Inverse Dose Effect of Pretest Dietary Lactose Intake on Breath Hydrogen Results and Symptoms in Lactase Nonpersistent Subjects View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-11

AUTHORS

Andrew Szilagyi, Paula Malolepszy, Samara Yesovitch, Usha Nathwani, Christina Vinokuroff, Albert Cohen, Xiaoqing Xue

ABSTRACT

The aim of this study was to determine a relationship between pretest intake of lactose and outcome of lactose breath hydrogen test. Patients presented at a testing laboratory participated in the study. A 3-hour breath hydrogen, 50-g lactose challenge was carried out. Results were tabulated and patients completed a 3-day recall diet questionnaire. Daily lactose intake was independently calculated and was associated with breath hydrogen and total symptom score. Statistical analysis used Spearman's correlation, Mann-Whitney U-test and chi2 or Fisher exact test. Of 118 patients, 50% were lactose maldigesters. In these patients, measured breath hydrogen and symptom scores were significantly higher in the lowest intake group (< 5 g/d) than in the highest intake group (> 20 g/d) (P < .05). In the presumed lactose digesters, 59% experienced some symptoms during testing for unclear reasons. Pretest dietary intake of lactose inversely affects results of breath hydrogen. More... »

PAGES

2178-2182

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10620-005-3028-4

DOI

http://dx.doi.org/10.1007/s10620-005-3028-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002054575

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16240236


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