Poor Response to Pegylated Interferon and Ribavirin in Older Women Infected with Hepatitis C Virus of Genotype 1b in High ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-06

AUTHORS

Hitomi Sezaki, Fumitaka Suzuki, Yusuke Kawamura, Hiromi Yatsuji, Tetsuya Hosaka, Norio Akuta, Masahiro Kobayashi, Yoshiyuki Suzuki, Satoshi Saitoh, Yasuji Arase, Kenji Ikeda, Yuzo Miyakawa, Hiromitsu Kumada

ABSTRACT

BACKGROUND: Response to treatment in patients with chronic hepatitis C, with reference to age and gender, has not been examined fully. AIM: The influence of gender and age on treatment with pegylated interferon (PEG-IFN) and ribavirin was evaluated in a retrospective study. METHODS: PEG-IFN and ribavirin were given for 48 weeks to 179 men and 121 women infected with hepatitis C virus (HCV) of genotype 1b in high viral loads (>100 kIU/ml). RESULTS: Sustained virological response at 24 weeks after treatment was poorer in women than men who were aged >or=50 years (22% vs 53%, P < 0.001). Among the patients aged >or=50 years who had received >or=80% of the doses of PEG-IFN, ribavirin, or both, women responded less often than men (26% vs 64%, P < 0.001; 33% vs 61%, P = 0.022; and 32% vs 63%, P = 0.016; respectively). In multivariate analysis, male gender, retention of indocyanine green, ribavirin dose and compliance with therapy increased sustained virological response. CONCLUSIONS: Response to combined PEG-IFN and ribavirin is poorer in female than male patients with hepatitis C who are aged >or=50 years, irrespective of compliance with treatment. Low estrogen levels in older women could be responsible for their impaired response to PEG-IFN and ribavirin. More... »

PAGES

1317

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10620-008-0500-y

DOI

http://dx.doi.org/10.1007/s10620-008-0500-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034878037

