Appropriate Operation for Elderly Colorectal Cancer Patients Based upon an Assessment of Preoperative Risk Factors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-07

AUTHORS

Yasuyuki Miyakura, Kazutomo Togashi, Fumio Konishi, Hisanaga Horie, Kazuhisa Shitoh, Masayuki Kojima, Masaya Ono, Masaki Okada, Hideo Nagai

ABSTRACT

Purpose. The correlation between age and the outcome following an operation for colorectal cancer (CRC) has not yet been determined. We studied the appropriate operation for elderly CRC patients based upon the assessment of preoperative risk factors. Methods. Seventy patients with Dukes' stages B or C CRC (more than 80 years old: aged group) and 66 stage-matched patients (50–69 years old: control group) were studied. The preoperative condition, the grade of surgical intervention, the perioperative activities of daily life (ADL), and the survival rate were compared between the two groups. Results. The preoperative conditions were significantly worse and the frequencies of patients with a deterioration in ADL during the perioperative period were significantly higher in the aged group. In the aged group, the peripheral lymphocyte count was significantly lower in patients with major postoperative complications, and the 1.0% forced expiratory volume (FEV1.0%) was significantly lower in patients with a deterioration in ADL. The low grade of surgical intervention tended to be related to a poor prognosis in rectal cancer of the aged group. Conclusion. The indications for operation in elderly CRC patients should be determined based upon an appropriate assessment of preoperative conditions, such as the lymphocyte count and FEV1.0%. More... »

PAGES

498-503

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10595-002-2532-x

DOI

http://dx.doi.org/10.1007/s10595-002-2532-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018189092

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/14506993


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