Synthesis, annulation, and heterofunctionalization of 4-hydrazinylpyrazolo[1,5-а]pyrazines View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07

AUTHORS

Nazar M. Tsizorik, Yevhenii V. Hrynyshyn, Anna R. Musiychuk, Andriy V. Bol’but, Nadezhda V. Panasenko, Mikhailo V. Vovk

ABSTRACT

4-Hydrazinylpyrazolo[1,5-а]pyrazines were obtained by reactions of 4-chloropyrazolo[1,5-а]pyrazines with hydrazine hydrate and further combined with compounds having one reactive site (triethyl orthoformate, acetic anhydride, ethyl chloroformate, phenyl isothiocyanate, hydrazoic acid) or two reactive sites (diethyl oxalate), forming the respective derivatives containing fused 1,2,4-triazole, tetrazole, or 1,2,4-triazine rings. The reactions with acetylacetone and ethoxymethylene derivatives of malononitrile or ethyl cyanoacetate were used to synthesize 4-(1-pyrazolyl)-substituted pyrazolo[1,5-а]pyrazines. More... »

PAGES

710-716

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-018-2337-4

DOI

http://dx.doi.org/10.1007/s10593-018-2337-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106388485


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