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18958621


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antiviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepacivirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interferon alpha-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interferon-alpha", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polyethylene Glycols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ribavirin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Characteristics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Viral Load", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sezaki", 
        "givenName": "Hitomi", 
        "id": "sg:person.01052350244.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052350244.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Fumitaka", 
        "id": "sg:person.0760512552.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760512552.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawamura", 
        "givenName": "Yusuke", 
        "id": "sg:person.01110222601.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110222601.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yatsuji", 
        "givenName": "Hiromi", 
        "id": "sg:person.01277062110.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277062110.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hosaka", 
        "givenName": "Tetsuya", 
        "id": "sg:person.0662772733.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662772733.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akuta", 
        "givenName": "Norio", 
        "id": "sg:person.01111770263.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111770263.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kobayashi", 
        "givenName": "Masahiro", 
        "id": "sg:person.01237074644.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237074644.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Yoshiyuki", 
        "id": "sg:person.012355406644.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012355406644.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saitoh", 
        "givenName": "Satoshi", 
        "id": "sg:person.016377110462.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016377110462.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arase", 
        "givenName": "Yasuji", 
        "id": "sg:person.01351140444.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351140444.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikeda", 
        "givenName": "Kenji", 
        "id": "sg:person.0777635301.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777635301.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Miyakawa Memorial Research Foundation", 
          "id": "https://www.grid.ac/institutes/grid.480868.a", 
          "name": [
            "Miyakawa Memorial Research Foundation, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyakawa", 
        "givenName": "Yuzo", 
        "id": "sg:person.0762121603.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762121603.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Toranomon Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410813.f", 
          "name": [
            "Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumada", 
        "givenName": "Hiromitsu", 
        "id": "sg:person.0625534344.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625534344.87"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00535-003-1363-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004562363", 
          "https://doi.org/10.1007/s00535-003-1363-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00535-003-1363-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004562363", 
          "https://doi.org/10.1007/s00535-003-1363-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.510290307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004646384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.20463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004698190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199811193392101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004715205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2006.06.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006919368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2006.06.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006919368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/lt.500030504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007147531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000087273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010517484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000087273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010517484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-8278(99)80369-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011214576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-8278(99)80369-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011214576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa020047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013273688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2893.2000.00233.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013939427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/jhep.2000.8169", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015241367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.51.2.248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015401650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cgh.2006.05.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015713031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.158.2.177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018087658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/368217", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022668082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840360706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023592415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840360706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023592415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1440-1746.2000.02368.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024636825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1440-1746.2000.02060.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025869053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1440-1746.2000.02060.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025869053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840190505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034162200"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20979", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037907405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/jlts.2003.50242", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037929478"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199302183280708", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039848312"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1872-034x.2007.00132.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041980279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(96)07642-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043216718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1478-3231.2006.01354.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043464355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000087270", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045924056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000087270", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045924056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20414", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046753742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20414", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046753742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(98)07124-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046778281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199909163411202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048178958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199904223401602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049024120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(95)90207-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051419815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(89)91629-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052595023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1998.tb00150.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053504989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0676.1998.tb00150.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053504989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2000-9505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057405288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.285.5424.26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062565771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.83.7.2266", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064300282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-132-4-200002150-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073703937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-140-5-200403020-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073707203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083116052", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-06", 
    "datePublishedReg": "2009-06-01", 
    "description": "BACKGROUND: Response to treatment in patients with chronic hepatitis C, with reference to age and gender, has not been examined fully.\nAIM: The influence of gender and age on treatment with pegylated interferon (PEG-IFN) and ribavirin was evaluated in a retrospective study.\nMETHODS: PEG-IFN and ribavirin were given for 48 weeks to 179 men and 121 women infected with hepatitis C virus (HCV) of genotype 1b in high viral loads (>100 kIU/ml).\nRESULTS: Sustained virological response at 24 weeks after treatment was poorer in women than men who were aged >or=50 years (22% vs 53%, P < 0.001). Among the patients aged >or=50 years who had received >or=80% of the doses of PEG-IFN, ribavirin, or both, women responded less often than men (26% vs 64%, P < 0.001; 33% vs 61%, P = 0.022; and 32% vs 63%, P = 0.016; respectively). In multivariate analysis, male gender, retention of indocyanine green, ribavirin dose and compliance with therapy increased sustained virological response.\nCONCLUSIONS: Response to combined PEG-IFN and ribavirin is poorer in female than male patients with hepatitis C who are aged >or=50 years, irrespective of compliance with treatment. Low estrogen levels in older women could be responsible for their impaired response to PEG-IFN and ribavirin.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10620-008-0500-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018525", 
        "issn": [
          "0163-2116", 
          "1573-2568"
        ], 
        "name": "Digestive Diseases and Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "54"
      }
    ], 
    "name": "Poor Response to Pegylated Interferon and Ribavirin in Older Women Infected with Hepatitis C Virus of Genotype 1b in High Viral Loads", 
    "pagination": "1317", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10620-008-0500-y"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a6254b900772490c5e4f4c5d4cd319088f756f9c28607d04fd03b6993567c6b7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034878037"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7902782"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18958621"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10620-008-0500-y", 
      "https://app.dimensions.ai/details/publication/pub.1034878037"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000376_0000000376/records_56158_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s10620-008-0500-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10620-008-0500-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10620-008-0500-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10620-008-0500-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10620-008-0500-y'


 

This table displays all metadata directly associated to this object as RDF triples.

