Evaluation of Different Bowel Preparations for Small Bowel Capsule Endoscopy: A Prospective, Randomized, Controlled Study View Full Text


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Article Info

DATE

2011-04-10

AUTHORS

Vicente Pons Beltrán, Begoña González Suárez, Cecilia González Asanza, Enrique Pérez-Cuadrado, Servando Fernández Diez, Iñaqui Fernández-Urién, Alfredo Mata Bilbao, Jorge Carlos Espinós Pérez, Maria Jose Pérez Grueso, Lidia Argüello Viudez, Julio Valle Muñoz, Fernando Carballo Alvarez, Miguel Muñoz-Navas, Jose Llach Vila, Juan Andrés Ramírez Armengol, Joaquin Balanzó Tintoré, Teresa Sala Felis, Pedro Menchen Fernández-Pacheco

ABSTRACT

Background and Study AimsTo obtain an adequate view of the whole small intestine during capsule endoscopy (CE) a clear liquid diet and overnight fasting is recommended. However, intestinal content can hamper vision in spite of these measures. Our aim was to evaluate tolerance and degree of intestinal cleanliness during CE following three types of bowel preparation.Patients and MethodsThis was a prospective, multicenter, randomized, controlled study. Two-hundred ninety-one patients underwent one of the following preparations: 4 L of clear liquids (CL) (group A; 92 patients); 90 mL of aqueous sodium phosphate (group B; 89 patients); or 4 L of a polyethylene glycol electrolyte solution (group C; 92 patients). The degree of cleanliness of the small bowel was classified by blinded examiners according to four categories (excellent, good, fair or poor). The degree of patient satisfaction, gastric and small bowel transit times, and diagnostic yield were measured.ResultsThe degree of cleanliness did not differ significantly between the groups (P = 0.496). Interobserver concordance was fair (k = 0.38). No significant differences were detected between the diagnostic yields of the CE (P = 0.601). Gastric transit time was 35.7 ± 3.7 min (group A), 46.1 ± 8.6 min (group B) and 34.6 ± 5.0 min (group C) (P = 0.417). Small-intestinal transit time was 276.9 ± 10.7 min (group A), 249.7 ± 13.1 min (group B) and 245.6 ± 11.6 min (group C) (P = 0.120). CL was the best tolerated preparation. Compliance with the bowel preparation regimen was lowest in group C (P = 0.008).ConclusionsA clear liquid diet and overnight fasting is sufficient to achieve an adequate level of cleanliness and is better tolerated by patients than other forms of preparation. More... »

PAGES

2900-2905

References to SciGraph publications

  • 2007-11-15. Purgative Bowel Cleansing Combined With Simethicone Improves Capsule Endoscopy Imaging in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10620-011-1693-z

    DOI

    http://dx.doi.org/10.1007/s10620-011-1693-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1005705509

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21479818


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        "description": "Background and Study AimsTo obtain an adequate view of the whole small intestine during capsule endoscopy (CE) a clear liquid diet and overnight fasting is recommended. However, intestinal content can hamper vision in spite of these measures. Our aim was to evaluate tolerance and degree of intestinal cleanliness during CE following three types of bowel preparation.Patients and MethodsThis was a prospective, multicenter, randomized, controlled study. Two-hundred ninety-one patients underwent one of the following preparations: 4\u00a0L of clear liquids (CL) (group A; 92 patients); 90\u00a0mL of aqueous sodium phosphate (group B; 89 patients); or 4\u00a0L of a polyethylene glycol electrolyte solution (group C; 92 patients). The degree of cleanliness of the small bowel was classified by blinded examiners according to four categories (excellent, good, fair or poor). The degree of patient satisfaction, gastric and small bowel transit times, and diagnostic yield were measured.ResultsThe degree of cleanliness did not differ significantly between the groups (P\u00a0=\u00a00.496). Interobserver concordance was fair (k\u00a0=\u00a00.38). No significant differences were detected between the diagnostic yields of the CE (P\u00a0=\u00a00.601). Gastric transit time was 35.7\u00a0\u00b1\u00a03.7\u00a0min (group A), 46.1\u00a0\u00b1\u00a08.6\u00a0min (group B) and 34.6\u00a0\u00b1\u00a05.0\u00a0min (group C) (P\u00a0=\u00a00.417). Small-intestinal transit time was 276.9\u00a0\u00b1\u00a010.7\u00a0min (group A), 249.7\u00a0\u00b1\u00a013.1\u00a0min (group B) and 245.6\u00a0\u00b1\u00a011.6\u00a0min (group C) (P\u00a0=\u00a00.120). CL was the best tolerated preparation. Compliance with the bowel preparation regimen was lowest in group C (P\u00a0=\u00a00.008).ConclusionsA clear liquid diet and overnight fasting is sufficient to achieve an adequate level of cleanliness and is better tolerated by patients than other forms of preparation.", 
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    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10620-011-1693-z'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10620-011-1693-z'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10620-011-1693-z'


     

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    22 schema:description Background and Study AimsTo obtain an adequate view of the whole small intestine during capsule endoscopy (CE) a clear liquid diet and overnight fasting is recommended. However, intestinal content can hamper vision in spite of these measures. Our aim was to evaluate tolerance and degree of intestinal cleanliness during CE following three types of bowel preparation.Patients and MethodsThis was a prospective, multicenter, randomized, controlled study. Two-hundred ninety-one patients underwent one of the following preparations: 4 L of clear liquids (CL) (group A; 92 patients); 90 mL of aqueous sodium phosphate (group B; 89 patients); or 4 L of a polyethylene glycol electrolyte solution (group C; 92 patients). The degree of cleanliness of the small bowel was classified by blinded examiners according to four categories (excellent, good, fair or poor). The degree of patient satisfaction, gastric and small bowel transit times, and diagnostic yield were measured.ResultsThe degree of cleanliness did not differ significantly between the groups (P = 0.496). Interobserver concordance was fair (k = 0.38). No significant differences were detected between the diagnostic yields of the CE (P = 0.601). Gastric transit time was 35.7 ± 3.7 min (group A), 46.1 ± 8.6 min (group B) and 34.6 ± 5.0 min (group C) (P = 0.417). Small-intestinal transit time was 276.9 ± 10.7 min (group A), 249.7 ± 13.1 min (group B) and 245.6 ± 11.6 min (group C) (P = 0.120). CL was the best tolerated preparation. Compliance with the bowel preparation regimen was lowest in group C (P = 0.008).ConclusionsA clear liquid diet and overnight fasting is sufficient to achieve an adequate level of cleanliness and is better tolerated by patients than other forms of preparation.
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