Ontology type: schema:ScholarlyArticle
2014-05-15
AUTHORSTakashi Hisabe, Kenshi Yao, Kentaro Imamura, Hiroshi Ishihara, Fumihito Hirai, Toshiyuki Matsui, Akinori Iwashita
ABSTRACTBackgroundThe presence of a white opaque substance (WOS) on magnifying endoscopy (ME) with narrow-band imaging (NBI) has been reported for gastric epithelial neoplasms, but the presence of WOS in colorectal epithelial neoplasms has not been investigated.AimsThe purpose of this study was to determine whether WOS is present in colorectal epithelial neoplasms and to clarify its clinical significance.MethodsA total of 590 colorectal epithelial neoplasms from 368 consecutive patients were retrospectively analyzed using prospectively collected data. Presence or absence of WOS in colorectal epithelial neoplasms was recorded based on the findings of ME with NBI.ResultsWhite opaque substance was present in 236 of the 590 (40 %) colorectal epithelial neoplasms. Compared with WOS-negative patients, WOS-positive patients showed significantly larger tumors (p < 0.0001) and significantly more tumors in the proximal colon (p = 0.0003). WOS was more frequently present in carcinomas (66.0 %) than in adenomas (31.8 %; p < 0.0001). WOS was also more frequent in submucosal carcinomas (75.9 %) than in intramucosal carcinomas (59.0 %; p = 0.0380).ConclusionsThis study confirmed the presence of WOS in colorectal epithelial neoplasms, and prevalence increased with the progression of cancer, from adenoma to carcinoma and from intramucosal carcinoma to submucosal carcinoma. More... »
PAGES2544-2549
http://scigraph.springernature.com/pub.10.1007/s10620-014-3204-5
DOIhttp://dx.doi.org/10.1007/s10620-014-3204-5
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/24828918
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