353 TRIPLES      21 PREDICATES      88 URIs      41 LITERALS      29 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10620-008-0500-y schema:about N031886476ec24e51b53c2ff920d894dd
2 N054ac629523040e6a9b6b5a7c35a893c
3 N166002015b024816b527cc2390193ec0
4 N29efbd8dd903499f8b318a76b51da94b
5 N2e6bf644ecb8483a995dad8d2099af6c
6 N48ccd559c7a34873aa226e9425c014f0
7 N4b8f9b24e5c0481fb6789be152d47545
8 N4c32d32e39f94f1a80fb88e62ea5fcc0
9 N50ec06bd1d3a4fc59eee55c8fe4282bb
10 N6a810c4398d1457591bda3b8e0290f45
11 N6af532475d0a4fdcb70d248e1828a9e4
12 N752d5297968645a199caaae3f61d8324
13 N7610309939184ac3b56515dcba872659
14 N8277b2da396a4c368d9930617b3a4fb7
15 N83c798e741d647dd85a22ca94cf02735
16 N9a208ee072cd43faa7381eb506775d8b
17 Na7bff134916d4faead38ad82be1878e5
18 Nda1fdc7b62a9494b8599f9d176bfea4d
19 Ndff459916f2a41abac9892932412d892
20 Nfb569f49c9d0488283afd36569958000
21 anzsrc-for:11
22 anzsrc-for:1103
23 schema:author N5309015417e744019366a5bde35395cf
24 schema:citation sg:pub.10.1007/s00535-003-1363-9
25 https://app.dimensions.ai/details/publication/pub.1083116052
26 https://doi.org/10.1001/archinte.158.2.177
27 https://doi.org/10.1002/hep.1840190505
28 https://doi.org/10.1002/hep.1840360706
29 https://doi.org/10.1002/hep.20463
30 https://doi.org/10.1002/hep.510290307
31 https://doi.org/10.1002/jmv.20414
32 https://doi.org/10.1002/jmv.20979
33 https://doi.org/10.1002/lt.500030504
34 https://doi.org/10.1016/0016-5085(89)91629-6
35 https://doi.org/10.1016/0016-5085(95)90207-4
36 https://doi.org/10.1016/j.cgh.2006.05.028
37 https://doi.org/10.1016/s0140-6736(96)07642-8
38 https://doi.org/10.1016/s0140-6736(98)07124-4
39 https://doi.org/10.1016/s0168-8278(99)80369-9
40 https://doi.org/10.1046/j.1365-2893.2000.00233.x
41 https://doi.org/10.1046/j.1440-1746.2000.02060.x
42 https://doi.org/10.1046/j.1440-1746.2000.02368.x
43 https://doi.org/10.1053/j.gastro.2006.06.008
44 https://doi.org/10.1053/jhep.2000.8169
45 https://doi.org/10.1053/jlts.2003.50242
46 https://doi.org/10.1055/s-2000-9505
47 https://doi.org/10.1056/nejm199302183280708
48 https://doi.org/10.1056/nejm199811193392101
49 https://doi.org/10.1056/nejm199904223401602
50 https://doi.org/10.1056/nejm199909163411202
51 https://doi.org/10.1056/nejmoa020047
52 https://doi.org/10.1086/368217
53 https://doi.org/10.1111/j.1478-3231.2006.01354.x
54 https://doi.org/10.1111/j.1600-0676.1998.tb00150.x
55 https://doi.org/10.1111/j.1872-034x.2007.00132.x
56 https://doi.org/10.1126/science.285.5424.26
57 https://doi.org/10.1136/gut.51.2.248
58 https://doi.org/10.1159/000087270
59 https://doi.org/10.1159/000087273
60 https://doi.org/10.1210/jc.83.7.2266
61 https://doi.org/10.7326/0003-4819-132-4-200002150-00008
62 https://doi.org/10.7326/0003-4819-140-5-200403020-00010
63 schema:datePublished 2009-06
64 schema:datePublishedReg 2009-06-01
65 schema:description BACKGROUND: Response to treatment in patients with chronic hepatitis C, with reference to age and gender, has not been examined fully. AIM: The influence of gender and age on treatment with pegylated interferon (PEG-IFN) and ribavirin was evaluated in a retrospective study. METHODS: PEG-IFN and ribavirin were given for 48 weeks to 179 men and 121 women infected with hepatitis C virus (HCV) of genotype 1b in high viral loads (>100 kIU/ml). RESULTS: Sustained virological response at 24 weeks after treatment was poorer in women than men who were aged >or=50 years (22% vs 53%, P < 0.001). Among the patients aged >or=50 years who had received >or=80% of the doses of PEG-IFN, ribavirin, or both, women responded less often than men (26% vs 64%, P < 0.001; 33% vs 61%, P = 0.022; and 32% vs 63%, P = 0.016; respectively). In multivariate analysis, male gender, retention of indocyanine green, ribavirin dose and compliance with therapy increased sustained virological response. CONCLUSIONS: Response to combined PEG-IFN and ribavirin is poorer in female than male patients with hepatitis C who are aged >or=50 years, irrespective of compliance with treatment. Low estrogen levels in older women could be responsible for their impaired response to PEG-IFN and ribavirin.
66 schema:genre research_article
67 schema:inLanguage en
68 schema:isAccessibleForFree false
69 schema:isPartOf N2fd9e447bff04d05be521592e45b4e5f
70 N480cf8a43fee451696b7cbd54c1a1c72
71 sg:journal.1018525
72 schema:name Poor Response to Pegylated Interferon and Ribavirin in Older Women Infected with Hepatitis C Virus of Genotype 1b in High Viral Loads
73 schema:pagination 1317
74 schema:productId N027a420383724cb889670558630790fe
75 N7fcf93bc2c0c41cfaad5083e16731994
76 N8c4d4ff8e5e041b1b44fe75727be3b47
77 Ndd79e6b0b77443d89e172253cd528b41
78 Ndfc095ab1f3d4f9a98ec016e6ba1d080
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034878037
80 https://doi.org/10.1007/s10620-008-0500-y
81 schema:sdDatePublished 2019-04-15T09:11
