Lipids from the Aerial Part of Scutellaria ramosissima View Full Text


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Article Info

DATE

2014-03

AUTHORS

N. K. Yuldasheva, N. T. Ul’chenko, N. Mamadalieva, A. I. Glushenkova, E. Ovidi, D. Triggiani, A. Tiezzi

ABSTRACT

Total lipids (TL) (2.1%), more than half of which were glycolipids (GL) (1.3%), and neutral lipids (NL) (0.54%) and phospholipids (PL) (0.26%) were isolated from the air-dried aerial part of Scutellaria ramosissima. The principal acids of the NL were 16:0, 18:2, and 18:3. Acid 16:0 (up to 40 mass% of the acids) dominated the glycolipids. Palmitic and linoleic acids dominated the PL with 18:1 in combination with 18:3 comprising slightly greater than 31%, like linoleic acid. The chlorophyll content was 197.3 mg% in the total lipids; carotinoids, 157.1 mg%; tocopherols, 357.0 mg% in unsaponified substances (US). The cytotoxic activity of the S. ramosissima lipid fractions was tested on HL-60 and HeLa cancer cell lines using the MTT test. PL, NL, and US showed cytotoxicity for HL-60 cells with IC50 values of 8.3, 22.0, and 24.3 μg/mL, respectively, and were inactive for HeLa cells. The GL and TL turned out to be slightly active. More... »

PAGES

68-71

References to SciGraph publications

  • 1992-03. Flavonoids of the epigeal part of Scutellaria ramosissima in CHEMISTRY OF NATURAL COMPOUNDS
  • 1994-05-01. Structures of two new flavonoids fromScutellaria ramosissima in CHEMISTRY OF NATURAL COMPOUNDS
  • 1970-09. Lipids of maturing grain of corn (Zea mays L.): in JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY
  • 2000-11. Lipids and Lipophilic Components of the Aerial Part of Daucus sativus in CHEMISTRY OF NATURAL COMPOUNDS
  • 1995-03. New flavone glycoside fromScutellaria ramosissima in CHEMISTRY OF NATURAL COMPOUNDS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10600-014-0868-1

    DOI

    http://dx.doi.org/10.1007/s10600-014-0868-1

    DIMENSIONS

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