Lake Bluff, USA
189 rdf:type schema:Organization
190 https://www.grid.ac/institutes/grid.419635.c schema:alternateName National Institute of Diabetes and Digestive and Kidney Diseases
191 schema:name National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, USA
192 rdf:type schema:Organization
193 https://www.grid.ac/institutes/grid.42505.36 schema:alternateName University of Southern California
194 schema:name Division of Gastrointestinal and Liver Diseases, Keck School of Medicine of University of Southern California, Los Angeles, USA
195 rdf:type schema:Organization
196 https://www.grid.ac/institutes/grid.59734.3c schema:alternateName Icahn School of Medicine at Mount Sinai
197 schema:name Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 10029, New York, NY, USA
198 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...