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher N65fb242d4f8342caa256b07b3136bba7
84 schema:url http://link.springer.com/10.1007/s10620-008-0500-y
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N015bd253429746d2b897bfe709de94ef rdf:first sg:person.0777635301.24
89 rdf:rest Nabf524f6215a499fa2624bc8e0db304b
90 N027a420383724cb889670558630790fe schema:name doi
91 schema:value 10.1007/s10620-008-0500-y
92 rdf:type schema:PropertyValue
93 N031886476ec24e51b53c2ff920d894dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Recombinant Proteins
95 rdf:type schema:DefinedTerm
96 N054ac629523040e6a9b6b5a7c35a893c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Polyethylene Glycols
98 rdf:type schema:DefinedTerm
99 N069fd002207544ce94d2a74aaeec1b8b rdf:first sg:person.012355406644.67
100 rdf:rest N3a0ab766ecca46e7821bd1ec391ac7eb
101 N166002015b024816b527cc2390193ec0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Antiviral Agents
103 rdf:type schema:DefinedTerm
104 N29efbd8dd903499f8b318a76b51da94b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Male
106 rdf:type schema:DefinedTerm
107 N2e6bf644ecb8483a995dad8d2099af6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Aging
109 rdf:type schema:DefinedTerm
110 N2fd9e447bff04d05be521592e45b4e5f schema:volumeNumber 54
111 rdf:type schema:PublicationVolume
112 N36326a3346f84692984f14252e99fc28 rdf:first sg:person.0760512552.26
113 rdf:rest Nafd5ee54856f40c995ffc78cb014e0e8
114 N3a0ab766ecca46e7821bd1ec391ac7eb rdf:first sg:person.016377110462.07
115 rdf:rest Nee3bd2f843cb4c2db1cf30d5b5df92db
116 N480cf8a43fee451696b7cbd54c1a1c72 schema:issueNumber 6
117 rdf:type schema:PublicationIssue
118 N48ccd559c7a34873aa226e9425c014f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Humans
120 rdf:type schema:DefinedTerm
121 N4b8f9b24e5c0481fb6789be152d47545 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Retrospective Studies
123 rdf:type schema:DefinedTerm
124 N4c32d32e39f94f1a80fb88e62ea5fcc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Ribavirin
126 rdf:type schema:DefinedTerm
127 N50ec06bd1d3a4fc59eee55c8fe4282bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Sex Characteristics
129 rdf:type schema:DefinedTerm
130 N5309015417e744019366a5bde35395cf rdf:first sg:person.01052350244.74
131 rdf:rest N36326a3346f84692984f14252e99fc28
132 N5f14a668393b4bab8a00cd84ef569898 rdf:first sg:person.01111770263.06
133 rdf:rest Nc2644e9fa13047c6a8288022acc833de
134 N621916dea16049c0a2482e7e457c9ea9 rdf:first sg:person.0662772733.31
135 rdf:rest N5f14a668393b4bab8a00cd84ef569898
136 N65fb242d4f8342caa256b07b3136bba7 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 N6a4d9d7450b9413896d32652dd09a880 rdf:first sg:person.01277062110.88
139 rdf:rest N621916dea16049c0a2482e7e457c9ea9
140 N6a810c4398d1457591bda3b8e0290f45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Female
142 rdf:type schema:DefinedTerm
143 N6af532475d0a4fdcb70d248e1828a9e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Middle Aged
145 rdf:type schema:DefinedTerm
146 N752d5297968645a199caaae3f61d8324 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Genotype
148 rdf:type schema:DefinedTerm
149 N7610309939184ac3b56515dcba872659 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Interferon-alpha
151 rdf:type schema:DefinedTerm
152 N7fcf93bc2c0c41cfaad5083e16731994 schema:name pubmed_id
153 schema:value 18958621
154 rdf:type schema:PropertyValue
155 N8277b2da396a4c368d9930617b3a4fb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Hepacivirus
157 rdf:type schema:DefinedTerm
158 N83c798e741d647dd85a22ca94cf02735 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Adult
160 rdf:type schema:DefinedTerm
161 N8c4d4ff8e5e041b1b44fe75727be3b47 schema:name nlm_unique_id
162 schema:value 7902782
163 rdf:type schema:PropertyValue
164 N9a208ee072cd43faa7381eb506775d8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Interferon alpha-2
166 rdf:type schema:DefinedTerm
167 Na7bff134916d4faead38ad82be1878e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Aged
169 rdf:type schema:DefinedTerm
170 Nabf524f6215a499fa2624bc8e0db304b rdf:first sg:person.0762121603.55
171 rdf:rest Ne5ee0dd8a697407cb9c5f776637a5041
172 Nafd5ee54856f40c995ffc78cb014e0e8 rdf:first sg:person.01110222601.87
173 rdf:rest N6a4d9d7450b9413896d32652dd09a880
174 Nc2644e9fa13047c6a8288022acc833de rdf:first sg:person.01237074644.17
175 rdf:rest N069fd002207544ce94d2a74aaeec1b8b
176 Nda1fdc7b62a9494b8599f9d176bfea4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Viral Load
178 rdf:type schema:DefinedTerm
179 Ndd79e6b0b77443d89e172253cd528b41 schema:name readcube_id
180 schema:value a6254b900772490c5e4f4c5d4cd319088f756f9c28607d04fd03b6993567c6b7
181 rdf:type schema:PropertyValue
182 Ndfc095ab1f3d4f9a98ec016e6ba1d080 schema:name dimensions_id
183 schema:value pub.1034878037
184 rdf:type schema:PropertyValue
