Study of regioselectivity in cyanomethylation of 4-(trifluoromethyl)pyrimidin-2(1Н)-ones View Full Text


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Article Info

DATE

2019-02-20

AUTHORS

Viktor M. Tkachuk, Serhii V. Melnykov, Anastasiia V. Vorobei, Volodymyr A. Sukach, Mykhailo V. Vovk

ABSTRACT

Cyanoacetic acid reacted selectively with 4-(trifluoromethyl)pyrimidin-2(1Н)-ones with the formation of Michael addition–decarboxylation products in DMSO solution at 85°С and Mannich reaction products when the reagents were fused together under solventfree conditions.

PAGES

1-6

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-019-02420-w

DOI

http://dx.doi.org/10.1007/s10593-019-02420-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112261939


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