Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-03

AUTHORS

Sergey P. Ivonin, Eduard B. Rusanov, Dmitriy M. Volochnyuk

ABSTRACT

An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl)ethanols based on recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is described. Oxidation by KMnO4 led to 2-(pyrazol-4-yl)-2-oxoacetic acids. In contrast, 2-(pyrazol-5-yl)ethanol under similar conditions gave only pyrazole-5-carboxylic acid, which formed as a result of oxidation followed by decarbonylation. 2-(Pyrazol-3-yl)ethanol in this oxidation reaction gave a mixture of 2-oxo-2-(pyrazol-3-yl)acetic acid and pyrazole-3-carboxylic acid. More... »

PAGES

320-325

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-020-02662-z

DOI

http://dx.doi.org/10.1007/s10593-020-02662-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1126748625


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0305", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Organic Chemistry", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.464621.3", 
          "name": [
            "Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ivonin", 
        "givenName": "Sergey P.", 
        "id": "sg:person.016634312021.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016634312021.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.464621.3", 
          "name": [
            "Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rusanov", 
        "givenName": "Eduard B.", 
        "id": "sg:person.01247600537.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247600537.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Taras Shevchenko National University of Kyiv, 60 Volodymyrska St, 01601, Kyiv, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.34555.32", 
          "name": [
            "Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine", 
            "Enamine Ltd, 78 Chervonotkatska St, 02094, Kyiv, Ukraine", 
            "Taras Shevchenko National University of Kyiv, 60 Volodymyrska St, 01601, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Volochnyuk", 
        "givenName": "Dmitriy M.", 
        "id": "sg:person.016137726667.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016137726667.84"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00426829", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052478051", 
          "https://doi.org/10.1007/bf00426829"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-03", 
    "datePublishedReg": "2020-03-01", 
    "description": "An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl)ethanols based on recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is described. Oxidation by KMnO4 led to 2-(pyrazol-4-yl)-2-oxoacetic acids. In contrast, 2-(pyrazol-5-yl)ethanol under similar conditions gave only pyrazole-5-carboxylic acid, which formed as a result of oxidation followed by decarbonylation. 2-(Pyrazol-3-yl)ethanol in this oxidation reaction gave a mixture of 2-oxo-2-(pyrazol-3-yl)acetic acid and pyrazole-3-carboxylic acid.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s10593-020-02662-z", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1429545", 
        "issn": [
          "0132-6244", 
          "1573-8353"
        ], 
        "name": "Chemistry of Heterocyclic Compounds", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "56"
      }
    ], 
    "keywords": [
      "pyrazole-5-carboxylic acid", 
      "pyrazole-3-carboxylic acid", 
      "result of oxidation", 
      "oxidation reaction", 
      "oxoacetic acid", 
      "recyclization reactions", 
      "oxidation", 
      "reaction", 
      "acid", 
      "similar conditions", 
      "decarbonylation", 
      "hydrazine", 
      "efficient approach", 
      "KMnO4", 
      "synthesis", 
      "preparation", 
      "mixture", 
      "conditions", 
      "contrast", 
      "results", 
      "approach"
    ], 
    "name": "Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols", 
    "pagination": "320-325", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1126748625"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10593-020-02662-z"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10593-020-02662-z", 
      "https://app.dimensions.ai/details/publication/pub.1126748625"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_835.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s10593-020-02662-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10593-020-02662-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10593-020-02662-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10593-020-02662-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10593-020-02662-z'


 

This table displays all metadata directly associated to this object as RDF triples.