185 Ndff459916f2a41abac9892932412d892 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Hepatitis C
187 rdf:type schema:DefinedTerm
188 Ne5ee0dd8a697407cb9c5f776637a5041 rdf:first sg:person.0625534344.87
189 rdf:rest rdf:nil
190 Nee3bd2f843cb4c2db1cf30d5b5df92db rdf:first sg:person.01351140444.35
191 rdf:rest N015bd253429746d2b897bfe709de94ef
192 Nfb569f49c9d0488283afd36569958000 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Young Adult
194 rdf:type schema:DefinedTerm
195 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
196 schema:name Medical and Health Sciences
197 rdf:type schema:DefinedTerm
198 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
199 schema:name Clinical Sciences
200 rdf:type schema:DefinedTerm
201 sg:journal.1018525 schema:issn 0163-2116
202 1573-2568
203 schema:name Digestive Diseases and Sciences
204 rdf:type schema:Periodical
205 sg:person.01052350244.74 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
206 schema:familyName Sezaki
207 schema:givenName Hitomi
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052350244.74
209 rdf:type schema:Person
210 sg:person.01110222601.87 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
211 schema:familyName Kawamura
212 schema:givenName Yusuke
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110222601.87
214 rdf:type schema:Person
215 sg:person.01111770263.06 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
216 schema:familyName Akuta
217 schema:givenName Norio
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111770263.06
219 rdf:type schema:Person
220 sg:person.012355406644.67 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
221 schema:familyName Suzuki
222 schema:givenName Yoshiyuki
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012355406644.67
224 rdf:type schema:Person
225 sg:person.01237074644.17 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
226 schema:familyName Kobayashi
227 schema:givenName Masahiro
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237074644.17
229 rdf:type schema:Person
230 sg:person.01277062110.88 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
231 schema:familyName Yatsuji
232 schema:givenName Hiromi
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277062110.88
234 rdf:type schema:Person
235 sg:person.01351140444.35 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
236 schema:familyName Arase
237 schema:givenName Yasuji
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351140444.35
239 rdf:type schema:Person
240 sg:person.016377110462.07 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
241 schema:familyName Saitoh
242 schema:givenName Satoshi
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016377110462.07
244 rdf:type schema:Person
245 sg:person.0625534344.87 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
246 schema:familyName Kumada
247 schema:givenName Hiromitsu
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625534344.87
249 rdf:type schema:Person
250 sg:person.0662772733.31 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
251 schema:familyName Hosaka
252 schema:givenName Tetsuya
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662772733.31
254 rdf:type schema:Person
255 sg:person.0760512552.26 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
256 schema:familyName Suzuki
257 schema:givenName Fumitaka
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760512552.26
259 rdf:type schema:Person
260 sg:person.0762121603.55 schema:affiliation https://www.grid.ac/institutes/grid.480868.a
261 schema:familyName Miyakawa
262 schema:givenName Yuzo
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762121603.55
264 rdf:type schema:Person
265 sg:person.0777635301.24 schema:affiliation https://www.grid.ac/institutes/grid.410813.f
266 schema:familyName Ikeda
267 schema:givenName Kenji
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777635301.24
269 rdf:type schema:Person
270 sg:pub.10.1007/s00535-003-1363-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004562363
271 https://doi.org/10.1007/s00535-003-1363-9
272 rdf:type schema:CreativeWork
273 https://app.dimensions.ai/details/publication/pub.1083116052 schema:CreativeWork
274 https://doi.org/10.1001/archinte.158.2.177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018087658
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1002/hep.1840190505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034162200
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1002/hep.1840360706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023592415
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1002/hep.20463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004698190
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1002/hep.510290307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004646384
