White Opaque Substance Visualized Using Magnifying Endoscopy with Narrow-Band Imaging in Colorectal Epithelial Neoplasms View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-05-15

AUTHORS

Takashi Hisabe, Kenshi Yao, Kentaro Imamura, Hiroshi Ishihara, Fumihito Hirai, Toshiyuki Matsui, Akinori Iwashita

ABSTRACT

BackgroundThe presence of a white opaque substance (WOS) on magnifying endoscopy (ME) with narrow-band imaging (NBI) has been reported for gastric epithelial neoplasms, but the presence of WOS in colorectal epithelial neoplasms has not been investigated.AimsThe purpose of this study was to determine whether WOS is present in colorectal epithelial neoplasms and to clarify its clinical significance.MethodsA total of 590 colorectal epithelial neoplasms from 368 consecutive patients were retrospectively analyzed using prospectively collected data. Presence or absence of WOS in colorectal epithelial neoplasms was recorded based on the findings of ME with NBI.ResultsWhite opaque substance was present in 236 of the 590 (40 %) colorectal epithelial neoplasms. Compared with WOS-negative patients, WOS-positive patients showed significantly larger tumors (p < 0.0001) and significantly more tumors in the proximal colon (p = 0.0003). WOS was more frequently present in carcinomas (66.0 %) than in adenomas (31.8 %; p < 0.0001). WOS was also more frequent in submucosal carcinomas (75.9 %) than in intramucosal carcinomas (59.0 %; p = 0.0380).ConclusionsThis study confirmed the presence of WOS in colorectal epithelial neoplasms, and prevalence increased with the progression of cancer, from adenoma to carcinoma and from intramucosal carcinoma to submucosal carcinoma. More... »

PAGES

2544-2549

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10620-014-3204-5

DOI

http://dx.doi.org/10.1007/s10620-014-3204-5

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https://app.dimensions.ai/details/publication/pub.1051480028

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24828918


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