Synthesis of Monosubstituted Trifluoromethylated Derivatives of 2H-thiete, Dihydrothiophenes, and 2H-thiopyrans View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2022-02

AUTHORS

Serhii A. Siryi, Vadim М. Тimoshenko, Tymofii V. Rudenko, Yuriy M. Markitanov, Eduard B. Rusanov, Yuriy G. Shermolovich

ABSTRACT

Cyclic keto sulfides (thietan-3-one, tetrahydrothiophen-3-one, γ-thiobutyrolactone, δ-thiovalerolactone, thiopyran-3-one, and thiopyran-4-one) react with trifluoromethyltrimethylsilane (Ruppert–Prakash reagent) to afford trifluoromethyl-substituted hydroxysulfides which form monotrifluoromethyl-substituted cyclic unsaturated sulfones via successive oxidation and dehydration reactions. It was shown that the double bond in the obtained compounds is active toward nucleophilic reagents such as amino compounds and 1,3-dipoles. More... »

PAGES

106-115

References to SciGraph publications

  • 2011-09-23. Synthesis of Halogenated 5- and 6-Membered Sulfur- and Sulfur, Nitrogen-Containing Heterocycles in HALOGENATED HETEROCYCLES
  • 1981-04. Properties of molten alkali metal trifluoracetates in JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
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    http://scigraph.springernature.com/pub.10.1007/s10593-022-03063-0

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    http://dx.doi.org/10.1007/s10593-022-03063-0

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