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1002/jmv.20414 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046753742
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1002/jmv.20979 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037907405
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1002/lt.500030504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007147531
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/0016-5085(89)91629-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052595023
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1016/0016-5085(95)90207-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051419815
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/j.cgh.2006.05.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015713031
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/s0140-6736(96)07642-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043216718
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/s0140-6736(98)07124-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046778281
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/s0168-8278(99)80369-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011214576
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1046/j.1365-2893.2000.00233.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013939427
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1046/j.1440-1746.2000.02060.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025869053
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1046/j.1440-1746.2000.02368.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024636825
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1053/j.gastro.2006.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006919368
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1053/jhep.2000.8169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015241367
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1053/jlts.2003.50242 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037929478
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1055/s-2000-9505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057405288
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1056/nejm199302183280708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039848312
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1056/nejm199811193392101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004715205
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1056/nejm199904223401602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049024120
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1056/nejm199909163411202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048178958
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1056/nejmoa020047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013273688
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1086/368217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022668082
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1111/j.1478-3231.2006.01354.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043464355
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1111/j.1600-0676.1998.tb00150.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053504989
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1111/j.1872-034x.2007.00132.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041980279
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1126/science.285.5424.26 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062565771
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1136/gut.51.2.248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015401650
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1159/000087270 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045924056
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1159/000087273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010517484
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1210/jc.83.7.2266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064300282
343 rdf:type schema:CreativeWork
344 https://doi.org/10.7326/0003-4819-132-4-200002150-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073703937
345 rdf:type schema:CreativeWork
346 https://doi.org/10.7326/0003-4819-140-5-200403020-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073707203
347 rdf:type schema:CreativeWork
348 https://www.grid.ac/institutes/grid.410813.f schema:alternateName Toranomon Hospital
349 schema:name Department of Hepatology, Toranomon Hospital, Minato-ku, 105-8470, Tokyo, Japan
350 rdf:type schema:Organization
351 https://www.grid.ac/institutes/grid.480868.a schema:alternateName Miyakawa Memorial Research Foundation
352 schema:name Miyakawa Memorial Research Foundation, Tokyo, Japan
353 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...