101 TRIPLES      21 PREDICATES      47 URIs      38 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10593-020-02662-z schema:about anzsrc-for:03
2 anzsrc-for:0305
3 schema:author N0d5331734321468684566d67b5e9328c
4 schema:citation sg:pub.10.1007/bf00426829
5 schema:datePublished 2020-03
6 schema:datePublishedReg 2020-03-01
7 schema:description An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl)ethanols based on recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is described. Oxidation by KMnO4 led to 2-(pyrazol-4-yl)-2-oxoacetic acids. In contrast, 2-(pyrazol-5-yl)ethanol under similar conditions gave only pyrazole-5-carboxylic acid, which formed as a result of oxidation followed by decarbonylation. 2-(Pyrazol-3-yl)ethanol in this oxidation reaction gave a mixture of 2-oxo-2-(pyrazol-3-yl)acetic acid and pyrazole-3-carboxylic acid.
8 schema:genre article
9 schema:isAccessibleForFree false
10 schema:isPartOf N7003bd0f2b94426abb617b72d7c9afb2
11 Ne2b2b831b6c549e4a9fb8c810758b9ed
12 sg:journal.1429545
13 schema:keywords KMnO4
14 acid
15 approach
16 conditions
17 contrast
18 decarbonylation
19 efficient approach
20 hydrazine
21 mixture
22 oxidation
23 oxidation reaction
24 oxoacetic acid
25 preparation
26 pyrazole-3-carboxylic acid
27 pyrazole-5-carboxylic acid
28 reaction
29 recyclization reactions
30 result of oxidation
31 results
32 similar conditions
33 synthesis
34 schema:name Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols
35 schema:pagination 320-325
36 schema:productId N96fc2fd856c845c4bce63efa912a243a
37 Na8562f7119ab43718dd771a30b270c40
38 schema:sameAs https://app.dimensions.ai/details/publication/pub.1126748625
39 https://doi.org/10.1007/s10593-020-02662-z
40 schema:sdDatePublished 2022-10-01T06:46
41 schema:sdLicense https://scigraph.springernature.com/explorer/license/
42 schema:sdPublisher N2b49266ec6324ee99459deff5abe5b24
43 schema:url https://doi.org/10.1007/s10593-020-02662-z
44 sgo:license sg:explorer/license/
45 sgo:sdDataset articles
46 rdf:type schema:ScholarlyArticle
47 N0d5331734321468684566d67b5e9328c rdf:first sg:person.016634312021.16
48 rdf:rest N9f200c4e9cf94939a30f6e33fa0e7695
49 N2b49266ec6324ee99459deff5abe5b24 schema:name Springer Nature - SN SciGraph project
50 rdf:type schema:Organization
51 N7003bd0f2b94426abb617b72d7c9afb2 schema:volumeNumber 56
52 rdf:type schema:PublicationVolume
53 N96fc2fd856c845c4bce63efa912a243a schema:name doi
54 schema:value 10.1007/s10593-020-02662-z
55 rdf:type schema:PropertyValue
56 N9f200c4e9cf94939a30f6e33fa0e7695 rdf:first sg:person.01247600537.28
57 rdf:rest Nf6e0b771598e4b4fb509da747d9348c9
58 Na8562f7119ab43718dd771a30b270c40 schema:name dimensions_id
59 schema:value pub.1126748625
60 rdf:type schema:PropertyValue
61 Ne2b2b831b6c549e4a9fb8c810758b9ed schema:issueNumber 3
62 rdf:type schema:PublicationIssue
63 Nf6e0b771598e4b4fb509da747d9348c9 rdf:first sg:person.016137726667.84
64 rdf:rest rdf:nil
65 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
66 schema:name Chemical Sciences
67 rdf:type schema:DefinedTerm
68 anzsrc-for:0305 schema:inDefinedTermSet anzsrc-for:
69 schema:name Organic Chemistry
70 rdf:type schema:DefinedTerm
71 sg:journal.1429545 schema:issn 0132-6244
72 1573-8353
73 schema:name Chemistry of Heterocyclic Compounds
74 schema:publisher Springer Nature
75 rdf:type schema:Periodical
76 sg:person.01247600537.28 schema:affiliation grid-institutes:grid.464621.3
77 schema:familyName Rusanov
78 schema:givenName Eduard B.
79 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247600537.28
80 rdf:type schema:Person
81 sg:person.016137726667.84 schema:affiliation grid-institutes:grid.34555.32
82 schema:familyName Volochnyuk
83 schema:givenName Dmitriy M.
84 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016137726667.84
85 rdf:type schema:Person
86 sg:person.016634312021.16 schema:affiliation grid-institutes:grid.464621.3
87 schema:familyName Ivonin
88 schema:givenName Sergey P.
89 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016634312021.16
90 rdf:type schema:Person
91 sg:pub.10.1007/bf00426829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052478051
92 https://doi.org/10.1007/bf00426829
93 rdf:type schema:CreativeWork
94 grid-institutes:grid.34555.32 schema:alternateName Taras Shevchenko National University of Kyiv, 60 Volodymyrska St, 01601, Kyiv, Ukraine
95 schema:name Enamine Ltd, 78 Chervonotkatska St, 02094, Kyiv, Ukraine
96 Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine
97 Taras Shevchenko National University of Kyiv, 60 Volodymyrska St, 01601, Kyiv, Ukraine
98 rdf:type schema:Organization
99 grid-institutes:grid.464621.3 schema:alternateName Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine
100 schema:name Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, 02660, Kyiv, Ukraine
101 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...